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Article
Virology
Adrien Biguenet et al.
Summary: The respiratory viral loads of SARS-CoV-2 in infected patients decrease steadily during the acute phase of infection. While the viral loads are not strongly correlated with COVID-19 symptoms and outcome, determining the level of viral loads may help predict the onset of virus shedding in a specific patient. The role of SARS-CoV-2 viral loads as a biomarker of severity is limited.
JOURNAL OF MEDICAL VIROLOGY
(2021)
Article
Immunology
Maria Skaalum Petersen et al.
Summary: The study showed that over half of COVID-19 patients still had at least one symptom persisting after an average of 125 days post-symptom onset, with fatigue, loss of smell and taste, and arthralgias being the most prevalent persistent symptoms. At the last follow-up, 46.9% of patients were asymptomatic compared to only 4.4% during the acute phase. Continued monitoring for long COVID is necessary.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Infectious Diseases
Oscar Moreno-Perez et al.
Summary: This study found that Post-acute COVID-19 syndrome was detected in about half of COVID-19 survivors, with mostly mild symptoms. Radiological and spirometric changes were observed in less than 25% of patients, and no baseline clinical features behaved as independent predictors of Post-acute COVID-19 syndrome development.
JOURNAL OF INFECTION
(2021)
Article
Medicine, General & Internal
Chaolin Huang et al.
Summary: This study aimed to investigate the long-term health consequences of discharged COVID-19 patients and associated risk factors, particularly disease severity. Patients with more severe illness during hospitalization showed more severe impaired pulmonary diffusion capacities and abnormal chest imaging manifestations, highlighting the need for targeted interventions for long-term recovery.
Article
Immunology
Souheil Zayet et al.
Summary: This article describes cases of coronavirus recurrence in healthcare workers in France, emphasizing the potential risk of COVID-19 relapse.
MICROBES AND INFECTION
(2021)
Article
Immunology
Steffen Leth et al.
Summary: The study found that 96% of recovered patients from COVID-19 still reported one or more persistent symptoms at 12 weeks post-hospitalization, with fatigue, dyspnea, cough, chemosensory dysfunction, and headache being the main symptoms. This calls for larger descriptive studies and interdisciplinary research collaborations to further understand the wide range of persistent symptoms in COVID-19 patients.
OPEN FORUM INFECTIOUS DISEASES
(2021)
Article
Infectious Diseases
Bodunrin Osikomaiya et al.
Summary: The study found that over one-third of COVID-19 survivors experience persistent symptoms after discharge, with common symptoms being fatigue, headaches, and chest pain. The severity of symptomatic COVID-19 disease may predict the presence of these persistent symptoms.
BMC INFECTIOUS DISEASES
(2021)
Article
Infectious Diseases
Yolanda Meije et al.
Summary: This study aimed to describe the long-term outcomes of COVID-19 survivors who were followed up both at an outpatient facility and by telephone. It found that most patients still experienced symptoms, with those having lower Pao(2)/Fio(2) ratios during acute illness requiring special attention.
CLINICAL MICROBIOLOGY AND INFECTION
(2021)
Article
Critical Care Medicine
Miguel A. Martillo et al.
Summary: The study aimed to determine the characteristics of post-intensive care syndrome in cognitive, physical, and psychiatric domains in 2019 coronavirus disease ICU survivors. The results showed that 91% of ICU survivors met diagnostic criteria for post-intensive care syndrome, with impairments in the physical, psychiatric, and cognitive domains. These findings emphasize the importance of planning for appropriate post-ICU care for this high-risk population.
CRITICAL CARE MEDICINE
(2021)
Article
Otorhinolaryngology
Juan Riestra-Ayora et al.
Summary: In COVID-19 patients, olfactory and gustatory dysfunction showed high-resolution rates within the first two months after onset, but 11% did not fully recover and 30% partially recovered after 6 months. There was a high correlation between olfactory and gustatory dysfunction, while nasal obstruction and dyspnea were identified as risk factors for symptom persistence.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2021)
Article
Infectious Diseases
Lucas Armange et al.
Summary: The study showed that 53.7% of outpatients with non-severe COVID-19 had recovered after 6 weeks, but many still experienced persistent symptoms such as dyspnea, weight loss, sleep disorders, and anxiety. Some patients also continued to have ageusia and anosmia at week 6.
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
(2021)
Letter
Medicine, General & Internal
Sebastian Havervall et al.
Summary: This study found that COVID-19-related symptoms can persist for 8 months among Swedish health care workers, and these symptoms have effects on their home, work, and social functions.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2021)
Editorial Material
Clinical Neurology
[Anonymous]
Review
Biochemistry & Molecular Biology
Ani Nalbandian et al.
Summary: SARS-CoV-2 is responsible for the COVID-19 pandemic, causing global healthcare crises. Recovery from COVID-19 may lead to persistent symptoms and long-term complications, prompting the need for multidisciplinary care and follow-up for survivors.
Article
Respiratory System
Claire F. McGroder et al.
Summary: Patients who underwent mechanical ventilation for severe COVID-19 are more likely to develop fibrotic-like radiographic abnormalities after hospitalisation. The severity of initial illness, duration of mechanical ventilation, lactate dehydrogenase on admission, and leucocyte telomere length are independent risk factors for these abnormalities, which are correlated with lung function, cough, and frailty measures, but not with dyspnoea.
Article
Infectious Diseases
Kanika Sehgal et al.
Summary: The study found that coinfection of COVID-19 and CDI is not uncommon, and the clinical characteristics, treatment, and outcomes of these patients need to be further understood. Further investigations are necessary to explore the relationship between these two infections and to guide future clinical practices effectively.
INFECTION AND DRUG RESISTANCE
(2021)
Article
Psychology, Multidisciplinary
Jessica Ranieri et al.
Summary: This study aimed to analyze the risk of posttraumatic stress disorder among nurses in the Italian COVID-19 outbreak, finding a relationship between anxiety, personality traits, and post-traumatic stress. Emotional distress was found to persist over time, with long-term personality traits serving as a mediator in facing subjective stress.
FRONTIERS IN PSYCHOLOGY
(2021)
Review
Infectious Diseases
Sonia Poenaru et al.
Summary: COVID-19 can lead to a prolonged convalescence with chronic symptoms resembling those of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), although more research is needed to confirm any link between the two conditions.
THERAPEUTIC ADVANCES IN INFECTIOUS DISEASE
(2021)
Review
Infectious Diseases
Tawee Chotpitayasunondh et al.
Summary: The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, has had a major impact on healthcare and social systems worldwide. There is a need to manage both COVID-19 and influenza concurrently, ensuring effective surveillance and diagnostic capabilities to monitor respiratory viruses, and advocating for judicious use of vaccines and antivirals. The increased use of emerging technologies, such as telemedicine and contact tracing, alongside existing pharmaceutical strategies, will provide a holistic approach to global public health measures in dealing with the combined threat of influenza and COVID-19.
INFLUENZA AND OTHER RESPIRATORY VIRUSES
(2021)
Article
Medicine, General & Internal
Andrea Dennis et al.
Summary: A study conducted in two UK community centers found that 70% of individuals with persistent symptoms following recovery from SARS-CoV-2 infection had impairment in one or more organs 4 months after initial COVID-19 symptoms. Common symptoms included fatigue, muscle aches, breathlessness, and headaches.
Article
Otorhinolaryngology
Jerome R. Lechien et al.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2020)
Article
Infectious Diseases
T. Klopfenstein et al.
MEDECINE ET MALADIES INFECTIEUSES
(2020)
Article
Emergency Medicine
Yu Fang et al.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2020)
Editorial Material
Medicine, General & Internal
Trisha Greenhalgh et al.
BMJ-BRITISH MEDICAL JOURNAL
(2020)
Editorial Material
Critical Care Medicine
Mansoor N. Bangash et al.
LANCET RESPIRATORY MEDICINE
(2020)
Letter
Infectious Diseases
Alice Norton et al.
LANCET INFECTIOUS DISEASES
(2020)