4.7 Article

Estimation of Pubertal Growth Spurt Parameters in Children and Adolescents Living at Moderate Altitude in Colombia

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FRONTIERS IN ENDOCRINOLOGY
卷 12, 期 -, 页码 -

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FRONTIERS MEDIA SA
DOI: 10.3389/fendo.2021.718292

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growth velocity; stature; final height; Preece-Baines function; children

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Through a cross-sectional study in schoolchildren from Bogota, Colombia, it was found that boys reached a final height of 170.8 cm and girls at 157.9 cm; boys reached peak height velocity at 12.71 years, while girls at 10.4 years, 2.2 years earlier than boys. Boys had a higher growth speed in height (7.4 cm/y) compared to girls (7.0 cm/y).
Objective Knowledge of the biological parameters of pubertal growth spurt allows verification of secular changes and exploration of the timing of puberty. The aim of the study was to estimate final height, age at peak height velocity (APHV), and peak height velocity PHV (cm/y) in children and adolescents living at moderate altitude in Colombia. Methods A cross-sectional study was designed in 2.295 schoolchildren from Bogota (Colombia) with an age range from 5.0 to 18.9 years. Height (cm) was assessed. Preece-Baines model 1 (1PB) was used to make inferences about mathematical and biological parameters. Results The five mathematical parameters estimated in general have reflected quality in the fit to the model, reflecting a small residual error. Final height was reached in boys at 170.8 +/- 0.4 cm and in girls at 157.9 +/- 0.2 cm. APHV was estimated at 12.71 +/- 0.1 years in boys and 10.4 +/- 0.2 years in girls. Girls reached APHV 2.2 years earlier than boys. In relation to PHV (cm/y), boys reached higher growth speed in height (7.4 +/- 0.4 cm/y), and in girls it was (7.0 +/- 0.2 cm/y). Conclusion It was determined that final height was reached at 170.8 +/- 0.4 cm in boys and 157.9 +/- 0.2 cm in girls, and APHV (years) and PHV (cm/ye) were reached relatively early and with average peak velocity similar to Asian and Western populations. A large-scale longitudinal study is needed to confirm these findings.

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