期刊
FRONTIERS IN CHEMISTRY
卷 9, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fchem.2021.699284
关键词
localized surface plasmon resonance; hollow gold nanostructures; biomedical application; biosensors; bioimaging; photothermal therapy
资金
- National Research Foundation of Korea (NRF) - Korean government (MSIT) [2019R1A4A1024116, 2019R1F1A1062216, 2018R1D1A3B07049650]
- National Research Foundation of Korea [2019R1F1A1062216, 2019R1A4A1024116, 2018R1D1A3B07049650] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Hollow gold nanostructures have significant advantages such as absorbing near-infrared light, anti-corrosiveness, and large surface area, making them suitable for biomedical applications. They can be used for drug delivery, biosensing, bioimaging, and photothermal therapy.
The localized surface plasmon resonance of metallic nanoparticles has attracted much attention owing to its unique characteristics, including the enhancement of signals in sensors and photothermal effects. In particular, hollow gold nanostructures are highly promising for practical applications, with significant advantages being found in their material properties and structures: 1) the interaction between the outer surface plasmon mode and inner cavity mode leads to a greater resonance, allowing it to absorb near-infrared light, which can readily penetrate tissue; 2) it has anti-corrosiveness and good biocompatibility, which makes it suitable for biomedical applications; 3) it shows a reduced net density and large surface area, allowing the possibility of nanocarriers for drug delivery. In this review, we present information on the classification, characteristics, and synthetic methods of hollow gold nanostructures; discuss the recent advances in hollow gold nanostructures in biomedical applications, including biosensing, bioimaging, photothermal therapy, and drug delivery; and report on the existing challenges and prospects for hollow gold nanostructures.
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