4.7 Article

Frailty Assessment in a Cohort of Elderly Patients with Severe Symptomatic Aortic Stenosis: Insights from the FRailty Evaluation in Severe Aortic Stenosis (FRESAS) Registry

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JOURNAL OF CLINICAL MEDICINE
卷 10, 期 11, 页码 -

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MDPI
DOI: 10.3390/jcm10112345

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transcatheter aortic valve replacement (TAVI); Transcatheter Aortic Valve Implantation (TAVR); frailty; aortic stenosis

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The study aimed to determine the prevalence of frailty in patients undergoing aortic valve replacement, with 19.6% of patients identified as frail, associated with factors such as age, functional index, and atrial fibrillation.
Background: Precise evaluation of the degree of frailty is a fundamental part of the global geriatric assessment that helps to avoid therapies that could be futile. Our main objective was to determine the prevalence of frailty in a specific consult of patients undergoing aortic valve replacement. Methods: From May 2018 to February 2020, all consecutive patients >= 75 years old, with severe symptomatic aortic stenosis, undergoing valve replacement in the Principality of Asturias (Northern Spain) were evaluated. Results: A total of 286 patients were assessed. The mean age was 84 +/- 4.01 years old; 175 (61.2%) were female. The short performance physical battery score was 8.5 +/- 2.4 and the prevalence of frailty was 19.6% (56 patients). In the multivariable analysis, age, Barthel index and atrial fibrillation were independent predictors of frailty. Conclusions: The prevalence of frailty in our sample patients undergoing aortic valve replacement, evaluated by a standardized protocol, was 19.6%.

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