期刊
JOURNAL OF ONCOLOGY PHARMACY PRACTICE
卷 27, 期 8, 页码 1958-1962出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/10781552211034473
关键词
Antineoplastic agents; cytotoxic drugs; chemotherapy; safe handling
Safe handling precautions are important to prevent occupational exposure to hazardous antineoplastic drugs. By establishing a list of antineoplastic drugs with cytotoxic or non-cytotoxic designations based on mechanistic criteria, this review provides a reference for developing safe handling policies.
Safe handling precautions are an important measure used to prevent occupational exposure to hazardous antineoplastic drugs. Historically, the terms 'antineoplastic', 'chemotherapy' and 'cytotoxic' are frequently conflated. However, many current antineoplastic drugs do not have cytotoxic mechanisms of actions, leading to confusion when developing safe handling policies. Based on the mechanistic criteria outlined in this review, we have compiled a list of the most commonly used antineoplastic drugs with their cytotoxic or non-cytotoxic designations. We propose that this list can be used when discussing drug-specific safe handling precaution measures.
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