期刊
CELLS
卷 10, 期 8, 页码 -出版社
MDPI
DOI: 10.3390/cells10082030
关键词
the hedgehog pathway; chemotherapy; resistance; gastric cancer; colorectal cancer; pancreatic cancer
类别
资金
- Well Center for Pediatric Research
- Jeff Gordon Research Laboratory
- AGA
- Healthcare Initiatives, Inc.
- CTSI Indiana
- National Natural Science Foundation of China [31960153]
This review focuses on the recent advances in the roles of the hedgehog pathway in drug resistance of gastrointestinal cancers and the novel drugs and strategies targeting hedgehog signaling.
The hedgehog pathway, which plays a significant role in embryonic development and stem cell regulation, is activated in gastrointestinal cancers. Chemotherapy is widely used in cancer treatment. However, chemoresistance becomes a substantial obstacle in cancer therapy. This review focuses on the recent advances in the hedgehog pathway's roles in drug resistance of gastrointestinal cancers and the novel drugs and strategies targeting hedgehog signaling.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据