期刊
ANTIOXIDANTS
卷 10, 期 7, 页码 -出版社
MDPI
DOI: 10.3390/antiox10071034
关键词
carotenoids; coenzyme Q10; lipid nanoparticles; solid lipid nanoparticles; nanostructured lipid carriers; topical administration
资金
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [2019/16169-0]
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq) [305250/2019-1]
- Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior-Brasil (CAPES) [001]
- Foundation for Science and Technology (FCT, Portugal) [UIDB/04567/2020, UIDP/04567/2020]
This review discusses the encapsulation of carotenoids and coenzyme Q10 in lipid nanoparticles to enhance their bioavailability and skin absorption, as well as highlighting their cytotoxic and photoprotective effects on the skin.
Carotenoids and coenzyme Q10 are naturally occurring antioxidant compounds that are also found in human skin. These bioactive compounds have been the focus of considerable research due to their antioxidant, anti-inflammatory, and photoprotective properties. In this review, the current state of the art in the encapsulation of carotenoids and coenzyme Q10 in lipid nanoparticles to improve their bioavailability, chemical stability, and skin absorption is discussed. Additionally, the main findings are highlighted on the cytotoxic and photoprotective effects of these systems in the skin.
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