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Lifelong Bilingualism Functions as an Alternative Intervention for Cognitive Reserve Against Alzheimer's Disease

期刊

FRONTIERS IN PSYCHIATRY
卷 12, 期 -, 页码 -

出版社

FRONTIERS MEDIA SA
DOI: 10.3389/fpsyt.2021.696015

关键词

bilingualism; cognitive decline; cognitive reserve; dementia; Alzheimer's disease

资金

  1. National Natural Science Foundation of China [82060407]
  2. Scientific Research Fund of Jiangxi Provincial Education Department [GJJ190812]
  3. General Project from Gannan Medical University [YB201966]

向作者/读者索取更多资源

Bilingualism significantly delays the onset of dementia and protects against cognitive decline, acting as a pharmacological intervention with no side effects. However, further research is needed to investigate the pharmacological parameters of bilingualism.
Bilingualism has been reported to significantly delay the onset of dementia and plays an important role in the management of Alzheimer's disease (AD), a condition inducing impairment in the brain network and cognitive decline. Cognitive reserve is associated with the adaptive maintenance of neural functions by protecting against neuropathology. Bilingualism acts as a beneficial environmental factor contributing to cognitive reserve, although some potential confounding variables still need further elucidation. In this article, the relationship between bilingualism and cognitive reserve is discussed, interpreting the advantage of bilingualism in protecting against cognitive decline. In addition, the possible brain and biochemical mechanisms, supporting the advantageous effects of bilingualism in delaying the onset of dementia, involved in bilingualism are reviewed. Effectively, bilingualism can be considered as a pharmacological intervention with no side effects. However, the investigation of the pharmacological parameters of bilingualism is still at an early stage.

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