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JOURNAL OF CELL SCIENCE (2010)
Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney
Shinji Kume et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
SRT1720 Induces Mitochondrial Biogenesis and Rescues Mitochondrial Function after Oxidant Injury in Renal Proximal Tubule Cells
Jason A. Funk et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
Matthew D. Hirschey et al.
NATURE (2010)
The suffocating kidney: tubulointerstitial hypoxia in end-stage renal disease
Imari Mimura et al.
NATURE REVIEWS NEPHROLOGY (2010)
Protein deacetylation by SIRT1: An emerging key post-translational modification in metabolic regulation
Jiujiu Yu et al.
PHARMACOLOGICAL RESEARCH (2010)
Extending Healthy Life Span-From Yeast to Humans
Luigi Fontana et al.
SCIENCE (2010)
Nicotinamide phosphoribosyltransferase imparts human endothelial cells with extended replicative lifespan and enhanced angiogenic capacity in a high glucose environment
Nica M. Borradaile et al.
AGING CELL (2009)
How mitochondria produce reactive oxygen species
Michael P. Murphy
BIOCHEMICAL JOURNAL (2009)
SIRT5 Deacetylates Carbamoyl Phosphate Synthetase 1 and Regulates the Urea Cycle
Takashi Nakagawa et al.
CELL (2009)
Abnormal Angiogenesis in Diabetic Nephropathy
Takahiko Nakagawa et al.
DIABETES (2009)
Effects of Resveratrol on H2O2-Induced Apoptosis and Expression of SIRTs in H9c2 Cells
Wei Yu et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2009)
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
Carles Canto et al.
NATURE (2009)
The Pathogenic Role of Notch Activation in Podocytes
Thiruvur Niranjan et al.
NEPHRON EXPERIMENTAL NEPHROLOGY (2009)
BRAIN INFLAMMATION AND ADULT NEUROGENESIS: THE DUAL ROLE OF MICROGLIA
C. T. Ekdahl et al.
NEUROSCIENCE (2009)
Redox control of renal function and hypertension
Ravi Nistala et al.
ANTIOXIDANTS & REDOX SIGNALING (2008)
Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice
Olesya Vakhrusheva et al.
CIRCULATION RESEARCH (2008)
FoxO transcription factors in the maintenance of cellular homeostasis during aging
Dervis A. M. Salih et al.
CURRENT OPINION IN CELL BIOLOGY (2008)
Oxidative stress as a major culprit in kidney disease in diabetes
Josephine M. Forbes et al.
DIABETES (2008)
Production, detection, and adaptive responses to free radicals in exercise
Sean Sachdev et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging
Richard I. Morimoto
GENES & DEVELOPMENT (2008)
SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1 - Possible role in AMP-activated protein kinase activation
Fan Lan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Substrates and regulation mechanisms for the human mitochondrial Sirtuins Sirt3 and Sirt5
Christine Schlicker et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition
Debra F. Higgins et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Manganese superoxide dismutase protects mouse cortical neurons from chronic intermittent hypoxia-mediated oxidative damage
Xiaoyang Shan et al.
NEUROBIOLOGY OF DISEASE (2007)
Sirt1 modulates premature senescence-like phenotype in human endothelial cells
Hidetaka Ota et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2007)
Biochemistry of oxidative stress
B. Halliwell
BIOCHEMICAL SOCIETY TRANSACTIONS (2007)
SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase
Ilwola Mattagajasingh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation
Enxuan Jing et al.
CELL METABOLISM (2007)
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1α
Zachary Gerhart-Hines et al.
EMBO JOURNAL (2007)
Intermittent fasting prevents the progression of type I diabetic nephropathy in rats and changes the expression of Sir2 and p53
Kulbhushan Tikoo et al.
FEBS LETTERS (2007)
Oxyl radicals, redox-sensitive signalling cascades and antioxidants
Marcelo Genestra
CELLULAR SIGNALLING (2007)
Modular activation of nuclear factor-κB transcriptional programs in human diabetic nephropathy
Holger Schmid et al.
DIABETES (2006)
Oxidative stress is progressively enhanced with advancing stages of CKD
Evangelia Dounousi et al.
AMERICAN JOURNAL OF KIDNEY DISEASES (2006)
OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion
Christian Frezza et al.
CELL (2006)
Diabetes promotes cardiac stem cell aging and heart failure, which are prevented by deletion of the p66shc gene
Marcello Rota et al.
CIRCULATION RESEARCH (2006)
Smad3 is key to TGF-β-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis
AB Roberts et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2006)
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
R Mostoslavsky et al.
CELL (2006)
Chronic hypoxia and tubulointerstitial injury: A final common pathway to end-stage renal failure
Masaomi Nangaku
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)
The antioxidant function of the p53 tumor suppressor
AA Sablina et al.
NATURE MEDICINE (2005)
Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
E Michishita et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
JT Rodgers et al.
NATURE (2005)
A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages
D Bellizzi et al.
GENOMICS (2005)
p53-induced up-regulation of MnSOD and GPx but not catalase increases oxidative stress and apoptosis
SP Hussain et al.
CANCER RESEARCH (2004)
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
A Brunet et al.
SCIENCE (2004)
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate for proteasomal degradation of Nrf2
A Kobayashi et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
HY Cohen et al.
SCIENCE (2004)
Angiogenesis induced by photodynamic therapy in normal rat brain
F Jiang et al.
PHOTOCHEMISTRY AND PHOTOBIOLOGY (2004)
The chemistry of nitrosative stress induced by nitric oxide and reactive nitrogen oxide species. Putting perspective on stressful biological situations
LA Ridnour et al.
BIOLOGICAL CHEMISTRY (2004)
Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly
G Rose et al.
EXPERIMENTAL GERONTOLOGY (2003)
Biological chemistry of reactive oxygen and nitrogen and radiation-induced signal transduction mechanisms
RB Mikkelsen et al.
ONCOGENE (2003)
Redox signaling in vascular angiogenesis
N Maulik et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration
SJ Lin et al.
NATURE (2002)
Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway
S Nemoto et al.
SCIENCE (2002)
hSIR2SIRT1 functions as an NAD-dependent p53 deacetylase
H Vaziri et al.
CELL (2001)
Mitochondrial dysfunction in cardiac disease: Ischemia-reperfusion, aging, and heart failure
EJ Lesnefsky et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2001)
Hypochlorous acid produced by the myeloperoxidase system of human phagocytes induces covalent cross-links between DNA and protein
PA Kulcharyk et al.
BIOCHEMISTRY (2001)
Antioxidants in health and disease
IS Young et al.
JOURNAL OF CLINICAL PATHOLOGY (2001)
Mitochondrial genetics and disease
EA Schon
TRENDS IN BIOCHEMICAL SCIENCES (2000)
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
S Imai et al.
NATURE (2000)
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