4.8 Article

Fast cortical dynamics encode tactile grating orientation during active touch

期刊

SCIENCE ADVANCES
卷 7, 期 36, 页码 -

出版社

AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/sciadv.abf7096

关键词

-

资金

  1. Paris-Saclay University (Lidex NeuroSaclay)
  2. International Human Frontier Science Program Organization [CDA-0064-2015]
  3. Fondation pour l'Audition [FPA IDA02]
  4. Fondation pour la Recherche Medicale [ECO20170637482]
  5. Fondation pour l'Audition

向作者/读者索取更多资源

This study shows that mice can use their whiskers to discriminate object orientation, and that fast cortical dynamics extract orientation information more closely resembling concurrent psychophysical measurements than single neuron orientation tuning curves, conveying both stimulus and choice-related information.
Touch-based object recognition relies on perception of compositional tactile features like roughness, shape, and surface orientation. However, besides roughness, it remains unclear how these different tactile features are encoded by neural activity that is linked with perception. Here, we establish a cortex-dependent perceptual task in which mice discriminate tactile gratings on the basis of orientation using only their whiskers. Multielectrode recordings in the barrel cortex reveal weak orientation tuning in average firing rates (500-ms time scale) during grating exploration despite high levels of cortical activity. Just before decision, orientation information extracted from fast cortical dynamics (100-ms time scale) more closely resembles concurrent psychophysical measurements than single neuron orientation tuning curves. This temporal code conveys both stimulus and choice/action-related information, suggesting that fast cortical dynamics during exploration of a tactile object both reflect the physical stimulus and affect the decision.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.8
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据