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Djuro Kosanovic et al.
EUROPEAN RESPIRATORY JOURNAL (2015)
Mast cell stabilization with sodium cromoglycate modulates pulmonary vessel wall remodeling during four-day hypoxia in rats
Tomas Novotny et al.
EXPERIMENTAL LUNG RESEARCH (2015)
Histamine Induces Vascular Hyperpermeability by Increasing Blood Flow and Endothelial Barrier Disruption In Vivo
Kohei Ashina et al.
PLOS ONE (2015)
Rho-kinase regulates human platelet activation induced by thromboxane A2 independently of p38 MAP kinase
Yuko Iida et al.
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2015)
The Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular Disease
Svenja Hartmann et al.
FRONTIERS IN PHARMACOLOGY (2015)
Mechanical stretch-induced vascular hypertrophy occurs through modulation of leptin synthesis-mediated ROS formation and GATA-4 nuclear translocation
Crystal M. Ghantous et al.
FRONTIERS IN PHARMACOLOGY (2015)
The Rho Kinases: Critical Mediators of Multiple Profibrotic Processes and Rational Targets for New Therapies for Pulmonary Fibrosis
Rachel S. Knipe et al.
PHARMACOLOGICAL REVIEWS (2015)
RhoA/ROCK downregulates FPR2-mediated NADPH oxidase activation in mouse bone marrow granulocytes
Julia V. Filina et al.
CELLULAR SIGNALLING (2014)
Advances in Therapeutic Interventions for Patients With Pulmonary Arterial Hypertension
Marc Humbert et al.
CIRCULATION (2014)
Inflammation and Immunity in the Pathogenesis of Pulmonary Arterial Hypertension
Marlene Rabinovitch et al.
CIRCULATION RESEARCH (2014)
Acute hemodynamic response of infused fasudil in patients with pulmonary arterial hypertension: A randomized, controlled, crossover study
Xin Jiang et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2014)
Rho-Kinase Activation in Leukocytes Plays a Pivotal Role in Myocardial Ischemia/Reperfusion Injury
Katsunori Kitano et al.
PLOS ONE (2014)
Fasudil reversed MCT-induced and chronic hypoxia-induced pulmonary hypertension by attenuating oxidative stress and inhibiting the expression of Trx1 and HIF-1α
Manling Liu et al.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2014)
Possible role of lysophosphatidic acid in rat model of hypoxic pulmonary vascular remodeling
Vadim Shlyonsky et al.
PULMONARY CIRCULATION (2014)
Histological characterization of mast cell chymase in patients with pulmonary hypertension and chronic obstructive pulmonary disease
Djuro Kosanovic et al.
PULMONARY CIRCULATION (2014)
Crucial Role of ROCK2 in Vascular Smooth Muscle Cells for Hypoxia-Induced Pulmonary Hypertension in Mice
Toru Shimizu et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2013)
NHERF2 is crucial in ERM phosphorylation in pulmonary endothelial cells
Anita Boratko et al.
CELL COMMUNICATION AND SIGNALING (2013)
Double-Blind, Placebo-Controlled Clinical Trial With a Rho-Kinase Inhibitor in Pulmonary Arterial Hypertension - A Pilot Efficacy Trial -
Yoshihiro Fukumoto et al.
CIRCULATION JOURNAL (2013)
Epidemiology of Pulmonary Arterial Hypertension
Darren B. Taichman et al.
CLINICS IN CHEST MEDICINE (2013)
Advances in the studies of roles of Rho/Rho-kinase in diseases and the development of its inhibitors
Ronggui Guan et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
Simvastatin abrogates inflamed neutrophil adhesive properties, in association with the inhibition of Mac-1 integrin expression and modulation of Rho kinase activity
Angelica Aparecida Antoniellis Silveira et al.
INFLAMMATION RESEARCH (2013)
Role of Rho-kinase and its inhibitors in pulmonary hypertension
Sy Duong-Quy et al.
PHARMACOLOGY & THERAPEUTICS (2013)
Pathology and Pathobiology of Pulmonary Hypertension
Christophe Guignabert et al.
SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE (2013)
Immune and Inflammatory Cell Involvement in the Pathology of Idiopathic Pulmonary Arterial Hypertension
Rajkumar Savai et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2012)
Mast Cell Inhibition Improves Pulmonary Vascular Remodeling in Pulmonary Hypertension
Beatrijs Bartelds et al.
CHEST (2012)
PAR-2 Inhibition Reverses Experimental Pulmonary Hypertension
Grazyna Kwapiszewska et al.
CIRCULATION RESEARCH (2012)
Mast Cell Number, Phenotype, and Function in Human Pulmonary Arterial Hypertension
Samar Farha et al.
Pulmonary Circulation (2012)
Traction Forces of Neutrophils Migrating on Compliant Substrates
Risat A. Jannat et al.
BIOPHYSICAL JOURNAL (2011)
Mechanisms of disease: pulmonary arterial hypertension
Ralph T. Schermuly et al.
NATURE REVIEWS CARDIOLOGY (2011)
Type I interferon (IFN-alpha/beta) rescues B-lymphocytes from apoptosis via PI3K delta/Akt, Rho-A, NF kappa B and Bcl-2/Bcl(XL)
Gamal Badr et al.
CELLULAR IMMUNOLOGY (2010)
Therapeutic efficacy of azaindole-1 in experimental pulmonary hypertension
B. K. Dahal et al.
EUROPEAN RESPIRATORY JOURNAL (2010)
Fasudil reduces monocrotaline-induced pulmonary arterial hypertension: comparison with bosentan and sildenafil
K. T. B. Mouchaers et al.
EUROPEAN RESPIRATORY JOURNAL (2010)
Microtubules Regulate Migratory Polarity through Rho/ROCK Signaling in T Cells
Aya Takesono et al.
PLOS ONE (2010)
KMUP-1 inhibits pulmonary artery proliferation by targeting serotonin receptors/transporter and NO synthase, inactivating RhoA and suppressing AKT/ERK phosphorylation
Hui-Hsuan Chung et al.
VASCULAR PHARMACOLOGY (2010)
RhoA and Rho Kinase Activation in Human Pulmonary Hypertension Role of 5-HT Signaling
Christophe Guilluy et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2009)
Mechanisms of U46619-induced contraction of rat pulmonary arteries in the presence and absence of the endothelium
C. McKenzie et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
Evidence for Rho-Kinase Activation in Patients With Pulmonary Arterial Hypertension
Zhulanqiqige Do E et al.
CIRCULATION JOURNAL (2009)
Analysis of Pulmonary Vasodilator Responses to SB-772077-B [4-(7-((3-Amino-1-pyrrolidinyl)carbonyl)-1-ethyl-1H-imidazo(4,5-c)pyridin-2-yl)-1,2,5-oxadiazol-3-amine], a Novel Aminofurazan-Based Rho Kinase Inhibitor
Jasdeep S. Dhaliwal et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)
In Vivo Imaging and Quantitative Analysis of Leukocyte Directional Migration and Polarization in Inflamed Tissue
Alexander Georg Khandoga et al.
PLOS ONE (2009)
Novel Rho kinase inhibitors with anti-inflammatory and vasodilatory activities
Chris Doe et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
ROCK controls matrix synthesis in vascular smooth muscle cells - Coupling vasoconstriction to vascular remodeling
Rene Chapados et al.
CIRCULATION RESEARCH (2006)
Cross talk between endothelial and smooth muscle cells in pulmonary hypertension - Critical role for serotonin-induced smooth muscle hyperplasia
S Eddahibi et al.
CIRCULATION (2006)
Lysophosphatidic acid induces histamine release from mast cells and skin fragments
T Hashimoto et al.
PHARMACOLOGY (2005)
Physiology and pathophysiology of proteinase-activated receptors (PARs): Role of tryptase/PAR-2 in vascular endothelial barrier function
Y Itoh et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2005)
Cellular and molecular pathobiology of pulmonary arterial hypertension
M Humbert et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2004)
Rho-associated protein kinase contributes to early atherosclerotic lesion formation in mice
Z Mallat et al.
CIRCULATION RESEARCH (2003)
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