相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Effect of Subcutaneous Semaglutide vs Placebo as an Adjunct to Intensive Behavioral Therapy on Body Weight in Adults With Overweight or Obesity The STEP 3 Randomized Clinical Trial
Thomas A. Wadden et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)
Pharmacological Targeting of Endoplasmic Reticulum Stress in Pancreatic Beta Cells
Sara Bilekova et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2021)
CD81 marks immature and dedifferentiated pancreatic β-cells
Ciro Salinno et al.
MOLECULAR METABOLISM (2021)
Claudin 4 in pancreatic β cells is involved in regulating the functional state of adult islets
Hongtu Li et al.
FEBS OPEN BIO (2020)
Wolfram syndrome 1 gene regulates pathways maintaining beta-cell health and survival
Damien Abreu et al.
LABORATORY INVESTIGATION (2020)
Patch-Seq Links Single-Cell Transcriptomes to Human Islet Dysfunction in Diabetes
Joan Camunas-Soler et al.
CELL METABOLISM (2020)
Sel1L-Hrd1 ER-associated degradation maintains β cell identity via TGF-β signaling
Neha Shrestha et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
Genetic deletion of Urocortin 3 does no prevent functional maturation of beta cells
Jessica L. Huang et al.
JOURNAL OF ENDOCRINOLOGY (2020)
Factors associated with complete and partial remission, improvement, or unchanged diabetes status of obese adults 1 year after sleeve gastrectomy
Isra Elgenaied et al.
SURGERY FOR OBESITY AND RELATED DISEASES (2020)
Once-Weekly Semaglutide Reduces HbA1c and Body Weight in Patients with Type 2 Diabetes Regardless of Background Common OAD: a Subgroup Analysis from SUSTAIN 2-4 and 10
Matthew Capehorn et al.
DIABETES THERAPY (2020)
Characterization of Signaling Pathways Associated with Pancreatic β-cell Adaptive Flexibility in Compensation of Obesity-linked Diabetes in db/db Mice
Taewook Kang et al.
MOLECULAR & CELLULAR PROTEOMICS (2020)
Characterizing pancreatic (3-cell heterogeneity in the streptozotocin model by single -cell transcriptomic analysis Check
Ye Feng et al.
MOLECULAR METABOLISM (2020)
Caloric restriction recovers impaired beta-cell-beta-cell gap junction coupling, calcium oscillation coordination, and insulin secretion in prediabetic mice
Maria Esmeria Corezola da Amaral et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2020)
Generalizing RNA velocity to transient cell states through dynamical modeling
Volker Bergen et al.
NATURE BIOTECHNOLOGY (2020)
Glucose-Lipid Metabolism in Obesity with Elevated Prolactin Levels and Alteration of Prolactin Levels After Laparoscopic Sleeve Gastrectomy
Xingchun Wang et al.
OBESITY SURGERY (2020)
Predictive Model of Type 2 Diabetes Remission after Metabolic Surgery in Chinese Patients
Yufang Luo et al.
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (2020)
Targeted pharmacological therapy restores β-cell function for diabetes remission
Stephan Sachs et al.
NATURE METABOLISM (2020)
Insulin resistance and insulin hypersecretion in the metabolic syndrome and type 2 diabetes: Time for a conceptual framework shift
Christopher J. Nolan et al.
DIABETES & VASCULAR DISEASE RESEARCH (2019)
Single-Cell Heterogeneity Analysis and CRISPR Screen Identify Key β-Cell-Specific Disease Genes
Zhou Fang et al.
CELL REPORTS (2019)
Scrublet: Computational Identification of Cell Doublets in Single-Cell Transcriptomic Data
Samuel L. Wolock et al.
CELL SYSTEMS (2019)
Transcriptional Heterogeneity of Beta Cells in the Intact Pancreas
Lydia Farack et al.
DEVELOPMENTAL CELL (2019)
Endoplasmic Reticulum-Associated Degradation (ERAD) Has a Critical Role in Supporting Glucose-Stimulated Insulin Secretion in Pancreatic -Cells
Yabing Hu et al.
DIABETES (2019)
Dimensionality reduction for visualizing single-cell data using UMAP
Etienne Becht et al.
NATURE BIOTECHNOLOGY (2019)
Bariatric Surgery Worldwide: Baseline Demographic Description and One-Year Outcomes from the Fourth IFSO Global Registry Report 2018
Richard Welbourn et al.
OBESITY SURGERY (2019)
Prolactin Receptor Signaling Regulates a Pregnancy-Specific Transcriptional Program in Mouse Islets
Mark E. Pepin et al.
ENDOCRINOLOGY (2019)
PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells
F. Alexander Wolf et al.
GENOME BIOLOGY (2019)
Sleeve Gastrectomy Improves Glycemia Independent of Weight Loss by Restoring Hepatic Insulin Sensitivity
Samir Abu-Gazala et al.
DIABETES (2018)
Pseudotime Ordering of Single Human -Cells Reveals States of Insulin Production and Unfolded Protein Response
Yurong Xin et al.
DIABETES (2018)
RNA-Seq Analysis of Islets to Characterise the Dedifferentiation in Type 2 Diabetes Model Mice db/db
Abraham Neelankal John et al.
ENDOCRINE PATHOLOGY (2018)
The protein kinase PERK/EIF2AK3 regulates proinsulin processing not via protein synthesis but by controlling endoplasmic reticulum chaperones
Carrie R. Sowers et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
TGR5 contributes to glucoregulatory improvements after vertical sleeve gastrectomy in mice
Anne K. McGavigan et al.
GUT (2017)
Pancreatic β-Cells Express the Fetal Islet Hormone Gastrin in Rodent and Human Diabetes
Tehila Dahan et al.
DIABETES (2017)
Preoperative Beta Cell Function Is Predictive of Diabetes Remission After Bariatric Surgery
Pedro Souteiro et al.
OBESITY SURGERY (2017)
Bariatric Surgery versus Intensive Medical Therapy for Diabetes-5-Year Outcomes
Philip R. Schauer et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
db/db Mice Exhibit Features of Human Type 2 Diabetes That Are Not Present in Weight-Matched C57BL/6J Mice Fed a Western Diet
Susan J. Burke et al.
JOURNAL OF DIABETES RESEARCH (2017)
SOX4 Allows Facultative β-Cell Proliferation Through Repression of Cdkn1a
Eric E. Xu et al.
DIABETES (2017)
Pair Feeding, but Not Insulin, Phloridzin, or Rosiglitazone Treatment, Curtails Markers of β-Cell Dedifferentiation in db/db Mice
Emi Ishida et al.
DIABETES (2017)
Sleeve gastrectomy, but not duodenojejunostomy, preserves total beta-cell mass in Goto-Kakizaki rats evaluated by three-dimensional optical projection tomography
Eivind Grong et al.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES (2016)
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes
Asa Segerstolpe et al.
CELL METABOLISM (2016)
Synaptotagmin-7 Functions to Replenish Insulin Granules for Exocytosis in Human Islet β-Cells
Subhankar Dolai et al.
DIABETES (2016)
Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes: A Joint Statement by International Diabetes Organizations
Francesco Rubino et al.
DIABETES CARE (2016)
β-Cell Deficit in Obese Type 2 Diabetes, a Minor Role of β-Cell Dedifferentiation and Degranulation
Alexandra E. Butler et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2016)
Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes
Francesca Cinti et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2016)
Identification of proliferative and mature β-cells in the islets of Langerhans
Erik Bader et al.
NATURE (2016)
Diffusion pseudotime robustly reconstructs lineage branching
Laleh Haghverdi et al.
NATURE METHODS (2016)
Impact of islet architecture on β-cell heterogeneity, plasticity and function
Sara S. Roscioni et al.
NATURE REVIEWS ENDOCRINOLOGY (2016)
Pharmacology and therapeutic implications of current drugs for type 2 diabetes mellitus
Abd A. Tahrani et al.
NATURE REVIEWS ENDOCRINOLOGY (2016)
Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
Maxim V. Kuleshov et al.
NUCLEIC ACIDS RESEARCH (2016)
Preventative Sleeve Gastrectomy Contributes to Maintaining β Cell Function in db/db Diabetic Mouse
Feng Li et al.
OBESITY SURGERY (2016)
Osteoprotegerin Regulates Pancreatic β-Cell Homeostasis upon Microbial Invasion
Yukiko Kuroda et al.
PLOS ONE (2016)
Aldehyde dehydrogenase 1a3 defines a subset of failing pancreatic β cells in diabetic mice
Ja Young Kim-Muller et al.
NATURE COMMUNICATIONS (2016)
MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes
Elvira Ganic et al.
CELL REPORTS (2016)
Reversibility of β-Cell-Specific Transcript Factors Expression by Long-Term Caloric Restriction in db/db Mouse
Chunjun Sheng et al.
JOURNAL OF DIABETES RESEARCH (2016)
A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure
Maayan Baron et al.
CELL SYSTEMS (2016)
Repurposing an Osteoporosis Drug for β Cell Regeneration in Diabetic Patients
Felizitas Schmitz et al.
CELL METABOLISM (2015)
The Role of Gut Adaptation in the Potent Effects of Multiple Bariatric Surgeries on Obesity and Diabetes
Randy J. Seeley et al.
CELL METABOLISM (2015)
Osteoprotegerin and Denosumab Stimulate Human Beta Cell Proliferation through Inhibition of the Receptor Activator of NF-κB Ligand Pathway
Nagesha Guthalu Kondegowda et al.
CELL METABOLISM (2015)
Insulin demand regulates β cell number via the unfolded protein response
Rohit B. Sharma et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
limma powers differential expression analyses for RNA-sequencing and microarray studies
Matthew E. Ritchie et al.
NUCLEIC ACIDS RESEARCH (2015)
The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells
Justin R. Hassler et al.
PLOS BIOLOGY (2015)
Prolactin Receptors and Placental Lactogen Drive Male Mouse Pancreatic Islets to Pregnancy-Related mRNA Changes
Lotte Goyvaerts et al.
PLOS ONE (2015)
Pancreatic β Cell Dedifferentiation in Diabetes and Redifferentiation following Insulin Therapy
Zhiyu Wang et al.
CELL METABOLISM (2014)
Gastric Bypass Improves b-Cell Function and Increases b-Cell Mass in a Porcine Model
Andreas Lindqvist et al.
DIABETES (2014)
β-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment
Philippe A. Halban et al.
DIABETES CARE (2014)
Bariatric Surgery versus Intensive Medical Therapy for Diabetes REPLY
Philip R. Schauer et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Reduction of pancreatic β-cell dedifferentiation after gastric bypass surgery in diabetic rats
Bangguo Qian et al.
JOURNAL OF MOLECULAR CELL BIOLOGY (2014)
Bariatric Surgery versus Intensive Medical Therapy for Diabetes-3-Year Outcomes
Philip R. Schauer et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Characterisation of Age-Dependent Beta Cell Dynamics in the Male db/db Mice
Louise S. Dalboge et al.
PLOS ONE (2013)
Acute and long-term effects of Roux-en-Y gastric bypass on glucose metabolism in subjects with Type 2 diabetes and normal glucose tolerance
N. B. Jorgensen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2012)
Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure
Chutima Talchai et al.
CELL (2012)
Functional beta-cell maturation is marked by an increased glucose threshold and by expression of urocortin 3
Barak Blum et al.
NATURE BIOTECHNOLOGY (2012)
Defining human ERAD networks through an integrative mapping strategy
John C. Christianson et al.
NATURE CELL BIOLOGY (2012)
C-peptide Predicts the Remission of Type 2 Diabetes After Bariatric Surgery
Wei-Jei Lee et al.
OBESITY SURGERY (2012)
Urocortin 3 Marks Mature Human Primary and Embryonic Stem Cell-Derived Pancreatic Alpha and Beta Cells
Talitha van der Meulen et al.
PLOS ONE (2012)
Weight-Independent Changes in Blood Glucose Homeostasis After Gastric Bypass or Vertical Sleeve Gastrectomy in Rats
Adam P. Chambers et al.
GASTROENTEROLOGY (2011)
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
Mark D. Robinson et al.
BIOINFORMATICS (2010)
Placental lactogens induce serotonin biosynthesis in a subset of mouse beta cells during pregnancy
A. Schraenen et al.
DIABETOLOGIA (2010)
Sleeve Gastrectomy Induces Loss of Weight and Fat Mass in Obese Rats, but Does Not Affect Leptin Sensitivity
Margaret A. Stefater et al.
GASTROENTEROLOGY (2010)
Regulation of pancreatic islet gene expression in mouse islets by pregnancy
B. T. Layden et al.
JOURNAL OF ENDOCRINOLOGY (2010)
Identification of Markers for Newly Formed β-Cells in the Perinatal Period: A Time of Recognized β-Cell Immaturity
Tandy Aye et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2010)
The Roles of ATF3, an Adaptive-Response Gene, in High-Fat-Diet-Induced Diabetes and Pancreatic β-Cell Dysfunction
Erik J. Zmuda et al.
MOLECULAR ENDOCRINOLOGY (2010)
Serotonin regulates pancreatic beta cell mass during pregnancy
Hail Kim et al.
NATURE MEDICINE (2010)
The Transcriptional Response of the Islet to Pregnancy in Mice
Sebastian Rieck et al.
MOLECULAR ENDOCRINOLOGY (2009)
On the origin of the β cell
Jennifer M. Oliver-Krasinski et al.
GENES & DEVELOPMENT (2008)
Effect of weight loss by gastric bypass surgery versus hypocaloric diet on glucose and incretin levels in patients with type 2 diabetes
Blandine Laferrere et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)
Fast unfolding of communities in large networks
Vincent D. Blondel et al.
JOURNAL OF STATISTICAL MECHANICS-THEORY AND EXPERIMENT (2008)
The repression of IRS2 gene by ATF3, a stress-inducible gene, contributes to pancreatic β-cell apoptosis
Dan Li et al.
DIABETES (2008)
Cytokine-induced osteoprotegerin expression protects pancreatic beta cells through p38 mitogen-activated protein kinase signalling against cell death
J. Schrader et al.
DIABETOLOGIA (2007)
Pancreatic deletion of insulin receptor substrate 2 reduces beta and alpha cell mass and impairs glucose homeostasis in mice
J. Cantley et al.
DIABETOLOGIA (2007)
Dietary and genetic control of glucose transporter 2 glycosylation promotes insulin secretion in suppressing diabetes
K Ohtsubo et al.
CELL (2005)
Cyclins D2 and D1 are essential for postnatal pancreatic β-cell growth
JA Kushner et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
The ER chaperone and signaling regulator GRP78/BiP as a monitor of endoplasmic reticulum stress
AS Lee
METHODS (2005)
分享论文
