期刊
GLYCOCONJUGATE JOURNAL
卷 33, 期 6, 页码 841-851出版社
SPRINGER
DOI: 10.1007/s10719-016-9720-0
关键词
Glycosaminoglycan; Chondroitin sulfate; Dermatan sulfate; Sulfatase
资金
- National Natural Science Foundation of China [31570071]
- Major State Basic Research Development Program of China [2012CB822102]
- Shenzhen strategic emerging industry development special funds [JCYJ20140418115815063]
Sulfatases that specifically catalyze the hydrolysis of the sulfate groups on chondroitin sulfate (CS)/dermatan sulfate (DS) poly- and oligosaccharides belong to the formylglycine-dependent family of sulfatases and have been widely found in various mammalian and bacterial organisms. However, only a few types of CS/DS sulfatase have been identified so far. Recently, several novel CS/DS sulfatases have been cloned and characterized. Advanced studies have provided significant insight into the biological function and mechanism of action of CS/DS sulfatases. Moreover, further studies will provide powerful tools for structural and functional studies of CS/DS as well as related applications. This article reviews the recent progress in CS/DS sulfatase research and is expected to initiate further research in this field.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据