期刊
RESULTS IN PHYSICS
卷 27, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.rinp.2021.104448
关键词
HIV/HTLV co-infection; HIV-specific antibody immune response; Global stability
资金
- Taif University, Taif, Saudi Arabia [TURSP-2020/70]
This paper presents two HIV/HTLV co-infection models with antibody immune response, investigating the properties and global stability of the solutions. The stability results are based on constructing Lyapunov functions and using LaSalle's invariance principle. Numerical simulations are conducted to support the theoretical findings.
This paper presents two HIV/HTLV co-infection models with antibody immune response. The first model is given by 5-dimensional ODEs that describe the within-host interactions of five compartments, susceptible CD4(+) T cells, HIV-infected cells, HTLV-infected cells, free HIV particles and HIV-specific antibodies. In the second model, we incorporate both silent HIV-infected cells and silent HTLV-infected cells. For both models we address the properties of the solutions, then we investigate the global stability of the steady states. Our global stability results are based on constructing Lyapunov functions and using LaSalle's invariance principle. To support our theoretical results we conduct some numerical simulations.
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