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Updates in Diabetic Wound Healing, Inflammation, and Scarring

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SEMINARS IN PLASTIC SURGERY
卷 35, 期 3, 页码 153-158

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THIEME MEDICAL PUBL INC
DOI: 10.1055/s-0041-1731460

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diabetes; wound healing; inflammation; scarring

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Diabetic patients are prone to wound complications, with changes such as excessive inflammation and reduced angiogenesis affecting the healing process. Factors like nutritional status and glycemic control play a significant role in diabetic wound outcomes. Various treatments are available to address diabetic wounds.
Diabetic patients can sustain wounds either as a sequelae of their disease process or postoperatively. Wound healing is a complex process that proceeds through phases of inflammation, proliferation, and remodeling. Diabetes results in several pathological changes that impair almost all of these healing processes. Diabetic wounds are often characterized by excessive inflammation and reduced angiogenesis. Due to these changes, diabetic patients are at a higher risk for postoperative wound healing complications. There is significant evidence in the literature that diabetic patients are at a higher risk for increased wound infections, wound dehiscence, and pathological scarring. Factors such as nutritional status and glycemic control also significantly influence diabetic wound outcomes. There are a variety of treatments available for addressing diabetic wounds.

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