4.6 Article

Evaluation of the Clinical Use of Ceftriaxone among In-Patients in Selected Health Facilities in Uganda

期刊

ANTIBIOTICS-BASEL
卷 10, 期 7, 页码 -

出版社

MDPI
DOI: 10.3390/antibiotics10070779

关键词

antimicrobials; ceftriaxone; drug utilization review

资金

  1. National Drug Authority (NDA) Uganda [NDA/CONS/18-19/00011]

向作者/读者索取更多资源

The study assessed the clinical utilization of ceftriaxone in Uganda and found that there was a significant rate of inappropriate use, with some patients not completing their prescribed doses. Factors associated with appropriate ceftriaxone use included gender, pregnancy status, days of hospitalization, health facility level of care, health facility type, and type of prescriber.
Ceftriaxone has a high propensity for misuse because of its high rate of utilization. In this study, we aimed at assessing the appropriateness of the clinical utilization of ceftriaxone in nine health facilities in Uganda. Using the World Health Organization (WHO) Drug Use Evaluation indicators, we reviewed a systematic sample of 885 patients' treatment records selected over a three (3)-month period. Our results showed that prescriptions were written mostly by medical officers at 53.3% (470/882). Ceftriaxone was prescribed mainly for surgical prophylaxis at 25.3% (154/609), respiratory tract infections at 17% (104/609), and sepsis at 11% (67/609), as well as for non-recommended indications such as malaria at 7% (43/609) and anemia at 8% (49/609). Ceftriaxone was mostly prescribed once daily (92.3%; 817/885), as a 2 g dose (50.1%; 443/885), and for 5 days (41%; 363/885). The average score of inappropriate use of ceftriaxone in the eight indicators was 32.1%. Only 58.3% (516/885) of the ceftriaxone doses prescribed were administered to completion. Complete blood count and culture and sensitivity testing rates were 38.8% (343/885) and 1.13% (10/885), respectively. Over 85.4% (756/885) of the patients improved and were discharged. Factors associated with appropriate ceftriaxone use were gender, pregnancy status, days of hospitalization, health facility level of care, health facility type, and type of prescriber.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据