期刊
PHOTONICS RESEARCH
卷 9, 期 10, 页码 1970-1978出版社
CHINESE LASER PRESS
DOI: 10.1364/PRJ.433335
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- Ministry of Science and Technology, Taiwan [MOST 110-2112-M-029-005]
A simple method is proposed to increase the refractive index sensitivities of terahertz metamaterials, enabling them to detect low-concentration proteins and potentially dangerous viruses. The floating terahertz metamaterial provides an extremely large refractive index sensitivity of 532 GHz/RIU and is a significant achievement in the development of protein sensors.
In the diagnosis of severe contagious diseases such as Ebola, severe acute respiratory syndrome, and COVID-19, there is an urgent need for protein sensors with large refractive index sensitivities. Current terahertz metamaterials cannot be used to develop such protein sensors due to their low refractive index sensitivities. A simple method is proposed that is compatible with all geometrical structures of terahertz metamaterials to increase their refractive index sensitivities. This method uses patterned photoresist to float the split-ring resonators (SRRs) of a terahertz metamaterial at a height of 30 mu m from its substrate that is deposited with complementary SRRs. The floating terahertz metamaterial has an extremely large refractive index sensitivity of 532 GHz/RIU because its near field is not distributed over the substrate and also because the complementary SRRs confine the field above the substrate. The floating terahertz metamaterial senses bovine serum albumin (BSA) and the protein binding of BSA and anti-BSA as BSA, and anti-BSA solutions with low concentrations that are smaller than 0.150 mu mol/L are sequentially dropped onto it. The floating terahertz metamaterial is a great achievement to develop protein sensors with extremely large refractive index sensitivities, and has the potential to sense dangerous viruses. (C) 2021 Chinese Laser Press
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