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A Systematic Review on the Antimicrobial Properties of Mediterranean Wild Edible Plants: We Still Know Too Little about Them, but What We Do Know Makes Persistent Investigation Worthwhile

期刊

FOODS
卷 10, 期 9, 页码 -

出版社

MDPI
DOI: 10.3390/foods10092217

关键词

wild edible plants; antimicrobial effect; Mediterranean plant; Gram+ bacteria; Gram- bacteria; extraction protocols; bioactive compounds; essential oils

资金

  1. National Research Council

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Research on Mediterranean wild edible plants (MWEPs) with antimicrobial properties showed that the majority of species exhibited antimicrobial activities, but the studies remain heterogeneous and more investigation is needed.
(1) Introduction: Bacterial resistance to antibiotics is estimated to be the cause of a major number of deaths by 2050 if we do not find strategies to slow down the rise of drug resistance. Reviews on Mediterranean wild edible plants (MWEPs) with antimicrobial properties are scarce in the main databases (PubMed, Scopus, and WoS). Hence, we proceeded to conduct a new review of the studies on MWEPs. (2) Methods: We used 'wild edible plant' and 'antimicrobial' as keywords. Within this group, exclusion criteria were reviews, studies concerning non-Mediterranean plants or non-edible plants, studies on topics other than plants or containing no description of antimicrobial properties, or off-topic studies. (3) Results: Finally, out of the one hundred and ninety-two studies we had started with, we reviewed thirty-eight (19.8%) studies concerning the antimicrobial properties of seventy-four MWEPs species belonging to twenty-five Families. Fifty-seven (77%) species out of seventy-four proved to be antimicrobial, with a stringent threshold selection. (4) Conclusions: Studies are still very heterogeneous. We still know too little about MWEPs' properties; however, what we already know strongly recommends carrying on investigation.

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