4.4 Review

A Review of Current Trends with Type 2 Diabetes Epidemiology, Aetiology, Pathogenesis, Treatments and Future Perspectives

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Endocrinology & Metabolism

A systematic review and meta-analysis of the impact of GLP-1 receptor agonists and SGLT-2 inhibitors on cardiovascular outcomes in biologically healthy older adults

William D. Strain et al.

Summary: A systematic review and meta-analysis showed that GLP-1 receptor agonists and SGLT-2 inhibitors were effective in reducing major adverse cardiovascular events (MACE) in older adults eligible for clinical trials. The use of these medications in older adults demonstrated a similar or even superior benefit compared to younger individuals, indicating potential positive impacts in clinical practice.

BRITISH JOURNAL OF DIABETES (2021)

Review Endocrinology & Metabolism

GLP-1 receptor agonists and SGLT2 inhibitors for older people with type 2 diabetes: A systematic review and meta-analysis

Thomas Karagiannis et al.

Summary: Both GLP-1 RAs and SGLT2 inhibitors have significant cardiovascular protective effects in older adults with type 2 diabetes, especially in reducing MACE. SGLT2 inhibitors also reduce heart failure and renal outcomes.

DIABETES RESEARCH AND CLINICAL PRACTICE (2021)

Review Endocrinology & Metabolism

GLP-1 receptor agonists: an updated review of head-to-head clinical studies

Jennifer M. Trujillo et al.

Summary: GLP-1 RA agents are effective in reducing A1C and weight for the treatment of type 2 diabetes, but there are differences in magnitude of effect and frequency of adverse effects among different agents in the class.

THERAPEUTIC ADVANCES IN ENDOCRINOLOGY AND METABOLISM (2021)

Review Chemistry, Multidisciplinary

Oral Insulin Delivery Platforms: Strategies To Address the Biological Barriers

Yufen Xiao et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Article Biotechnology & Applied Microbiology

Oral delivery of insulin with intelligent glucose-responsive switch for blood glucose regulation

Xia Zhou et al.

JOURNAL OF NANOBIOTECHNOLOGY (2020)

Article Pharmacology & Pharmacy

Oral Insulin Delivery Using Poly (Styrene Co-Maleic Acid) Micelles in a Diabetic Mouse Model

Fatemah Bahman et al.

PHARMACEUTICS (2020)

Article Biochemistry & Molecular Biology

Coagonist of GLP-1 and glucagon decreases liver inflammation and atherosclerosis in dyslipidemic condition

Vishal Patel et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2018)

Review Endocrinology & Metabolism

A review of GLP-1 receptor agonists: Evolution and advancement, through the lens of randomised controlled trials

Vanita R. Aroda

DIABETES OBESITY & METABOLISM (2018)

Article Medicine, General & Internal

Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes

Rury R. Holman et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Review Endocrinology & Metabolism

The role of bariatric surgery to treat diabetes: current challenges and perspectives

Chrysi Koliaki et al.

BMC ENDOCRINE DISORDERS (2017)

Review Endocrinology & Metabolism

The dynamic plasticity of insulin production in β-cells

Brandon B. Boland et al.

MOLECULAR METABOLISM (2017)

Review Multidisciplinary Sciences

Diabetic nephropathy: Time to withhold development and progression A review

Usama A. A. Sharaf El Din et al.

JOURNAL OF ADVANCED RESEARCH (2017)

Review Endocrinology & Metabolism

Glucagon-like peptide- I receptor agonists: a systematic review of comparative effectiveness research

Philip A. Levin et al.

DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY (2017)

Article Urology & Nephrology

Diabetic Kidney Disease Challenges, Progress, and Possibilities

Radica Z. Alicic et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)

Review Endocrinology & Metabolism

Diabetes after Bariatric Surgery

Ankit Shah et al.

CANADIAN JOURNAL OF DIABETES (2017)

Review Medicine, Research & Experimental

Diabetic retinopathy: current understanding, mechanisms, and treatment strategies

Elia J. Duh et al.

JCI INSIGHT (2017)

Review Gastroenterology & Hepatology

Which treatment for type 2 diabetes associated with non-alcoholic fatty liver disease?

Arianna Mazzotti et al.

DIGESTIVE AND LIVER DISEASE (2017)

Review Biochemistry & Molecular Biology

Mitochondrial involvement in skeletal muscle insulin resistance: A case of imbalanced bioenergetics

Charles Affourtit

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2016)

Review Medicine, Research & Experimental

Apoptosis in pancreatic beta-islet cells in Type 2 diabetes

Tatsuo Tomita

BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES (2016)

Article Endocrinology & Metabolism

Standards of care for type 2 diabetes in China

Jianping Weng et al.

DIABETES-METABOLISM RESEARCH AND REVIEWS (2016)

Review Endocrinology & Metabolism

Sex and Gender Differences in Risk, Pathophysiology and Complications of Type 2 Diabetes Mellitus

Alexandra Kautzky-Willer et al.

ENDOCRINE REVIEWS (2016)

Article Endocrinology & Metabolism

Decreased Hypothalamic Glucagon-Like Peptide-1 Receptor Expression in Type 2 Diabetes Patients

Jennifer S. ten Kulve et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2016)

Article Medicine, General & Internal

Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes

Steven P. Marso et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Medicine, General & Internal

Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes

Steven P. Marso et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Multidisciplinary Sciences

Altered Myokine Secretion Is an Intrinsic Property of Skeletal Muscle in Type 2 Diabetes

Theodore P. Ciaraldi et al.

PLOS ONE (2016)

Article Medicine, General & Internal

Evaluation of lorcaserin on progression of prediabetes to type 2 diabetes and reversion to euglycemia

Richard Nesto et al.

POSTGRADUATE MEDICINE (2016)

Review Endocrinology & Metabolism

Skin disorders in diabetes mellitus: an epidemiology and physiopathology review

Geisa Maria Campos de Macedo et al.

DIABETOLOGY & METABOLIC SYNDROME (2016)

Article Multidisciplinary Sciences

Clinical Efficacy of Stem Cell Therapy for Diabetes Mellitus: A Meta-Analysis

Ahmed El-Badawy et al.

PLOS ONE (2016)

Review Pharmacology & Pharmacy

Glucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic Successes

Chris de Graaf et al.

PHARMACOLOGICAL REVIEWS (2016)

Article Medicine, General & Internal

The Obesity Paradox in Type 2 Diabetes Mellitus: Relationship of Body Mass Index to Prognosis A Cohort Study

Pierluigi Costanzo et al.

ANNALS OF INTERNAL MEDICINE (2015)

Review Public, Environmental & Occupational Health

Stress and Type 2 Diabetes: A Review of How Stress Contributes to the Development of Type 2 Diabetes

Shona J. Kelly et al.

ANNUAL REVIEW OF PUBLIC HEALTH, VOL 36 (2015)

Review Cell Biology

Alpha-, Delta- and PP-cells: Are They the Architectural Cornerstones of Islet Structure and Co-ordination?

Melissa F. Brereton et al.

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2015)

Article Medicine, General & Internal

Lixisenatide in Patients with Type 2 Diabetes and Acute Coronary Syndrome

Marc A. Pfeffer et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Review Public, Environmental & Occupational Health

Epidemiology of and Risk Factors for Type 2 Diabetes in Egypt

Refaat Hegazi et al.

ANNALS OF GLOBAL HEALTH (2015)

Review Genetics & Heredity

Genetics of Type 2 Diabetes-Pitfalls and Possibilities

Rashmi B. Prasad et al.

Review Endocrinology & Metabolism

Pancreatic α-Cell Dysfunction in Type 2 Diabetes: Old Kids on the Block

Jun Sung Moon et al.

DIABETES & METABOLISM JOURNAL (2015)

Review Endocrinology & Metabolism

Urinary tract infections in patients with type 2 diabetes mellitus: review of prevalence, diagnosis, and management

Orna Nitzan et al.

DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY (2015)

Article Biochemistry & Molecular Biology

A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents

Brian Finan et al.

NATURE MEDICINE (2015)

Review Endocrinology & Metabolism

Lean diabetes mellitus: An emerging entity in the era of obesity

Amrutha Mary George et al.

WORLD JOURNAL OF DIABETES (2015)

Review Endocrinology & Metabolism

Prediabetes diagnosis and treatment: A review

Nidhi Bansal

WORLD JOURNAL OF DIABETES (2015)

Review Endocrinology & Metabolism

Neural regulation of pancreatic islet cell mass and function

B. Thorens

DIABETES OBESITY & METABOLISM (2014)

Article Endocrinology & Metabolism

Global estimates of diabetes prevalence for 2013 and projections for 2035

L. Guariguata et al.

DIABETES RESEARCH AND CLINICAL PRACTICE (2014)

Article Endocrinology & Metabolism

Type 2 Diabetes Mellitus and Hypertension: An Update

Guido Lastra et al.

ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA (2014)

Review Geriatrics & Gerontology

Autoimmune Aspects of Type 2 Diabetes Mellitus - A Mini-Review

Bianca K. Itariu et al.

GERONTOLOGY (2014)

Review Medicine, General & Internal

GLP-1 receptor agonists vs. DPP-4 inhibitors for type 2 diabetes: is one approach more successful or preferable than the other?

S. Brunton

INTERNATIONAL JOURNAL OF CLINICAL PRACTICE (2014)

Review Medicine, General & Internal

The importance of weight management in type 2 diabetes mellitus

J. P. H. Wilding

INTERNATIONAL JOURNAL OF CLINICAL PRACTICE (2014)

Article Endocrinology & Metabolism

Racial Differences In Peripheral Insulin Sensitivity and Mitochondrial Capacity in the Absence of Obesity

James P. DeLany et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2014)

Editorial Material Medicine, Research & Experimental

Islet amyloid and type 2 diabetes: overproduction or inadequate clearance and detoxification?

Dhananjay Gupta et al.

JOURNAL OF CLINICAL INVESTIGATION (2014)

Article Medicine, Research & Experimental

Human IAPP-induced pancreatic β cell toxicity and its regulation by autophagy

Nayumi Shigihara et al.

JOURNAL OF CLINICAL INVESTIGATION (2014)

Article Endocrinology & Metabolism

Lean versus obese diabetes mellitus patients in the United States minority population

Nathaniel J. Coleman et al.

JOURNAL OF DIABETES AND ITS COMPLICATIONS (2014)

Article Medicine, General & Internal

Type 1 diabetes

Mark A. Atkinson et al.

LANCET (2014)

Article Biochemistry & Molecular Biology

A potentiator of orthosteric ligand activity at GLP-1R acts via covalent modification

Whitney M. Nolte et al.

NATURE CHEMICAL BIOLOGY (2014)

Article Multidisciplinary Sciences

UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation

Angelo Vozza et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Multidisciplinary Sciences

Reversible changes in pancreatic islet structure and function produced by elevated blood glucose

Melissa F. Brereton et al.

NATURE COMMUNICATIONS (2014)

Review Nutrition & Dietetics

Pancreatic β-Cell Proliferation in Obesity

Amelia K. Linnemann et al.

ADVANCES IN NUTRITION (2014)

Article Microbiology

Impact of the gut microbiota on the development of obesity and type 2 diabetes mellitus

Isabel Moreno-Indias et al.

FRONTIERS IN MICROBIOLOGY (2014)

Review Endocrinology & Metabolism

Autonomic neuropathy in diabetes mellitus

Alberto Verrotti et al.

FRONTIERS IN ENDOCRINOLOGY (2014)

Review Endocrinology & Metabolism

Management of adult diabetic ketoacidosis

Aidar R. Gosmanov et al.

DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY (2014)

Review Endocrinology & Metabolism

Treatment of type 2 diabetes, lifestyle, GLP1 agonists and DPP4 inhibitors

Gerald H. Tomkin

WORLD JOURNAL OF DIABETES (2014)

Review Endocrinology & Metabolism

Hepatitis C virus infection and insulin resistance

Sandip K. Bose et al.

WORLD JOURNAL OF DIABETES (2014)

Article Multidisciplinary Sciences

Type 2 diabetes in East Asians: similarities and differences with populations in Europe and the United States

Ronald C. W. Ma et al.

YEAR IN DIABETES AND OBESITY (2013)

Article Endocrinology & Metabolism

Gender aspects in type 2 diabetes mellitus and cardiometabolic risk

Naveed Sattar

BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2013)

Article Chemistry, Medicinal

Recent progress and future options in the development of GLP-1 receptor agonists for the treatment of diabesity

Martin Lorenz et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)

Review Public, Environmental & Occupational Health

Prevalence and complications of diabetes mellitus in Northern Africa, a systematic review

Manouk Bos et al.

BMC PUBLIC HEALTH (2013)

Article Endocrinology & Metabolism

Clues from Bariatric Surgery: Reversing Insulin Resistance to Heal the Heart

Khaled Imad Khalaf et al.

CURRENT DIABETES REPORTS (2013)

Article Endocrinology & Metabolism

Deficiency of Mitochondria in Muscle Does Not Cause Insulin Resistance

John O. Holloszy

DIABETES (2013)

Review Endocrinology & Metabolism

Incretin dysfunction in type 2 diabetes: Clinical impact and future perspectives

B. Ahren

DIABETES & METABOLISM (2013)

Article Endocrinology & Metabolism

Guideline Approach to Therapy in Patients With Newly Diagnosed Type 2 Diabetes

Itamar Raz

DIABETES CARE (2013)

Article Endocrinology & Metabolism

Do GLP-1-Based Therapies Increase Cancer Risk?

Michael A. Nauck et al.

DIABETES CARE (2013)

Review Endocrinology & Metabolism

Type 2 Diabetes Etiology and reversibility

Roy Taylor

DIABETES CARE (2013)

Article Endocrinology & Metabolism

Obesity Paradox Does Exist

Vojtech Hainer et al.

DIABETES CARE (2013)

Editorial Material Public, Environmental & Occupational Health

Commentary: Sub-types of diabetes-what's new and what's not

Sarah H. Wild et al.

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2013)

Article Endocrinology & Metabolism

Pathogenesis of Prediabetes: Role of the Liver in Isolated Fasting Hyperglycemia and Combined Fasting and Postprandial Hyperglycemia

Rita Basu et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2013)

Review Physiology

MECHANISMS OF DIABETIC COMPLICATIONS

Josephine M. Forbes et al.

PHYSIOLOGICAL REVIEWS (2013)

Article Multidisciplinary Sciences

Relationships between Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes Mellitus

Tineke van de Weijer et al.

PLOS ONE (2013)

Article Cell Biology

Unimolecular Dual Incretins Maximize Metabolic Benefits in Rodents, Monkeys, and Humans

Brian Finan et al.

SCIENCE TRANSLATIONAL MEDICINE (2013)

Article Endocrinology & Metabolism

Beta Cell Dysfunction and Insulin Resistance

Marlon E. Cerf

Frontiers in Endocrinology (2013)

Review Emergency Medicine

Diabetic Ketoacidosis: A Review and Update

Gretchen Perilli et al.

CURRENT EMERGENCY AND HOSPITAL MEDICINE REPORTS (2013)

Article Endocrinology & Metabolism

Type 2 diabetes mellitus in children and adolescents

Thomas Reinehr

WORLD JOURNAL OF DIABETES (2013)

Review Endocrinology & Metabolism

Genetics of type 2 diabetes

Omar Ali

WORLD JOURNAL OF DIABETES (2013)

Article Endocrinology & Metabolism

Gastrointestinal complications of diabetes mellitus

Babu Krishnan et al.

WORLD JOURNAL OF DIABETES (2013)

Article Biochemistry & Molecular Biology

Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

Chutima Talchai et al.

Editorial Material Endocrinology & Metabolism

Inherited β-Cell Dysfunction in Lean Individuals With Type 2 Diabetes

Anne E. W. Mathews et al.

DIABETES (2012)

Editorial Material Endocrinology & Metabolism

Diabetes: Have We Got It All Wrong?

Barbara E. Corkey

DIABETES CARE (2012)

Article Endocrinology & Metabolism

Variation in the recorded incidence of amputation of the lower limb in England

N. Holman et al.

DIABETOLOGIA (2012)

Article Biochemistry & Molecular Biology

Glutathionylation State of Uncoupling Protein-2 and the Control of Glucose-stimulated Insulin Secretion

Ryan J. Mailloux et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Endocrinology & Metabolism

Decreased PTH Levels Accompanied by Low Bone Formation Are Associated with Vertebral Fractures in Postmenopausal Women with Type 2 Diabetes

Masahiro Yamamoto et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)

Review Cell Biology

The molecular mechanisms of pancreatic β-cell glucotoxicity: Recent findings and future research directions

Mohammed Bensellam et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2012)

Article Medicine, General & Internal

Prediabetes: a high-risk state for diabetes development

Adam G. Tabak et al.

LANCET (2012)

Review Endocrinology & Metabolism

The worldwide epidemiology of type 2 diabetes mellitus-present and future perspectives

Lei Chen et al.

NATURE REVIEWS ENDOCRINOLOGY (2012)

Article Endocrinology & Metabolism

Obesity Paradox in Amputation Risk Among Nonelderly Diabetic Men

Min-Woong Sohn et al.

OBESITY (2012)

Review Endocrinology & Metabolism

Mitochondrial proticity and ROS signaling: lessons from the uncoupling proteins

Ryan J. Mailloux et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2012)

Review Endocrinology & Metabolism

What causes the insulin resistance underlying obesity?

Olga T. Hardy et al.

CURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITY (2012)

Article Medicine, Research & Experimental

The Pathogenesis and Natural History of Type 1 Diabetes

Mark A. Atkinson

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)

Article Medicine, Research & Experimental

Genetics of Type 1 Diabetes

Janelle A. Noble et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)

Review Peripheral Vascular Disease

Hyperglycemia and Endothelial Dysfunction in Atherosclerosis: Lessons from Type 1 Diabetes

Steven Daniel Funk et al.

INTERNATIONAL JOURNAL OF VASCULAR MEDICINE (2012)

Article Endocrinology & Metabolism

Metabolic inflexibility is a common feature of impaired fasting glycaemia and impaired glucose tolerance

Kristine Faerch et al.

ACTA DIABETOLOGICA (2011)

Review Pharmacology & Pharmacy

Diabetes mellitus and Alzheimer's disease: shared pathology and treatment?

Kawser Akter et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2011)

Review Medical Laboratory Technology

Genetics of Type 2 Diabetes

Emma Ahlqvist et al.

CLINICAL CHEMISTRY (2011)

Article Endocrinology & Metabolism

Identification of Autoantibody-Negative Autoimmune Type 2 Diabetic Patients

Barbara M. Brooks-Worrell et al.

DIABETES CARE (2011)

Article Endocrinology & Metabolism

Incretin Effects on β-cell Function, Replication, and Mass The human perspective

Alan J. Garber

DIABETES CARE (2011)

Article Endocrinology & Metabolism

Type 2 Diabetes in Youth: Epidemiology and Pathophysiology

Ebe D'Adamo et al.

DIABETES CARE (2011)

Article Endocrinology & Metabolism

The role of dysregulated glucagon secretion in type 2 diabetes

D. D'Alessio

DIABETES OBESITY & METABOLISM (2011)

Article Endocrinology & Metabolism

Brain glucose sensing and neural regulation of insulin and glucagon secretion

B. Thorens

DIABETES OBESITY & METABOLISM (2011)

Article Endocrinology & Metabolism

The dual control of insulin secretion by glucose involves triggering and amplifying pathways in β-cells

Jean-Claude Henquin

DIABETES RESEARCH AND CLINICAL PRACTICE (2011)

Article Endocrinology & Metabolism

Insulin effects in muscle and adipose tissue

George Dimitriadis et al.

DIABETES RESEARCH AND CLINICAL PRACTICE (2011)

Review Endocrinology & Metabolism

Bariatric surgery for treatment of obesity

S. Eldar et al.

INTERNATIONAL JOURNAL OF OBESITY (2011)

Article Biochemistry & Molecular Biology

Glutathionylation Acts as a Control Switch for Uncoupling Proteins UCP2 and UCP3

Ryan J. Mailloux et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Review Endocrinology & Metabolism

Endocrine disruptors in the etiology of type 2 diabetes mellitus

Paloma Alonso-Magdalena et al.

NATURE REVIEWS ENDOCRINOLOGY (2011)

Review Endocrinology & Metabolism

β-cell mass in people with type 2 diabetes

Jae-Hyoung Cho et al.

JOURNAL OF DIABETES INVESTIGATION (2011)

Review Endocrinology & Metabolism

Mechanism of diabetic neuropathy: Where are we now and where to go?

Soroku Yagihashi et al.

JOURNAL OF DIABETES INVESTIGATION (2011)

Review Endocrinology & Metabolism

β-Cell failure in type 2 diabetes

Gil Leibowitz et al.

JOURNAL OF DIABETES INVESTIGATION (2011)

Review Endocrinology & Metabolism

Pathogenesis of diabetic nephropathy

Zemin Cao et al.

JOURNAL OF DIABETES INVESTIGATION (2011)

Review Endocrinology & Metabolism

Glucolipotoxicity in Pancreatic β-Cells

Ji-Won Kim et al.

DIABETES & METABOLISM JOURNAL (2011)

Review Critical Care Medicine

Clinical review: Ketones and brain injury

Hayden White et al.

CRITICAL CARE (2011)

Article Endocrinology & Metabolism

Congenital leptin deficiency: diagnosis and effects of leptin replacement therapy

Gilberto Paz-Filho et al.

ARQUIVOS BRASILEIROS DE ENDOCRINOLOGIA E METABOLOGIA (2010)

Review Biochemistry & Molecular Biology

Glucolipotoxicity of the pancreatic beta cell

Vincent Poitout et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2010)

Editorial Material Endocrinology & Metabolism

GIP: An Inconsequential Incretin or Not?

Richard E. Pratley

DIABETES CARE (2010)

Review Endocrinology & Metabolism

Incretin-Based Therapies for the Treatment of Type 2 Diabetes: Evaluation of the Risks and Benefits

Daniel J. Drucker et al.

DIABETES CARE (2010)

Review Endocrinology & Metabolism

Reactive oxygen species and uncoupling protein 2 in pancreatic beta-cell function

J. Pi et al.

DIABETES OBESITY & METABOLISM (2010)

Article Endocrinology & Metabolism

Global estimates of the prevalence of diabetes for 2010 and 2030

J. E. Shaw et al.

DIABETES RESEARCH AND CLINICAL PRACTICE (2010)

Article Endocrinology & Metabolism

Toll-like receptors regulate B cell cytokine production in patients with diabetes

M. Jagannathan et al.

DIABETOLOGIA (2010)

Article Endocrinology & Metabolism

Epidemiology of Type 1 Diabetes

David M. Maahs et al.

ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA (2010)

Article Gastroenterology & Hepatology

The Epidemiology of Obesity

Dang M. Nguyen et al.

GASTROENTEROLOGY CLINICS OF NORTH AMERICA (2010)

Review Endocrinology & Metabolism

Current views on type 2 diabetes

Yi Lin et al.

JOURNAL OF ENDOCRINOLOGY (2010)

Review Medicine, General & Internal

Risk of Cardiovascular Disease in Patients with Nonalcoholic Fatty Liver Disease

Giovanni Targher et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Review Pediatrics

The evolving place of incretin-based therapies in type 2 diabetes

Baptist Gallwitz

PEDIATRIC NEPHROLOGY (2010)

Review Endocrinology & Metabolism

Pancreatic islet plasticity Interspecies comparison of islet architecture and composition

Donald J. Steiner et al.

ISLETS (2010)

Review Endocrinology & Metabolism

GIP and GLP-1, the two incretin hormones: Similarities and differences

Yutaka Seino et al.

JOURNAL OF DIABETES INVESTIGATION (2010)

Editorial Material Endocrinology & Metabolism

Obesity and diabetes: the links and common approaches

David Haslam

PRIMARY CARE DIABETES (2010)

Review Biochemistry & Molecular Biology

A look inside the diabetic brain: Contributors to diabetes-induced brain aging

Shayna A. Wrighten et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2009)

Article Biochemistry & Molecular Biology

Nitric oxide and vascular insulin resistance

Guoyao Wu et al.

BIOFACTORS (2009)

Article Cell Biology

Insulin Signaling in α Cells Modulates Glucagon Secretion In Vivo

Dan Kawamori et al.

CELL METABOLISM (2009)

Article Endocrinology & Metabolism

Treating Diabetes and Prediabetes by Focusing on Obesity Management

Lalita Khaodhiar et al.

CURRENT DIABETES REPORTS (2009)

Article Endocrinology & Metabolism

Increased Risk of Type 2 Diabetes in Elderly Twins

Pernille Poulsen et al.

DIABETES (2009)

Article Endocrinology & Metabolism

Early Insulin Use in Type 2 Diabetes What are the cons?

Jean-Louis Chiasson

DIABETES CARE (2009)

Article Endocrinology & Metabolism

Skeletal Muscle Insulin Resistance Is the Primary Defect in Type 2 Diabetes

Ralph A. DeFronzo et al.

DIABETES CARE (2009)

Article Endocrinology & Metabolism

Excessive Loss of Skeletal Muscle Mass in Older Adults With Type 2 Diabetes

Seok Won Park et al.

DIABETES CARE (2009)

Article Endocrinology & Metabolism

Defining and Characterizing the Progression of Type 2 Diabetes

Vivian A. Fonseca

DIABETES CARE (2009)

Article Cardiac & Cardiovascular Systems

Development of life-expectancy tables for people with type 2 diabetes

Jose Leal et al.

EUROPEAN HEART JOURNAL (2009)

Review Primary Health Care

Secondary Hyperparathyroidism: Pathophysiology and Treatment

Wissam Saliba et al.

JOURNAL OF THE AMERICAN BOARD OF FAMILY MEDICINE (2009)

Article Endocrinology & Metabolism

Hepatic fat is not associated with β-cell function or postprandial free fatty acid response

Josina M. Rojkelijkhuizen et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2009)

Article Nutrition & Dietetics

Prevalence of nutrient deficiencies in bariatric patients

Seok Yee Toh et al.

NUTRITION (2009)

Article Cell & Tissue Engineering

Efficacy of Autologous Bone Marrow-Derived Stem Cell Transplantation in Patients With Type 2 Diabetes Mellitus

Anil Bhansali et al.

STEM CELLS AND DEVELOPMENT (2009)

Editorial Material Nutrition & Dietetics

Abdominal fat: does it predict the development of type 2 diabetes?

Amalia Gastaldelli

AMERICAN JOURNAL OF CLINICAL NUTRITION (2008)

Article Biochemistry & Molecular Biology

On the role of uncoupling protein-2 in pancreatic beta cells

Charles Affourtit et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2008)

Review Endocrinology & Metabolism

Hypoglycaemia in Type 2 diabetes

S. A. Amiel et al.

DIABETIC MEDICINE (2008)

Article Endocrinology & Metabolism

Pathogenesis of type 2 diabetes: tracing the reverse route from cure to cause

R. Taylor

DIABETOLOGIA (2008)

Review Cell Biology

Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes

Deborah M. Muoio et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)

Article Rehabilitation

The Spectrum of Diabetic Neuropathies

Jennifer A. Tracy et al.

PHYSICAL MEDICINE AND REHABILITATION CLINICS OF NORTH AMERICA (2008)

Article Psychology, Biological

Type 2 diabetes mellitus and skeletal muscle metabolic function

Esther Phielix et al.

PHYSIOLOGY & BEHAVIOR (2008)

Article Multidisciplinary Sciences

High-fat diets cause insulin resistance despite an increase in muscle mitochondria

Chad R. Hancock et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Review Physiology

The physiology of glucagon-like peptide 1

Jens Juul Holst

PHYSIOLOGICAL REVIEWS (2007)

Article Public, Environmental & Occupational Health

Hepatitis C virus lnfection and the development of type 2 diabetes in a community-based longitudinal study

Chong-Shan Wang et al.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2007)

Article Pharmacology & Pharmacy

Hyperglycemia and hyperlipidemia are associated with endothelial dysfunction during the development of type 2 diabetes

Elena B. Okon et al.

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2007)

Review Gastroenterology & Hepatology

Bariatric surgery: A review of procedures and outcomes

Katherine A. Elder et al.

GASTROENTEROLOGY (2007)

Article Endocrinology & Metabolism

Type 2 diabetes and the risk of Parkinson's disease

Gang Hu et al.

DIABETES CARE (2007)

Article Multidisciplinary Sciences

Small-molecule agonists for the glucagon-like peptide 1 receptor

Lotte Bjerre Knudsen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Review Cell Biology

The GLUT4 glucose transporter

Shaohui Huang et al.

CELL METABOLISM (2007)

Article Endocrinology & Metabolism

Type 2 diabetes mellitus in nursing home patients:: Effects on bone turnover, bone mass, and fracture risk

Harald Dobnig et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2006)

Letter Endocrinology & Metabolism

GLP-1/exendin-4 facilitates β-cell neogenesis in rat and human pancreatic ducts

Gang Xu et al.

DIABETES RESEARCH AND CLINICAL PRACTICE (2006)

Review Medicine, Research & Experimental

Islet β cell failure in type 2 diabetes

Marc Prentki et al.

JOURNAL OF CLINICAL INVESTIGATION (2006)

Letter Endocrinology & Metabolism

Seasonality in the incidence of type 2 diabetes - A population-based study

P Doro et al.

DIABETES CARE (2006)

Article Endocrinology & Metabolism

beta-cell function, insulin sensitivity, and glucose tolerance in obese diabetic and nondiabetic adolescents and young adults

DA Elder et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2006)

Article Veterinary Sciences

Islet amyloid polypeptide (IAPP) transgenic rodents as models for type 2 diabetes

Aleksey V. Matveyenko et al.

ILAR JOURNAL (2006)

Review Medicine, General & Internal

The medical complications of obesity

S. D. H. Malnick et al.

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE (2006)

Review Endocrinology & Metabolism

Parathyroid hormone: past and present

JT Potts

JOURNAL OF ENDOCRINOLOGY (2005)

Article Endocrinology & Metabolism

Link between obesity and type 2 diabetes

A Golay et al.

BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2005)

Review Medicine, Research & Experimental

Pathogenesis of type 2 diabetes mellitus

JL Leahy

ARCHIVES OF MEDICAL RESEARCH (2005)

Article Endocrinology & Metabolism

An association of Herpes simplex virus type 1 infection with type 2 diabetes

YH Sun et al.

DIABETES CARE (2005)

Article Endocrinology & Metabolism

Adiponectin: action, regulation and association to insulin sensitivity

AS Lihn et al.

OBESITY REVIEWS (2005)

Article Pharmacology & Pharmacy

Diabetic neuropathy: An intensive review

JJ Duby et al.

AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY (2004)

Article Endocrinology & Metabolism

Intramyocellular lipid content in type 2 diabetes patients compared with overweight sedentary men and highly trained endurance athletes

LJC van Loon et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2004)

Article Surgery

Bariatric surgery worldwide 2003

H Buchwald et al.

OBESITY SURGERY (2004)

Article Nutrition & Dietetics

Fatty acid metabolism in obesity and type 2 diabetes mellitus

EE Blaak

PROCEEDINGS OF THE NUTRITION SOCIETY (2003)

Article Endocrinology & Metabolism

beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

AE Butler et al.

DIABETES (2003)

Article Medicine, Research & Experimental

The diabetes-prone NZO/HILt strain. I. Immunophenotypic comparison to the related NZB/BINJ and NZW/LacJ strains

BD Haskell et al.

LABORATORY INVESTIGATION (2002)

Article Endocrinology & Metabolism

Impact of high-fat diet and antioxidant supplement on mitochondrial functions and gene transcripts in rat muscle

R Sreekumar et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2002)

Review Multidisciplinary Sciences

Biochemistry and molecular cell biology of diabetic complications

M Brownlee

NATURE (2001)

Article Nutrition & Dietetics

Adipose tissue and the insulin resistance syndrome

KN Frayn

PROCEEDINGS OF THE NUTRITION SOCIETY (2001)

Article Health Care Sciences & Services

Revisiting the oral glucose tolerance test criterion for the diagnosis of diabetes

MB Davidson et al.

JOURNAL OF GENERAL INTERNAL MEDICINE (2000)

Article Endocrinology & Metabolism

Evidence of islet cell autoimmunity in elderly patients with type 2 diabetes

M Pietropaolo et al.

DIABETES (2000)