4.7 Article

Evaluation of tumor immune contexture among intrinsic molecular subtypes helps to predict outcome in early breast cancer

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Immune checkpoint inhibitors: Key trials and an emerging role in breast cancer

Nicola Gaynor et al.

Summary: This article reviews the use of immune checkpoint inhibitors as immunomodulatory agents for relieving immune suppression caused by tumors. These inhibitors have shown impressive results in various solid cancers, especially melanoma and non-small cell lung cancer. They have potential benefits for most cancer types and numerous clinical studies are being conducted to explore their efficacy. The article provides an overview of key clinical trials involving immune checkpoint inhibitors targeting PD-1, PD-L1, and CTLA-4, and discusses emerging therapies targeting these checkpoints as well as the status of immune checkpoint inhibitors in breast cancer.

SEMINARS IN CANCER BIOLOGY (2022)

Article Medicine, Research & Experimental

Spatially distinct tumor immune microenvironments stratify triple-negative breast cancers

Tina Gruosso et al.

JOURNAL OF CLINICAL INVESTIGATION (2019)

Editorial Material Oncology

Analyzing the Immunological Landscape of a Tumor-Heterogeneity of Immune Infiltrates in Breast Cancer as a New Prognostic Indicator

Carsten Denkert et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2018)

Editorial Material Oncology

Analyzing the Immunological Landscape of a Tumor-Heterogeneity of Immune Infiltrates in Breast Cancer as a New Prognostic Indicator

Carsten Denkert et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2018)

Article Immunology

The Immune Landscape of Cancer

Vesteinn Thorsson et al.

IMMUNITY (2018)

Article Multidisciplinary Sciences

Human breast tumor-infiltrating CD8+ T cells retain polyfunctionality despite PD-1 expression

Colt A. Egelston et al.

NATURE COMMUNICATIONS (2018)

Review Oncology

Breast Cancer Immunotherapy: Facts and Hopes

Leisha A. Emens

CLINICAL CANCER RESEARCH (2018)

Review Oncology

Relevance of Tumor-Infiltrating Immune Cell Composition and Functionality for Disease Outcome in Breast Cancer

Rico D. Bense et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2017)

Review Oncology

Relevance of Tumor-Infiltrating Immune Cell Composition and Functionality for Disease Outcome in Breast Cancer

Rico D. Bense et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2017)

Review Biochemistry & Molecular Biology

T memory stem cells in health and disease

Luca Gattinoni et al.

NATURE MEDICINE (2017)

Review Oncology

The immune contexture in cancer prognosis and treatment

Wolf H. Fridman et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2017)

Article Multidisciplinary Sciences

Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer

Julienne L. Carstens et al.

NATURE COMMUNICATIONS (2017)

Article Biochemical Research Methods

Genefu: an R/Bioconductor package for computation of gene expression-based signatures in breast cancer

Deena M. A. Gendoo et al.

BIOINFORMATICS (2016)

Review Oncology

Clinical relevance of host immunity in breast cancer: from TILs to the clinic

Peter Savas et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2016)

Review Oncology

Prognostic and predictive value of tumor in early breast cancer

Carmen Criscitiello et al.

CANCER TREATMENT REVIEWS (2016)

Article Biochemistry & Molecular Biology

The prognostic landscape of genes and infiltrating immune cells across human cancers

Andrew J. Gentles et al.

NATURE MEDICINE (2015)

Article Biochemical Research Methods

Robust enumeration of cell subsets from tissue expression profiles

Aaron M. Newman et al.

NATURE METHODS (2015)

Article Oncology

PAM50 proliferation score as a predictor of weekly paclitaxel benefit in breast cancer

Miguel Martin et al.

BREAST CANCER RESEARCH AND TREATMENT (2013)

Article Oncology

Gene Modules and Response to Neoadjuvant Chemotherapy in Breast Cancer Subtypes: A Pooled Analysis

Michail Ignatiadis et al.

JOURNAL OF CLINICAL ONCOLOGY (2012)

Article Pathology

Tumour-infiltrating macrophages and clinical outcome in breast cancer

S. M. A. Mahmoud et al.

JOURNAL OF CLINICAL PATHOLOGY (2012)

Article Biochemistry & Molecular Biology

A refined molecular taxonomy of breast cancer

M. Guedj et al.

ONCOGENE (2012)

Article Multidisciplinary Sciences

Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling

Vessela N. Kristensen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Oncology

The immune contexture in human tumours: impact on clinical outcome

Wolf Herman Fridman et al.

NATURE REVIEWS CANCER (2012)

Article Oncology

Tumor-Infiltrating CD8+ Lymphocytes Predict Clinical Outcome in Breast Cancer

Sahar M. A. Mahmoud et al.

JOURNAL OF CLINICAL ONCOLOGY (2011)

Article Oncology

Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes

Joel S. Parker et al.

JOURNAL OF CLINICAL ONCOLOGY (2009)

Article Medicine, General & Internal

Effector memory T cells, early metastasis, and survival in colorectal cancer

F Pagès et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)

Article Medicine, General & Internal

A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer

S Paik et al.

NEW ENGLAND JOURNAL OF MEDICINE (2004)

Article Behavioral Sciences

Controlling the false discovery rate in behavior genetics research

Y Benjamini et al.

BEHAVIOURAL BRAIN RESEARCH (2001)

Article Multidisciplinary Sciences

Molecular portraits of human breast tumours

CM Perou et al.

NATURE (2000)