4.6 Review

A Minireview of the Promising Drugs and Vaccines in Pipeline for the Treatment of COVID-19 and Current Update on Clinical Trials

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Editorial Material Medicine, General & Internal

Sputnik V COVID-19 vaccine candidate appears safe and effective Comment

Ian Jones et al.

LANCET (2021)

Article Critical Care Medicine

Sarilumab in patients admitted to hospital with severe or critical COVID-19: a randomised, double-blind, placebo-controlled, phase 3 trial

Francois-Xavier Lescure et al.

Summary: This study aimed to evaluate the safety and efficacy of sarilumab in patients with severe or critical COVID-19, but found no significant efficacy in patients admitted to the hospital receiving supplemental oxygen. Future adequately powered trials of targeted immunomodulatory therapies with survival as a primary endpoint are suggested for patients with critical COVID-19.

LANCET RESPIRATORY MEDICINE (2021)

Editorial Material Immunology

Access to and equitable distribution of COVID-19 vaccine in low-income countries

Krishna Prasad Acharya et al.

NPJ VACCINES (2021)

Review Biochemistry & Molecular Biology

Perspectives on RNA Vaccine Candidates for COVID-19

Pobitra Borah et al.

Summary: With the outbreak of COVID-19, vaccination has become a public health care priority. RNA vaccines are considered the next generation vaccines with advantages such as less prone to host genome integration and anti-vector immunity. According to the World Health Organization, seven potential RNA-based COVID-19 vaccines are in different stages of clinical trials, with some already receiving emergency use authorization.

FRONTIERS IN MOLECULAR BIOSCIENCES (2021)

Review Biochemistry & Molecular Biology

Developmental Landscape of Potential Vaccine Candidates Based on Viral Vector for Prophylaxis of COVID-19

Rajashri Bezbaruah et al.

Summary: The development of COVID-19 vaccines is considered the most efficient strategy to contain the ongoing pandemic, and extensive global research and development work is underway. Various technology platforms are being evaluated, including virus-like particles, nucleic acids, proteins, and viral vectors.

FRONTIERS IN MOLECULAR BIOSCIENCES (2021)

Article Medicine, General & Internal

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

Chaolin Huang et al.

LANCET (2020)

Review Pharmacology & Pharmacy

Current pharmacological treatments for COVID-19: What's next?

Cristina Scavone et al.

BRITISH JOURNAL OF PHARMACOLOGY (2020)

Article Infectious Diseases

Cytokine storm and immunomodulatory therapy in COVID-19: Role of chloroquine and anti-IL-6 monoclonal antibodies

Ming Zhao

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2020)

Article Infectious Diseases

Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial

Philippe Gautret et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2020)

Article Virology

Tocilizumab treatment in COVID-19: A single center experience

Pan Luo et al.

JOURNAL OF MEDICAL VIROLOGY (2020)

Article Immunology

COVID-19 vaccines: breaking record times to first-in-human trials

Young Chan Kim et al.

NPJ VACCINES (2020)

Article Engineering, Multidisciplinary

Experimental Treatment with Favipiravir for COVID-19: An Open-Label Control Study

Qingxian Cai et al.

ENGINEERING (2020)

Article Medicine, General & Internal

A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19

B. Cao et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Multidisciplinary Sciences

COVID-19 infection: Origin, transmission, and characteristics of human coronaviruses

Muhammad Adnan Shereen et al.

JOURNAL OF ADVANCED RESEARCH (2020)

Review Pharmacology & Pharmacy

Chloroquine and hydroxychloroquine in the treatment of malaria and repurposing in treating COVID-19

Zi-Ning Lei et al.

PHARMACOLOGY & THERAPEUTICS (2020)

Review Infectious Diseases

A short review on antibody therapy for COVID-19

G. Venkat Kumar et al.

NEW MICROBES AND NEW INFECTIONS (2020)

Article Pharmacology & Pharmacy

Discovering drugs to treat coronavirus disease 2019 (COVID-19)

Liying Dong et al.

DRUG DISCOVERIES AND THERAPEUTICS (2020)

Review Pharmacology & Pharmacy

T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections

Yousuke Furuta et al.

ANTIVIRAL RESEARCH (2009)