4.7 Review

Advanced and Innovative Nano-Systems for Anticancer Targeted Drug Delivery

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Oncology

Targeting cancer cells with nanotherapeutics and nanodiagnostics: Current status and future perspectives

Eunus S. Ali et al.

Summary: Nanotechnology is reshaping healthcare strategies with a tremendous impact, especially in the fields of medical diagnostics and drug delivery, offering potential for improved effectiveness and sustainability in treating diseases like cancer. The application of nano-level elements can reduce drug toxicities and enhance drug delivery efficiency.

SEMINARS IN CANCER BIOLOGY (2021)

Article Oncology

Metabolic syndrome biomarkers and prostate cancer risk in theUKBiobank

Maria J. Monroy-Iglesias et al.

Summary: The study found no significant association between Metabolic Syndrome (MetS) and risk of prostate cancer (PCa), but a consistent inverse association was observed with the blood sugar indicator HbA1c. Mediation analysis revealed potential hormonal and inflammatory pathways which may influence this association.

INTERNATIONAL JOURNAL OF CANCER (2021)

Article Chemistry, Physical

Arginine-rich peptide/platinum hybrid colloid nanoparticle cluster: A single nanozyme mimicking multi-enzymatic cascade systems in peroxisome

Yan Liu et al.

Summary: This study presents the synthesis of arginine-rich peptide-Pt nanoparticle cluster (ARP-PtNC) nanozymes that mimic two typical enzymatic cascade systems found in natural peroxisomes. These nanozymes exhibit strong uricase-mimicking activity and scavenging capabilities for reactive oxygen species, with the potential to inhibit the formation of monosodium urate monohydrate, making them promising for gout and hyperuricemia therapy. The rational design of these hybrid nanozymes provides a versatile strategy to fabricate multi-enzymatic cascade systems, expanding the application of nanozymes in various fields.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2021)

Article Chemistry, Multidisciplinary

Biomimetic Nanoemulsion for Synergistic Photodynamic-Immunotherapy Against Hypoxic Breast Tumor

Yifan Zhang et al.

Summary: A novel biomimetic nanoemulsion camouflaged with a PD-1-expressing cell membrane was developed for synergistic photodynamic-immunotherapy against hypoxic breast tumors, effectively inhibiting tumor growth by boosting dendritic cell maturation and cytotoxic T lymphocyte infiltration.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Review Medicine, Research & Experimental

Nanomedicines: Redefining traditional medicine

Weijia Lu et al.

Summary: Nanomedicines provide a promising drug delivery system at the nanoscale to address the targeting and permeability issues of traditional drugs, yet their physical and chemical properties in vivo have not been fully explored. Factors such as metabolic pathways, safety concerns, and in vivo efficacy have prevented many nanomedicines from reaching clinical application.

BIOMEDICINE & PHARMACOTHERAPY (2021)

Article Chemistry, Multidisciplinary

Biomimetic Liposomal Nanoplatinum for Targeted Cancer Chemophototherapy

Xue-Liang Liu et al.

Summary: Nano-Pt loaded liposomal system enhances photodynamic therapy and chemotherapy in cancer treatment by increasing oxygen supply and releasing nanoparticles for better penetration, leading to inhibited tumor growth and extended survival without toxicity in animal models.

ADVANCED SCIENCE (2021)

Review Oncology

Regulation of Antitumor Immune Responses by Exosomes Derived from Tumor and Immune Cells

Andres Rincon-Riveros et al.

Summary: Extracellular vesicles, such as exosomes, have the potential to serve as biomarkers for cancer development, impacting various aspects of tumor progression and immune regulation.

CANCERS (2021)

Review Pharmacology & Pharmacy

Smart Stimuli-Responsive Liposomal Nanohybrid Systems: A Critical Review of Theranostic Behavior in Cancer

Jana K. Alwattar et al.

Summary: The era of nanotechnology has brought about novel research strategies in drug delivery, with liposomes and metal nanocarriers showing distinctive advantages but also limitations. By combining the criteria of both liposomes and metallic moieties, nanohybrid systems offer a promising approach for successful theranostic delivery, particularly in combating diseases like cancer.

PHARMACEUTICS (2021)

Review Cell Biology

Type III secreted effectors that target mitochondria

Ipsita Nandi et al.

Summary: Type III secretion system is utilized by Gram-negative bacterial pathogens to transport effectors into host cells. These effectors play a crucial role in virulence by manipulating host cell organelles, especially mitochondria. However, the mechanisms underlying the mitochondrial activity of type III secreted effectors are not yet fully understood.

CELLULAR MICROBIOLOGY (2021)

Review Biochemistry & Molecular Biology

Extracellular Vesicles Tune the Immune System in Renal Disease: A Focus on Systemic Lupus Erythematosus, Antiphospholipid Syndrome, Thrombotic Microangiopathy and ANCA-Vasculitis

Martina Mazzariol et al.

Summary: Extracellular vesicles play a crucial role in cell-to-cell communication and are involved in various diseases by modulating the immune system, coagulation cascade, angiogenetic process, and endothelial dysfunction. They have been investigated as potential biomarkers for renal injury and may have future applications as diagnostic and therapeutic tools in renal diseases.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Polymer Science

Dendron-Functionalized Polyglutamate-Pyropheophorbide-a Conjugates as Nanomedicines for Breast Cancer Photodynamic Therapy

Wenjia Wang et al.

Summary: A novel PGPD polymer conjugated with Ppa showed excellent solubility and self-assembly properties for effective PDT treatment of TNBC. The results demonstrated that PGPD induced ROS production and cell apoptosis in the animal model, possibly due to its enhanced delivery and accumulation efficiency at tumor sites compared to the linear control PGP.

MACROMOLECULAR RAPID COMMUNICATIONS (2021)

Article Multidisciplinary Sciences

Mitochondrion-specific dendritic lipopeptide liposomes for targeted sub-cellular delivery

Lei Jiang et al.

Summary: Mitochondria are key targets for photothermal and photodynamic treatment for cancer, but delivery of therapeutics to these organelles remains a challenge. In this study, authors developed a mitochondrial targeted liposomal delivery platform using a dendritic peptide moiety as a mitochondria targeting moiety and demonstrated its targeting and antitumour efficacy in a mouse model of breast cancer.

NATURE COMMUNICATIONS (2021)

Article Multidisciplinary Sciences

Co-delivery of IOX1 and doxorubicin for antibody-independent cancer chemo-immunotherapy

Jing Liu et al.

Summary: In this study, it was found that the histone demethylase inhibitor 5-carboxy-8-hydroxyquinoline (IOX1) reduces PD-L1 expression in cancer cells and enhances doxorubicin-induced immunogenic cell death, promoting T cell infiltration and reducing tumor growth in preclinical models.

NATURE COMMUNICATIONS (2021)

Article Multidisciplinary Sciences

Ultrasound-triggered herceptin liposomes for breast cancer therapy

Amal Elamir et al.

Summary: Functionalizing liposomes with monoclonal antibodies, particularly anti-HER2 antibodies, can enhance targeted drug delivery to HER2 positive breast cancer cells. Low frequency ultrasound (LFUS) triggered drug release from liposomes can be further enhanced by the conjugation of Trastuzumab, increasing drug uptake and cellular toxicity in HER2+ cell lines. Combining immunoliposomes with LFUS is a promising technique to improve drug delivery efficiency and reduce cytotoxicity of antineoplastic drugs.

SCIENTIFIC REPORTS (2021)

Article Cell Biology

Lysine 53 Acetylation of Cytochrome c in Prostate Cancer: Warburg Metabolism and Evasion of Apoptosis

Viktoriia Bazylianska et al.

Summary: The study reveals acetylation of cytochrome c at lysine 53 in prostate cancer cells, which affects cellular respiration and apoptosis, ultimately influencing cancer cell survival and growth.
Review Oncology

Triggered Drug Release From Liposomes: Exploiting the Outer and Inner Tumor Environment

Marina Santiago Franco et al.

Summary: Research has shown that liposomes can serve as potential carriers of anticancer drugs, accumulating passively in the tumor tissue by taking advantage of its characteristics. Different strategies, such as PEGylation and attaching ligands to the liposomal surface, have been employed to improve efficacy.

FRONTIERS IN ONCOLOGY (2021)

Article Biochemistry & Molecular Biology

Novel ginsenoside derivatives have shown their effects on PC-3 cells by inducing G1-phase arrest and reactive oxygen species-mediate cell apoptosis

Shengnan Xiao et al.

Summary: In this study, piperazine groups were introduced into ginsenoside to enhance its ability to induce Reactive Oxygen Species (ROS) production and apoptosis in cancer cells. A total of 27 ginsenoside piperazine derivatives were synthesized and tested for their anti-proliferative activity in cancer cell lines, with compound 6g showing the strongest inhibitory effect on PC-3 cells and inducing apoptosis through ROS production and mitochondrial pathway.

BIOORGANIC CHEMISTRY (2021)

Article Biophysics

Ruthenium(II)-curcumin liposome nanoparticles: Synthesis, characterization, and their effects against cervical cancer

Buddolla Anantha Lakshmi et al.

Summary: Ruthenium-based metal complexes incorporating curcumin were synthesized, loaded into liposomes to form Ru-Cur loaded liposome nanoparticles (RCLNPs), and demonstrated significant anticancer properties in cervical cancer cells.

COLLOIDS AND SURFACES B-BIOINTERFACES (2021)

Review Pharmacology & Pharmacy

An update on actively targeted liposomes in advanced drug delivery to glioma

Solmaz Mojarad-Jabali et al.

Summary: High-grade glioma is an aggressive type of cancer with a low survival rate, conventional chemotherapy faces challenges in delivering therapeutic dosage due to barriers in the brain, while surface modification of liposomes has shown promising results in improving drug delivery to glioma cells.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

Article Chemistry, Multidisciplinary

Synthetic infrared nano-photosensitizers with hierarchical zoom-in target-delivery functionalities for precision photodynamic therapy

Jing Xia et al.

Summary: The study presents a novel near-infrared PDT construct for efficient cancer treatment by surgical targeting vulnerable subcellular organelles with photodynamic therapy. The construct exhibited tumor-targeting and mitochondria-targeting capabilities, utilizing charge reversal chemistry responsive to acidic tumor microenvironments for preferential uptake. By exciting tissue-penetrating NIR and energy transfer mechanisms, complete tumor eradication was achieved through systemic administration of the multifunctional NIR photodynamic construct.

JOURNAL OF CONTROLLED RELEASE (2021)

Article Oncology

LDL, HDL and endocrine-related cancer: From pathogenic mechanisms to therapies

Giovanna Revilla et al.

Summary: Cholesterol is crucial for various functions in endocrine-related cells, including hormone and steroid production. While LDL-cholesterol and HDL-cholesterol were not consistently associated with endocrine-related cancer risk, LDL receptor plays a critical role in endocrine-related tumor cells by enhancing circulating LDL-C uptake.

SEMINARS IN CANCER BIOLOGY (2021)

Review Nanoscience & Nanotechnology

Liposomal Nanomedicine: Applications for Drug Delivery in Cancer Therapy

Foad Rommasi et al.

Summary: The increasing prevalence of cancer is a serious concern for scientists and physicians. Effective cancer treatment remains a major challenge in the health and medicine field, with drug therapies often facing barriers such as adverse effects and lack of specificity and sensitivity.

NANOSCALE RESEARCH LETTERS (2021)

Article Pharmacology & Pharmacy

Lysosome activable polymeric vorinostat encapsulating PD-L1KD for a combination of HDACi and immunotherapy

Fengkun Lu et al.

Summary: Studies have shown that the combination of epigenetic therapy and PD-1/PD-L1 blockade therapy can reverse immune escape, while lysosome activable polymeric vorinostat encapsulating PD-L1KD for the combination therapy of PD-L1-KD and HDACIs is an effective strategy to activate the immune system, inhibit tumor growth, and metastasis.

DRUG DELIVERY (2021)

Article Materials Science, Biomaterials

Fabrication of PεCL-AuNP-BSA core-shell-corona nanoparticles for flexible spatiotemporal drug delivery and SERS detection

Yanhang Hong et al.

Summary: This research successfully fabricated nanoparticles with poly(epsilon-caprolactone) cores, gold nanoparticle shells, and bovine serum albumin coronae through a self-assembly approach. The potential applications of these hybrid nanoparticles in drug delivery and surface-enhanced Raman scattering were demonstrated. The findings suggest that these hybrid nanoparticles have promising prospects for facilitating drug release and cellular uptake.

BIOMATERIALS SCIENCE (2021)

Review Materials Science, Biomaterials

Reconstituted high density lipoprotein (rHDL), a versatile drug delivery nanoplatform for tumor targeted therapy

Yijun Mei et al.

Summary: rHDL is a synthesized drug delivery nanoplatform with excellent biocompatibility and active-targeting ability, which improves the therapeutic effect of antitumor drugs.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

Article Biochemistry & Molecular Biology

Nitric oxide and peroxynitrite trigger and enhance release of neutrophil extracellular traps

Aneta Manda-Handzlik et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2020)

Review Multidisciplinary Sciences

The biology, function, and biomedical applications of exosomes

Raghu Kalluri et al.

SCIENCE (2020)

Article Nanoscience & Nanotechnology

pH-Responsive Artesunate Polymer Prodrugs with Enhanced Ablation Effect on Rodent Xenograft Colon Cancer

Dan-Li Hao et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)

Article Endocrinology & Metabolism

Regulation of hepatic glutamine metabolism by miR-122

Dipanwita Sengupta et al.

MOLECULAR METABOLISM (2020)

Review Pharmacology & Pharmacy

Nanogel: A Versatile Nano-Delivery System for Biomedical Applications

Yanlong Yin et al.

PHARMACEUTICS (2020)

Article Pharmacology & Pharmacy

Targeting efficiency of nanoliposomes on atherosclerotic foam cells: polyethylene glycol-to-ligand ratio effects

Anastasia Darwitan et al.

EXPERT OPINION ON DRUG DELIVERY (2020)

Article Biochemistry & Molecular Biology

Clusters of Circulating let-7 Family Tumor Suppressors Are Associated with Clinical Characteristics of Chronic Hepatitis C

Yi-Shan Tsai et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Biochemistry & Molecular Biology

Self-assembly of surfactants: An overview on general aspects of amphiphiles

Sampad Ghosh et al.

BIOPHYSICAL CHEMISTRY (2020)

Review Pharmacology & Pharmacy

Recent developments in stimuli-responsive polymer nanogels for drug delivery and diagnostics: A review

Namitha K. Preman et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2020)

Review Chemistry, Multidisciplinary

Doxorubicin-loaded composite nanogels for cancer treatment

Marzieh Mohammadi et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Review Nanoscience & Nanotechnology

Lipid-polymer hybrid nanoparticles as a next-generation drug delivery platform: state of the art, emerging technologies, and perspectives

Anubhab Mukherjee et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

Article Medicine, General & Internal

MiR-122 Targets SerpinB3 and Is Involved in Sorafenib Resistance in Hepatocellular Carcinoma

Cristian Turato et al.

JOURNAL OF CLINICAL MEDICINE (2019)

Article Chemistry, Physical

Analytical modeling of micelle growth. 1. Chain-conformation free energy of binary mixed spherical, wormlike and lamellar micelles

Krassimir D. Danov et al.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2019)

Article Biochemistry & Molecular Biology

Identifying and targeting angiogenesis-related microRNAs in ovarian cancer

Xiuhui Chen et al.

ONCOGENE (2019)

Review Materials Science, Multidisciplinary

PEGylated liposomes: immunological responses

Marwa Mohamed et al.

SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS (2019)

Review Chemistry, Multidisciplinary

Current Applications of Nanoemulsions in Cancer Therapeutics

Elena Sanchez-Lopez et al.

NANOMATERIALS (2019)

Review Pharmacology & Pharmacy

Current advances in BCG-unresponsive non-muscle invasive bladder cancer

Jennifer Tse et al.

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2019)

Article Biochemistry & Molecular Biology

Biodegradable reduction-responsive polymeric micelles for enhanced delivery of melphalan to retinoblastoma cells

Jia Li et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Article Biochemistry & Molecular Biology

Mesenchymal stem cells-curcumin loaded chitosan nanoparticles hybrid vectors for tumor-tropic therapy

Menglu Xu et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Article Biochemistry & Molecular Biology

Oxidation of methionine residues in human apolipoprotein A-I generates a potent pro-inflammatory molecule

Andrzej Witkowski et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2019)

Review Nanoscience & Nanotechnology

Nanoparticle-Based Drug Delivery Systems for Enhanced Tumor-Targeting Treatment

Yanan Li et al.

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2019)

Review Biochemistry & Molecular Biology

Polyglycerol Hyperbranched Polyesters: Synthesis, Properties and Pharmaceutical and Biomedical Applications

Alexandra Zamboulis et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Biotechnology & Applied Microbiology

Approaches to treat immune hot, altered and cold tumours with combination immunotherapies

Jerome Galon et al.

NATURE REVIEWS DRUG DISCOVERY (2019)

Review Oncology

Exosomes in cancer development and clinical applications

Yu-Ling Tai et al.

CANCER SCIENCE (2018)

Review Pharmacology & Pharmacy

High-density Lipoprotein (HDL) Dysfunction and the Future of HDL

Sibel Ertek

CURRENT VASCULAR PHARMACOLOGY (2018)

Review Pharmacology & Pharmacy

Nanogels as potential drug nanocarriers for CNS drug delivery

Arti Vashist et al.

DRUG DISCOVERY TODAY (2018)

Review Pharmacology & Pharmacy

Bioresponsive functional nanogels as an emerging platform for cancer therapy

Dechun Huang et al.

EXPERT OPINION ON DRUG DELIVERY (2018)

Article Biochemistry & Molecular Biology

In vitro neuroprotective effects of naringenin nanoemulsion against β-amyloid toxicity through the regulation of amyloidogenesis and tau phosphorylation

Shadab Md et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

Article Cell Biology

Exosomes originating from MSCs stimulated with TGF- and IFN- promote Treg differentiation

Qingyi Zhang et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2018)

Article Chemistry, Multidisciplinary

Bioreduction-ruptured nanogel for switch on/off release of Bcl2 siRNA in breast tumor therapy

Huipeng Li et al.

JOURNAL OF CONTROLLED RELEASE (2018)

Review Genetics & Heredity

Current Transport Systems and Clinical Applications for Small Interfering RNA (siRNA) Drugs

Fang Liu et al.

MOLECULAR DIAGNOSIS & THERAPY (2018)

Article Multidisciplinary Sciences

TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis

Daniele V. F. Tauriello et al.

NATURE (2018)

Review Gastroenterology & Hepatology

Therapeutic developments in pancreatic cancer: current and future perspectives

John P. Neoptolemos et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2018)

Review Multidisciplinary Sciences

Cancer immunotherapy using checkpoint blockade

Antoni Ribas et al.

SCIENCE (2018)

Article Materials Science, Biomaterials

Environment-stimulated nanocarriers enabling multi-active sites for high drug encapsulation as an on demand'' drug release system

F. R. Cheng et al.

JOURNAL OF MATERIALS CHEMISTRY B (2018)

Article Multidisciplinary Sciences

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells

Sanjeev Mariathasan et al.

NATURE (2018)

Review Biotechnology & Applied Microbiology

Nano based drug delivery systems: recent developments and future prospects

Jayanta Kumar Patra et al.

JOURNAL OF NANOBIOTECHNOLOGY (2018)

Review Pharmacology & Pharmacy

Exosomes and Exosome-Inspired Vesicles for Targeted Drug Delivery

Sophia G. Antimisiaris et al.

PHARMACEUTICS (2018)

Article Nanoscience & Nanotechnology

Superparamagnetic reconstituted high-density lipoprotein nanocarriers for magnetically guided drug delivery

Sarika Sabnis et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2017)

Review Chemistry, Multidisciplinary

Nanogels for intracellular delivery of biotherapeutics

Dandan Li et al.

JOURNAL OF CONTROLLED RELEASE (2017)

Review Chemistry, Multidisciplinary

Nanoemulsion: Concepts, development and applications in drug delivery

Yuvraj Singh et al.

JOURNAL OF CONTROLLED RELEASE (2017)

Article Biochemistry & Molecular Biology

Photodynamic therapy mediated by acai oil (Euterpe oleracea Martius) in nanoemulsion: A potential treatment for melanoma

Victoria Monge-Fuentes et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2017)

Review Medicine, Research & Experimental

Lipid-Drug Conjugate for Enhancing Drug Delivery

Danielle Irby et al.

MOLECULAR PHARMACEUTICS (2017)

Review Oncology

The role of exosomes in cancer metastasis

Teresa Bernadette Steinbichler et al.

SEMINARS IN CANCER BIOLOGY (2017)

Review Nanoscience & Nanotechnology

Stimuli-responsive liposomes for drug delivery

Y. Lee et al.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2017)

Review Nanoscience & Nanotechnology

External triggering and triggered targeting strategies for drug delivery

Yanfei Wang et al.

NATURE REVIEWS MATERIALS (2017)

Review Chemistry, Multidisciplinary

Engineering exosomes as refined biological nanoplatforms for drug delivery

Xin Luan et al.

ACTA PHARMACOLOGICA SINICA (2017)

Review Chemistry, Medicinal

Advances in Micelle-based Drug Delivery: Cross-linked Systems

Ismail Alper Isoglu et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2017)

Review Pharmacology & Pharmacy

Pharmacokinetic and Pharmacodynamic Features of Nanoemulsion Following Oral, Intravenous, Topical and Nasal Route

Hira Choudhury et al.

CURRENT PHARMACEUTICAL DESIGN (2017)

Review Pharmacology & Pharmacy

Nanocarriers for cancer-targeted drug delivery

Preeti Kumari et al.

JOURNAL OF DRUG TARGETING (2016)

Review Chemistry, Multidisciplinary

High-Density Lipoproteins: Nature's Multifunctional Nanoparticles

Rui Kuai et al.

ACS NANO (2016)

Article Chemistry, Physical

Inorganic/polymer hybrid nanoparticles for sensing applications

Benjamin Sierra-Martin et al.

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2016)

Article Environmental Sciences

CRITICAL MICELLE CONCENTRATION VALUES FOR DIFFERENT SURFACTANTS MEASURED WITH SOLID-PHASE MICROEXTRACTION FIBERS

Joris J. -H. Haftka et al.

ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2016)

Review Materials Science, Biomaterials

New progress and prospects: The application of nanogel in drug delivery

Hui Zhang et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2016)

Article Biotechnology & Applied Microbiology

Exosomes increase the therapeutic index of doxorubicin in breast and ovarian cancer mouse models

Mohamad Hadla et al.

NANOMEDICINE (2016)

Review Pharmacology & Pharmacy

Nanoparticles for Cancer Targeting: Current and Future Directions

Suryakanta Swain et al.

CURRENT DRUG DELIVERY (2016)

Review Biochemical Research Methods

Dendrimers in Medicine: Therapeutic Concepts and Pharmaceutical Challenges

Lin-ping Wu et al.

BIOCONJUGATE CHEMISTRY (2015)

Article Engineering, Biomedical

Dual-functional bio-derived nanoparticulates for apoptotic antitumor therapy

Yang Ding et al.

BIOMATERIALS (2015)

Review Chemistry, Multidisciplinary

Biodegradable Polymer Nanogels for Drug/Nucleic Acid Delivery

Yulin Li et al.

CHEMICAL REVIEWS (2015)

Review Pharmacology & Pharmacy

Advanced targeted therapies in cancer: Drug nanocarriers, the future of chemotherapy

Edgar Perez-Herrero et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2015)

Article Chemistry, Multidisciplinary

Using exosomes, naturally-equipped nanocarriers, for drug delivery

Elena V. Batrakova et al.

JOURNAL OF CONTROLLED RELEASE (2015)

Review Biotechnology & Applied Microbiology

Dendrimer-nanoparticle conjugates in nanomedicine

Audrey Parat et al.

NANOMEDICINE (2015)

Article Chemistry, Multidisciplinary

Exosome Delivered Anticancer Drugs Across the Blood-Brain Barrier for Brain Cancer Therapy in Danio Rerio

Tianzhi Yang et al.

PHARMACEUTICAL RESEARCH (2015)

Article Multidisciplinary Sciences

Long-circulating siRNA nanoparticles for validating Prohibitin1-targeted non-small cell lung cancer treatment

Xi Zhu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Review Multidisciplinary Sciences

The future of immune checkpoint therapy

Padmanee Sharma et al.

SCIENCE (2015)

Review Multidisciplinary Sciences

Hydrogel: Preparation, characterization, and applications: A review

Enas M. Ahmed

JOURNAL OF ADVANCED RESEARCH (2015)

Review Biotechnology & Applied Microbiology

Stimuli-sensitive Systems-an emerging delivery system for drugs

Ankur Bhardwaj et al.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2015)

Review Biotechnology & Applied Microbiology

Nanoemulsion: an advanced mode of drug delivery system

Manjit Jaiswal et al.

3 BIOTECH (2015)

Review Pharmacology & Pharmacy

Nanoemulsions in Translational Research-Opportunities and Challenges in Targeted Cancer Therapy

Srinivas Ganta et al.

AAPS PHARMSCITECH (2014)

Review Pharmacology & Pharmacy

Nanopreparations for organelle-specific delivery in cancer

Swati Biswas et al.

ADVANCED DRUG DELIVERY REVIEWS (2014)

Article Chemistry, Multidisciplinary

Integration of Nanoassembly Functions for an Effective Delivery Cascade for Cancer Drugs

Qihang Sun et al.

ADVANCED MATERIALS (2014)

Review Cell Biology

Extracellular membrane vesicles as a mechanism of cell-to-cell communication: advantages and disadvantages

Giuseppina Turturici et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2014)

Article Nanoscience & Nanotechnology

Star-Shaped Polycaprolactone-Polyethyleneglycol Copolymer Micelle-Like Nanoparticles for Picropodophyllin Delivery

Jing Zhao et al.

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2014)

Review Pharmacology & Pharmacy

Mesenchymal stem cell: An efficient mass producer of exosomes for drug delivery

Ronne Wee Yeh Yeo et al.

ADVANCED DRUG DELIVERY REVIEWS (2013)

Review Chemistry, Multidisciplinary

The development of synthetic antitumour vaccines from mucin glycopeptide antigens

Nikola Gaidzik et al.

CHEMICAL SOCIETY REVIEWS (2013)

Article Biotechnology & Applied Microbiology

Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells

Shin-ichiro Ohno et al.

MOLECULAR THERAPY (2013)

Article Biochemistry & Molecular Biology

Cancer-Targeting Multifunctionalized Gold Nanoparticles in Imaging and Therapy

P. F. Jiao et al.

CURRENT MEDICINAL CHEMISTRY (2012)

Article Chemistry, Multidisciplinary

Differentially Charged Hollow Core/Shell Lipid-Polymer-Lipid Hybrid Nanoparticles for Small Interfering RNA Delivery

Jinjun Shi et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)

Review Biotechnology & Applied Microbiology

Bio-inspired, bioengineered and biomimetic drug delivery carriers

Jin-Wook Yoo et al.

NATURE REVIEWS DRUG DISCOVERY (2011)

Review Toxicology

Toxicity of the antimalarial artemisinin and its dervatives

Thomas Efferth et al.

CRITICAL REVIEWS IN TOXICOLOGY (2010)

Article Pharmacology & Pharmacy

Anti-PEG IgM Response against PEGylated Liposomes in Mice and Rats

Masako Ichihara et al.

Pharmaceutics (2010)

Review Biochemistry & Molecular Biology

Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction

Ji Luo et al.

Review Nanoscience & Nanotechnology

Nanocarriers as an emerging platform for cancer therapy

Dan Peer et al.

NATURE NANOTECHNOLOGY (2007)

Article Pharmacology & Pharmacy

Polymeric micelles for drug delivery

S. R. Croy et al.

CURRENT PHARMACEUTICAL DESIGN (2006)

Review Pharmacology & Pharmacy

Cell-penetrating peptides:: mechanism and kinetics of cargo delivery

M Zorko et al.

ADVANCED DRUG DELIVERY REVIEWS (2005)

Review Biochemistry & Molecular Biology

siRNA therapeutics: Big potential from small RNAs

RCC Ryther et al.

GENE THERAPY (2005)

Article Chemistry, Physical

Oxidation-responsive polymeric vesicles

A Napoli et al.

NATURE MATERIALS (2004)