Palladium-Catalyzed Aryl-Carbamoylation of Alkene-Tethered Carbamoyl Chlorides: Access to Diverse Aryl-Functionalized Oxindoles

Utilizing a palladium-catalyzed cascade strategy, we have developed an intermolecular aryl-carbamoylation of unactivated alkenes under mild conditions, allowing for facile access to diverse aryl-functionalized oxindoles from alkene-tethered carbamoyl chlorides in moderate to good yields.

Automated summary

By utilizing a palladium-catalyzed cascade strategy, an intermolecular aryl-carbamoylation of unactivated alkenes was developed under mild conditions, providing access to diverse aryl-functionalized oxindoles in moderate to good yields.