4.7 Review

Nanoparticle-Based Therapies for Turning Cold Tumors Hot: How to Treat an Immunosuppressive Tumor Microenvironment

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Materials Science, Multidisciplinary

Use of macrophage as a Trojan horse for cancer nanotheranostics

Yu Qi et al.

Summary: Nano-based cancer theranostics face challenges in achieving expected efficacy due to low nanoparticle accumulation in tumors. Cell-aided strategies, particularly involving macrophages, show promise in improving the therapeutic efficacy of nanomedicines. Further research is needed to understand the interactions between macrophages, nanomedicines, and tumor cells for enhancing anti-cancer immunity in the tumor microenvironment.

MATERIALS & DESIGN (2021)

Article Materials Science, Multidisciplinary

Gene silencing-mediated immune checkpoint blockade for tumor therapy boosted by dendrimer-entrapped gold nanoparticles

Xue Xue et al.

Summary: The study developed a functional nanoplatform based on G5 PAMAM dendrimer-entrapped gold nanoparticles for delivering siPD-L1 to achieve PD-L1 gene silencing-mediated tumor immunotherapy. The functional Au DENPs successfully delivered siPD-L1 to cancer cells, efficiently knocking down PD-L1 protein expression and enhancing the efficacy of ICB-based immunotherapy.

SCIENCE CHINA-MATERIALS (2021)

Article Engineering, Biomedical

Prolonged activation of innate immune pathways by a polyvalent STING agonist

Suxin Li et al.

Summary: A novel polyvalent STING agonist extends the activation of innate-immunity pathways through the formation of STING condensates and leads to synergistic therapeutic outcomes in vivo when combined with the STING ligand cGAMP.

NATURE BIOMEDICAL ENGINEERING (2021)

Review Engineering, Biomedical

Peptide functionalized liposomes for receptor targeted cancer therapy

Matthew R. Aronson et al.

Summary: Loading chemotherapy drugs into liposomes can reduce toxicity in patients, but passive targeting issues remain. Modifying liposome surfaces allows for tumor targeting and controlled drug delivery. Peptides can be used as ligands for tumor cell localization.

APL BIOENGINEERING (2021)

Article Medicine, Research & Experimental

Collagenase IV and clusterin-modified polycaprolactone-polyethylene glycol nanoparticles for penetrating dense tumor tissues

Hao-Yan Huang et al.

Summary: The novel ColIV and CLU-modified PCL-PEG nanoparticles demonstrated excellent antitumor effects, as well as outstanding performance in cellular uptake, ECM penetration, and antiphagocytosis both in vitro and in vivo.

THERANOSTICS (2021)

Article Multidisciplinary Sciences

Highly efficient and tumor-selective nanoparticles for dual-targeted immunogene therapy against cancer

Kuan-Wei Huang et al.

SCIENCE ADVANCES (2020)

Review Chemistry, Multidisciplinary

Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy

Jing Gao et al.

ACTA PHARMACOLOGICA SINICA (2020)

Editorial Material Biochemistry & Molecular Biology

cGAMP as an Adjuvant in Antiviral Vaccines and Cancer Immunotherapy

Christopher Ritchie et al.

BIOCHEMISTRY (2020)

Article Medicine, Research & Experimental

TLR7/8 Agonist-Loaded Nanoparticles Augment NK Cell-Mediated Antibody-Based Cancer Immunotherapy

Hyunjoon Kim et al.

MOLECULAR PHARMACEUTICS (2020)

Article Multidisciplinary Sciences

Cellular backpacks for macrophage immunotherapy

C. Wyatt Shields et al.

SCIENCE ADVANCES (2020)

Article Oncology

Potent STING activation stimulates immunogenic cell death to enhance antitumor immunity in neuroblastoma

Lihong Wang-Bishop et al.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020)

Review Pharmacology & Pharmacy

Small molecules targeting the innate immune cGAS-STING-TBK1 signaling pathway

Chunyong Ding et al.

ACTA PHARMACEUTICA SINICA B (2020)

Review Pharmacology & Pharmacy

Polymeric Nanocarriers of Drug Delivery Systems in Cancer Therapy

Natasa Avramovic et al.

PHARMACEUTICS (2020)

Article Multidisciplinary Sciences

Trispecific natural killer cell nanoengagers for targeted chemoimmunotherapy

Kin Man Au et al.

SCIENCE ADVANCES (2020)

Review Chemistry, Medicinal

Gold Nanoparticles: A New Golden Era in Oncology?

Clara Gerosa et al.

PHARMACEUTICALS (2020)

Article Biochemistry & Molecular Biology

Nanoparticles Presenting Potent TLR7/8 Agonists Enhance Anti-PD-L1 Immunotherapy in Cancer Treatment

Anton A. A. Smith et al.

BIOMACROMOLECULES (2020)

Review Biochemistry & Molecular Biology

Lipid and Polymer-Based Nanoparticle siRNA Delivery Systems for Cancer Therapy

Francesco Mainini et al.

MOLECULES (2020)

Article Multidisciplinary Sciences

Nanoparticle delivery of immunostimulatory oligonucleotides enhances response to checkpoint inhibitor therapeutics

Colin G. Buss et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Chemistry, Multidisciplinary

Manipulating the function of tumor-associated macrophages by siRNA-loaded lipid nanoparticles for cancer immunotherapy

Nour Shobaki et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Article Medicine, Research & Experimental

Far-reaching advances in the role of carbon nanotubes in cancer therapy

Babak Faraji Dizaji et al.

LIFE SCIENCES (2020)

Review Multidisciplinary Sciences

Concepts of extracellular matrix remodelling in tumour progression and metastasis

Juliane Winkler et al.

NATURE COMMUNICATIONS (2020)

Article Multidisciplinary Sciences

Nanoparticle-enhanced chemo-immunotherapy to trigger robust antitumor immunity

Jingjing Liang et al.

SCIENCE ADVANCES (2020)

Review Chemistry, Multidisciplinary

Nanoparticle Formulations of Poly (ADP-ribose) Polymerase Inhibitors for Cancer Therapy

Bijay Singh et al.

FRONTIERS IN CHEMISTRY (2020)

Review Oncology

Trial watch: TLR3 agonists in cancer therapy

Julie Le Naour et al.

ONCOIMMUNOLOGY (2020)

Review Biochemistry & Molecular Biology

Extracellular Matrix in the Tumor Microenvironment and Its Impact on Cancer Therapy

Erik Henke et al.

FRONTIERS IN MOLECULAR BIOSCIENCES (2020)

Review Biochemistry & Molecular Biology

The relationship between autophagy and the immune system and its applications for tumor immunotherapy

Guan-Min Jiang et al.

MOLECULAR CANCER (2019)

Article Chemistry, Multidisciplinary

Synergistic STING activation by PC7A nanovaccine and ionizing radiation improves cancer immunotherapy

Min Luo et al.

JOURNAL OF CONTROLLED RELEASE (2019)

Article Multidisciplinary Sciences

Regulation of antitumour CD8 T-cell immunity and checkpoint blockade immunotherapy by Neuropilin-1

Marine Leclerc et al.

NATURE COMMUNICATIONS (2019)

Review Immunology

The Remarkable Plasticity of Macrophages: A Chance to Fight Cancer

Nadege Bercovici et al.

FRONTIERS IN IMMUNOLOGY (2019)

Article Chemistry, Multidisciplinary

Collagenase Nanoparticles Enhance the Penetration of Drugs into Pancreatic Tumors

Assaf Zinger et al.

ACS NANO (2019)

Article Medicine, Research & Experimental

Enhanced penetration and cytotoxicity of metformin and collagenase conjugated gold nanoparticles in breast cancer spheroids

Elaheh Dalir Abdolahinia et al.

LIFE SCIENCES (2019)

Review Chemistry, Multidisciplinary

MicroRNA delivery through nanoparticles

Sharon Wei Ling Lee et al.

JOURNAL OF CONTROLLED RELEASE (2019)

Review Immunology

The Role of TLRs in Anti-cancer Immunity and Tumor Rejection

Zuzanna Urban-Wojciuk et al.

FRONTIERS IN IMMUNOLOGY (2019)

Review Oncology

Cytokines in clinical cancer immunotherapy

Pedro Berraondo et al.

BRITISH JOURNAL OF CANCER (2019)

Article Chemistry, Multidisciplinary

Efficient PD-L1 gene silence promoted by hyaluronidase for cancer immunotherapy

Xiuwen Guan et al.

JOURNAL OF CONTROLLED RELEASE (2019)

Review Biotechnology & Applied Microbiology

Approaches to treat immune hot, altered and cold tumours with combination immunotherapies

Jerome Galon et al.

NATURE REVIEWS DRUG DISCOVERY (2019)

Review Biochemistry & Molecular Biology

The ROMP: A Powerful Approach to Synthesize Novel pH-Sensitive Nanoparticles for Tumor Therapy

Philippe Bertrand et al.

BIOMOLECULES (2019)

Article Biotechnology & Applied Microbiology

Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery

Li Tang et al.

NATURE BIOTECHNOLOGY (2018)

Review Oncology

Targeting Macrophages in Cancer: From Bench to Bedside

Ashleigh R. Poh et al.

FRONTIERS IN ONCOLOGY (2018)

Article Engineering, Biomedical

TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy

Christopher B. Rodell et al.

NATURE BIOMEDICAL ENGINEERING (2018)

Review Pharmacology & Pharmacy

The Role of Toll-Like Receptor in Inflammation and Tumor Immunity

Xiaohong Cen et al.

FRONTIERS IN PHARMACOLOGY (2018)

Review Cell Biology

STING Signaling Promotes Apoptosis, Necrosis, and Cell Death: An Overview and Update

Song Liu et al.

MEDIATORS OF INFLAMMATION (2018)

Article Nanoscience & Nanotechnology

A STING-activating nanovaccine for cancer immunotherapy

Min Luo et al.

NATURE NANOTECHNOLOGY (2017)

Article Multidisciplinary Sciences

Targeting cancer cell integrins using gold nanorods in photothermal therapy inhibits migration through affecting cytoskeletal proteins

Moustafa R. K. Ali et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Oncology

The Damaging Effect of Passenger Mutations on Cancer Progression

Christopher D. McFarland et al.

CANCER RESEARCH (2017)

Article Pharmacology & Pharmacy

Drug delivery to the brain: how can nanoencapsulated statins be used in the clinic?

Fabio Sonvico et al.

THERAPEUTIC DELIVERY (2017)

Article Oncology

PDL1 Regulation by p53 via miR-34

Maria Angelica Cortez et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2016)

Article Oncology

PDL1 Regulation by p53 via miR-34

Maria Angelica Cortez et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2016)

Article Chemistry, Multidisciplinary

Rationally Designed 2-in-1 Nanoparticles Can Overcome Adaptive Resistance in Cancer

Aaron Goldman et al.

ACS NANO (2016)

Article Engineering, Biomedical

A prodrug-doped cellular Trojan Horse for the potential treatment of prostate cancer

Oren Levy et al.

BIOMATERIALS (2016)

Article Immunology

Tumor macrophages are pivotal constructors of tumor collagenous matrix

Ran Afik et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2016)

Review Multidisciplinary Sciences

T cell exclusion, immune privilege, and the tumor microenvironment

Johanna A. Joyce et al.

SCIENCE (2015)

Review Chemistry, Medicinal

Expanding the Therapeutic Potential of Statins by Means of Nanotechnology Enabled Drug Delivery Systems

Bilquis Romana et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2014)

Review Chemistry, Multidisciplinary

EPR: Evidence and fallacy

Joseph W. Nichols et al.

JOURNAL OF CONTROLLED RELEASE (2014)

Review Cell Biology

Remodelling the extracellular matrix in development and disease

Caroline Bonnans et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)

Review Oncology

Collagen as a double-edged sword in tumor progression

Min Fang et al.

TUMOR BIOLOGY (2014)

Article Biochemical Research Methods

The Matrisome: In Silico Definition and In Vivo Characterization by Proteomics of Normal and Tumor Extracellular Matrices

Alexandra Naba et al.

MOLECULAR & CELLULAR PROTEOMICS (2012)

Article Chemistry, Multidisciplinary

Inhibition of Mammary Tumor Growth Using Lysyl Oxidase-Targeting Nanoparticles to Modify Extracellular Matrix

Mathumai Kanapathipillai et al.

NANO LETTERS (2012)

Review Oncology

Molecular signatures suggest a major role for stromal cells in development of invasive breast cancer

Theresa Casey et al.

BREAST CANCER RESEARCH AND TREATMENT (2009)

Review Oncology

Toll-like receptors and cancer

Seth Rakoff-Nahoum et al.

NATURE REVIEWS CANCER (2009)

Review Oncology

High interstitial fluid pressure -: An obstacle in cancer therapy

CH Heldin et al.

NATURE REVIEWS CANCER (2004)

Review Pharmacology & Pharmacy

PEGylated nanoparticles for biological and pharmaceutical applications

H Otsuka et al.

ADVANCED DRUG DELIVERY REVIEWS (2003)