期刊
CURRENT OPINION IN BEHAVIORAL SCIENCES
卷 40, 期 -, 页码 58-63出版社
ELSEVIER
DOI: 10.1016/j.cobeha.2021.01.004
关键词
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资金
- National Institute of Mental Health [MH094258]
- National Institutes of Health [NS103780]
- Kiwanis Neuroscience Research Foundation
Researchers argue that there is still valuable in single-case lesion-deficit research combined with fMRI methods, which provide unique opportunities to address challenging unanswered questions about brain-behavior relationships, as demonstrated by notable findings in recent years.
Although lesion-deficit case studies are foundational in cognitive neuroscience, published papers presenting single lesion cases are declining. In this review, we argue that there is a valuable place for single-case lesion-deficit research, especially when combined with functional neuroimaging methods, such as functional magnetic resonance imaging (fMRI). To support this, we present a summary of notable findings from single-case combined lesion-deficit and fMRI studies published in recent years (2017-2020). These studies show the unique value that this combined approach brings to the understanding of complex functions, brain-level connectivity, and plasticity and recovery. We encourage researchers to consider combining lesion-deficit and functional imaging methods in the analysis of single cases, as this approach affords unique opportunities to address challenging unanswered questions about brain-behavior relationships.
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