Triclosan-containing sutures: safety and resistance issues need to be addressed prior to generalized use

Triclosan (TCS), a synthetic antimicrobial, has been incorporated into a variety of personal care products worldwide. Since 2016, upon the recommendation of World Health Organization (WHO), the use of TCS-containing sutures (TCSCS) to prevent surgical site infections (SSI) has become a common practice. However, TCS is a subject of environmental and public health concern and has been ranked as a chemical of serious concern to be avoided based on GreenScreen(R) hazard assessment. Recent reports on the efficacy of TCSCS to prevent SSI have revealed conflicting results. Here, we aim to highlight and discuss various safety and antimicrobial resistance concerns associated with the generalized use of TCSCS. Further, we emphasize that the long-term health benefits must be evaluated before the incorporation of TCS into surgical sutures.

Automated summary

This review discusses the safety and antimicrobial resistance concerns associated with the use of TCS-containing sutures, emphasizing the importance of evaluating long-term health benefits before incorporation.