相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。The novel driver gene ASAP2 is a potential druggable target in pancreatic cancer
Atsushi Fujii et al.
CANCER SCIENCE (2021)
Antihelminthic Niclosamide Induces Autophagy and Delayed Apoptosis in Human Non-small Lung Cancer Cells In Vitro and In Vivo
Woei-Horng Chai et al.
ANTICANCER RESEARCH (2020)
A comprehensive analysis of clinical trials in pancreatic cancer: what is coming down the pike?
Erryk S. Katayama et al.
Oncotarget (2020)
Overcoming cancer therapeutic bottleneck by drug repurposing
Zhe Zhang et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)
New insights into niclosamide action: autophagy activation in colorectal cancer
Phillip T. Newton
BIOCHEMICAL JOURNAL (2019)
Role of Protein Kinases in Hedgehog Pathway Control and Implications for Cancer Therapy
Valentina Montagnani et al.
CANCERS (2019)
Gli Proteins: Regulation in Development and Cancer
Pawel Niewiadomski et al.
CELLS (2019)
Drug repurposing: a promising tool to accelerate the drug discovery process
Vineela Parvathaneni et al.
DRUG DISCOVERY TODAY (2019)
Non-canonical Hedgehog Signaling Pathway in Cancer: Activation of GLI Transcription Factors Beyond Smoothened
Silvia Pietrobono et al.
FRONTIERS IN GENETICS (2019)
The Emerging Roles of mTORC1 in Macromanaging Autophagy
Akpedje S. Dossou et al.
CANCERS (2019)
Niclosamide-induced Wnt signaling inhibition in colorectal cancer is mediated by autophagy
Jiangbo Wang et al.
BIOCHEMICAL JOURNAL (2019)
Systemic treatment of pancreatic cancer revisited
Michel Ducreux et al.
SEMINARS IN ONCOLOGY (2019)
RAC1B: A Guardian of the Epithelial Phenotype and Protector Against Epithelial-Mesenchymal Transition
Rabea Zinn et al.
CELLS (2019)
Glycogen Synthase Kinase-3 Inhibition Sensitizes Pancreatic Cancer Cells to Chemotherapy by Abrogating the TopBP1/ATR-Mediated DNA Damage Response
Li Ding et al.
CLINICAL CANCER RESEARCH (2019)
Epidemiology of Pancreatic Cancer: Global Trends, Etiology and Risk Factors
Prashanth Rawla et al.
WORLD JOURNAL OF ONCOLOGY (2019)
Phase II trial to investigate the safety and efficacy of orally applied niclosamide in patients with metachronous or sychronous metastases of a colorectal cancer progressing after therapy: the NIKOLO trial
Susen Burock et al.
BMC CANCER (2018)
Challenges in diagnosis of pancreatic cancer
Lulu Zhang et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2018)
Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and nonautonomous Mechanisms
Annan Yang et al.
CANCER DISCOVERY (2018)
Sonic hedgehog protects endometrial hyperplasial cells against oxidative stress via suppressing mitochondrial fission protein dynamin-like GTPase (Drp1)
Jyoti B. Kaushal et al.
FREE RADICAL BIOLOGY AND MEDICINE (2018)
The Autophagy Inhibitor Spautin-1 Antagonizes Rescue of Mutant CFTR Through an Autophagy-Independent and USP13-Mediated Mechanism
Emanuela Pesce et al.
FRONTIERS IN PHARMACOLOGY (2018)
Niclosamide Inhibits Cell Growth and Enhances Drug Sensitivity of Hepatocellular Carcinoma Cells via STAT3 Signaling Pathway
Chengzhi Wang et al.
JOURNAL OF CANCER (2018)
Niclosamide inhibition of STAT3 synergizes with erlotinib in human colon cancer
Lingyi Shi et al.
ONCOTARGETS AND THERAPY (2017)
The regulation of Hh/Gli1 signaling cascade involves Gsk3β- mediated mechanism in estrogen-derived endometrial hyperplasia
Jyoti Bala Kaushal et al.
SCIENTIFIC REPORTS (2017)
Niclosamide: Beyond an antihelminthic drug
Wei Chen et al.
CELLULAR SIGNALLING (2017)
Diagnosis and Detection of Pancreatic Cancer
Linda C. Chu et al.
CANCER JOURNAL (2017)
mTOR Signaling in Growth, Metabolism, and Disease
Robert A. Saxton et al.
CELL (2017)
Anthelminthic drug niclosamide sensitizes the responsiveness of cervical cancer cells to paclitaxel via oxidative stress-mediated mTOR inhibition
Liping Chen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
SQSTM1/p62-mediated autophagy compensates for loss of proteasome polyubiquitin recruiting capacity
Alik Demishtein et al.
AUTOPHAGY (2017)
Effects of mutations in Wnt/β-catenin, hedgehog, Notch and PI3K pathways on GSK-3 activity-Diverse effects on cell growth, metabolism and cancer
James A. McCubrey et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2016)
Identification of Niclosamide as a Novel Anticancer Agent for Adrenocortical Carcinoma
Kei Satoh et al.
CLINICAL CANCER RESEARCH (2016)
Niclosamide inhibits colon cancer progression through downregulation of the Notch pathway and upregulation of the tumor suppressor miR-200 family
Mohammed A. Suliman et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2016)
Niclosamide suppresses renal cell carcinoma by inhibiting Wnt/β-catenin and inducing mitochondrial dysfunctions
Juan Zhao et al.
SPRINGERPLUS (2016)
GSK3β and Gli3 play a role in activation of Hedgehog-Gli pathway in human colon cancer - Targeting GSK3β downregulates the signaling pathway and reduces cell proliferation
Diana Trnski et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2015)
Glycogen Synthase Kinase-3 (GSK3) Inhibition Induces Prosurvival Autophagic Signals in Human Pancreatic Cancer Cells
Benoit Marchand et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States
Lola Rahib et al.
CANCER RESEARCH (2014)
Inhibition of Wnt/β-catenin pathway by niclosamide: A therapeutic target for ovarian cancer
Rebecca C. Arend et al.
GYNECOLOGIC ONCOLOGY (2014)
Effect of Niclosamide on Basal-like Breast Cancers
Angelina I. Londono-Joshi et al.
MOLECULAR CANCER THERAPEUTICS (2014)
Sonic hedgehog signalling pathway: a complex network
Zia Choudhry et al.
ANNALS OF NEUROSCIENCES (2014)
Why should autophagic flux be assessed?
Xiao-jie Zhang et al.
ACTA PHARMACOLOGICA SINICA (2013)
Regulation of the Intrinsic Apoptosis Pathway by Reactive Oxygen Species
Chu-Chiao Wu et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Anticancer Effects of Niclosamide in Human Glioblastoma
Anja Wieland et al.
CLINICAL CANCER RESEARCH (2013)
Noncanonical Regulation of the Hedgehog Mediator GLI1 by c-MYC in Burkitt Lymphoma
Joon Won Yoon et al.
MOLECULAR CANCER RESEARCH (2013)
Treatment of pancreatic cancer in a nude mouse model using high-intensity focused ultrasound
Lixin Jiang et al.
EXPERIMENTAL AND THERAPEUTIC MEDICINE (2013)
Structure-Activity Analysis of Niclosamide Reveals Potential Role for Cytoplasmic pH in Control of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling
Bruno D. Fonseca et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Niclosamide induces mitochondria fragmentation and promotes both apoptotic and autophagic cell death
So Jung Park et al.
BMB REPORTS (2011)
Antineoplastic Mechanisms of Niclosamide in Acute Myelogenous Leukemia Stem Cells: Inactivation of the NF-κB Pathway and Generation of Reactive Oxygen Species
Yanli Jin et al.
CANCER RESEARCH (2010)
The Beclin 1-VPS34 complex - at the crossroads of autophagy and beyond
Sarah F. Funderburk et al.
TRENDS IN CELL BIOLOGY (2010)
Characterization of a cancer stem cell-like side population derived from human pancreatic adenocarcinoma cells
Shi-Neng Zhang et al.
TUMORI JOURNAL (2010)
Regulation of Autophagy by Reactive Oxygen Species (ROS): Implications for Cancer Progression and Treatment
Meghan B. Azad et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
p27Kip1 nuclear localization and cyclin-dependent kinase inhibitory activity are regulated by glycogen synthase kinase-3 in human colon cancer cells
Q. Wang et al.
CELL DEATH AND DIFFERENTIATION (2008)
GSK-3β-dependent destabilization of cyclin D1 mediates replicational stress-induced arrest of cell cycle
Atish Mukherji et al.
FEBS LETTERS (2008)
Glycogen synthase kinase 3β phosphorylates p21WAF1/CIP1 for proteasomal degradation after UV irradiation
Ji Young Lee et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
GSK3β positively regulates Hedgehog signaling through Sufu in mammalian cells
Kei Takenaka et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Autophagy and signaling: their role in cell survival and cell death
P Codogno et al.
CELL DEATH AND DIFFERENTIATION (2005)
A comprehensive characterization of pancreatic ductal carcinoma cell lines:: towards the establishment of an in vitro research platform
B Sipos et al.
VIRCHOWS ARCHIV (2003)
Role of LAMP-2 in lysosome biogenesis and autophagy
EL Eskelinen et al.
MOLECULAR BIOLOGY OF THE CELL (2002)