期刊
ENGINEERING
卷 12, 期 -, 页码 128-138出版社
ELSEVIER
DOI: 10.1016/j.eng.2021.03.021
关键词
Cronobacter; Food contamination; Pathogenesis; Virulence factors; Stress response
资金
- National Key Research and Development program, China [2017YFC1601202, 2017YFC1601200]
- China Postdoctoral Science Foundation [2021M690854]
- National Natural Science Foundation of China [31671951, 31972175]
- Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program [2017BT01S174]
- Fundamental Research Funds for the Central Universities, China [JZ2020HGQA0151]
This review summarizes the prevalence of Cronobacter species in various food types and highlights its high virulence in infants. The mechanisms allowing Cronobacter to persist in adverse growth conditions and its pathogenicity are discussed. The food safety concerns caused by Cronobacter and the subsequent control methods and clinical treatments are emphasized.
Cronobacter species are a group of Gram-negative opportunistic pathogens, which cause meningitis, septicemia, and necrotizing enterocolitis in neonates and infants, with neurological sequelae in severe cases. Interest in Cronobacter has increased significantly in recent years due to its high virulence in children. In this review, we summarize the current understanding of the prevalence of Cronobacter species in several important food types. We discuss the response mechanisms enabling persistence in adverse growth conditions, as well as its pathogenicity. We emphasize the food safety concerns caused by Cronobacter and subsequent control methods and clinical treatments. (C) 2021 The AUTHORS. Published by Elsevier LTD on behalf of Chinese Academy of Engineering and Higher Education Press Limited Company.
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