相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。2020 Alzheimer's disease facts and figures
[Anonymous]
ALZHEIMERS & DEMENTIA (2020)
The Amazon rain forest plant Uncaria tomentosa (cat's claw) and its specific proanthocyanidin constituents are potent inhibitors and reducers of both brain plaques and tangles
Alan D. Snow et al.
SCIENTIFIC REPORTS (2019)
Molecular Pathogenesis of the Tauopathies
Jurgen Gotz et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 14 (2019)
Procyanidins and Alzheimer's Disease
Siqi Zhao et al.
MOLECULAR NEUROBIOLOGY (2019)
Reconsideration of Amyloid Hypothesis and Tau Hypothesis in Alzheimer's Disease
Fuyuki Kametani et al.
FRONTIERS IN NEUROSCIENCE (2018)
Influence of EGCG on α-synuclein (αS) aggregation and identification of their possible binding mode: A computational study using molecular dynamics simulation
Xuewei Liu et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2018)
Protective V127 prion variant prevents prion disease by interrupting the formation of dimer and fibril from molecular dynamics simulations
Shuangyan Zhou et al.
SCIENTIFIC REPORTS (2016)
Tau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective Strategies
Goran Simic et al.
BIOMOLECULES (2016)
Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies
Marcus Pickhardt et al.
CURRENT ALZHEIMER RESEARCH (2015)
Tau stabilizes microtubules by binding at the interface between tubulin heterodimers
Harindranath Kadavath et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
The green tea polyphenol (-)-epigallocatechin gallate prevents the aggregation of tau protein into toxic oligomers at substoichiometric ratios
Heike J. Wobst et al.
FEBS LETTERS (2015)
Emerging Therapeutics for Alzheimer's Disease
Karen Chiang et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 54 (2014)
Identification of structural determinants on tau protein essential for its pathological function: novel therapeutic target for tau immunotherapy in Alzheimer's disease
Eva Kontsekova et al.
ALZHEIMERS RESEARCH & THERAPY (2014)
Amyloid-β and Tau The Trigger and Bullet in Alzheimer Disease Pathogenesis
George S. Bloom
JAMA NEUROLOGY (2014)
Tau-Derived-Hexapeptide 306VQIVYK311 Aggregation Inhibitors: Nitrocatechol Moiety as A Pharmacophore In Drug Design
Tarek Mohamed et al.
ACS CHEMICAL NEUROSCIENCE (2013)
Driving Forces and Structural Determinants of Steric Zipper Peptide Oligomer Formation Elucidated by Atomistic Simulations
Dirk Matthes et al.
JOURNAL OF MOLECULAR BIOLOGY (2012)
Assessing the Performance of the MM/PBSA and MM/GBSA Methods. 1. The Accuracy of Binding Free Energy Calculations Based on Molecular Dynamics Simulations
Tingjun Hou et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2011)
Towards a Pharmacophore for Amyloid
Meytal Landau et al.
PLOS BIOLOGY (2011)
The Importance of Hydrogen Bonding between the Glutamine Side Chains to the Formation of Amyloid VQIVYK Parallel β-Sheets: An ONIOM DFT/AM1 Study
Joshua A. Plumley et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Inhibition of tau fibrillization by oleocanthal via reaction with the amino groups of tau
Wenkai Li et al.
JOURNAL OF NEUROCHEMISTRY (2009)
High throughput screening for small molecule inhibitors of heparin-induced tau fibril formation
Alex Crowe et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Untangling tau hyperphosphorylation in drug design for neurodegenerative diseases
Michael P. Mazanetz et al.
NATURE REVIEWS DRUG DISCOVERY (2007)
Atomic structures of amyloid cross-β spines reveal varied steric zippers
Michael R. Sawaya et al.
NATURE (2007)
A Phase II study targeting amyloid-β with 3APS in mild-to-moderate Alzheimer disease
P. S. Aisen et al.
NEUROLOGY (2006)
Comparison of multiple amber force fields and development of improved protein backbone parameters
Viktor Hornak et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2006)
A century of Alzheimer's disease
Michel Goedert et al.
SCIENCE (2006)
Structural stability and dynamics of an amyloid-forming peptide GNNQQNY from the yeast prion sup-35
Jie Zheng et al.
BIOPHYSICAL JOURNAL (2006)
Prediction of nucleating sequences from amyloidogenic propensities of tau-related peptides
FAR Quijano et al.
BIOCHEMISTRY (2006)
Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins
S Taniguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
MMTSB Tool Set: enhanced sampling and multiscale modeling methods for applications in structural biology
M Feig et al.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2004)
Development and testing of a general amber force field
JM Wang et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
The formation of straight and twisted filaments from short tau peptides
WJ Goux et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Hyperphosphorylation induces self-assembly of τ into tangles of paired helical filaments/straight filaments
AD Alonso et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Assembly of τ protein into Alzheimer paired helical filaments depends on a local sequence motif (306VQIVYK311) forming β structure
M von Bergen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
分享论文
