期刊
COATINGS
卷 11, 期 7, 页码 -出版社
MDPI
DOI: 10.3390/coatings11070811
关键词
substituted hydroxyapatite; bioactive glass; bioactive glass-ceramic; PLD
The deposition of thin films is a common method to improve bone bonding ability of implants, with nanosecond Pulsed Laser Deposition (PLD) offering significant advantages. Studies focus on experimental conditions, deposition of bioactive materials, and the performance of coatings towards biomedical applications. There is potential for further research and development in this area.
The deposition of thin films of bioactive materials is the most common approach to improve the bone bonding ability of an implant surface. With this purpose, several wet and plasma assisted deposition methods were proposed in the scientific literature. In this review, we considered films obtained by nanosecond Pulsed Laser Deposition (PLD). Since hydroxyapatite (HA) has composition and structure similar to that of the mineral component of the bone, the initial studies focused on the selection of experimental conditions that would allow the deposition of films that retain HA stoichiometry and crystallinity. However, biological apatite was found to be a poorly crystalline and multi-substituted mineral; consequently, the attention of researchers was oriented towards the deposition of substituted HA, glass (BG), and glass-ceramic (BGC) bioactive materials to exploit the biological relevance of foreign ions and crystallinity. In this work, after a description of the nanosecond ablation and film growth of ceramic materials, we reported studies on the mechanism of HA ablation and deposition, evidencing the peculiarities of PLD. The literature concerning the PLD of ion substituted HA, BG, and BGC was then reviewed and the performances of the coatings were discussed. We concluded by describing the advantages, limitations, and perspectives of PLD for biomedical applications.
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