相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Radiologic evidence that hypothalamic gliosis is improved after bariatric surgery in obese women with type 2 diabetes
Simone van de Sande-Lee et al.
INTERNATIONAL JOURNAL OF OBESITY (2020)
Gastric bypass surgery in a rat model alters the community structure and functional composition of the intestinal microbiota independently of weight loss
Sven-Bastiaan Haange et al.
MICROBIOME (2020)
Obesity: global epidemiology and pathogenesis
Matthias Blueher
NATURE REVIEWS ENDOCRINOLOGY (2019)
Roux-en-Y gastric bypass decreases endotoxemia and inflammatory stress in association with improvements in gut permeability in obese diabetic rats
Yan Guo et al.
JOURNAL OF DIABETES (2019)
Roux-en-Y gastric bypass surgery progressively alters radiologic measures of hypothalamic inflammation in obese patients
Mohammed K. Hankir et al.
JCI INSIGHT (2019)
Microglial Inflammatory Signaling Orchestrates the Hypothalamic Immune Response to Dietary Excess and Mediates Obesity Susceptibility (vol 26, pg 185, 2017)
Martin Valdearcos et al.
CELL METABOLISM (2018)
Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus
Eleni Kyriakou et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Attenuation of diet-induced hypothalamic inflammation following bariatric surgery in female mice
Mary K. Herrick et al.
MOLECULAR MEDICINE (2018)
Alterations of Gut Microbiota After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy in Sprague-Dawley Rats
Yikai Shao et al.
OBESITY SURGERY (2017)
LPS-Induced Low-Grade Inflammation Increases Hypothalamic JNK Expression and Causes Central Insulin Resistance Irrespective of Body Weight Changes
Rodrigo Rorato et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention
Ruixin Liu et al.
NATURE MEDICINE (2017)
Interactions between the microbiota, immune and nervous systems in health and disease
Thomas C. Fung et al.
NATURE NEUROSCIENCE (2017)
Bariatric Surgery versus Intensive Medical Therapy for Diabetes-5-Year Outcomes
Philip R. Schauer et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
Sleeve Gastrectomy Alters Intestinal Permeability in Diet-Induced Obese Mice
Claire Blanchard et al.
OBESITY SURGERY (2017)
Roux-en-Y gastric bypass surgery suppresses hypothalamic PTP1B protein level and alleviates leptin resistance in obese rats
Jia-Yu Liu et al.
EXPERIMENTAL AND THERAPEUTIC MEDICINE (2017)
Knockdown of Tlr4 in the Arcuate Nucleus Improves Obesity Related Metabolic Disorders
Yongli Zhao et al.
SCIENTIFIC REPORTS (2017)
Lipopolysaccharide enters the rat brain by a lipoprotein-mediated transport mechanism in physiological conditions
Alejandra Vargas-Caraveo et al.
SCIENTIFIC REPORTS (2017)
Gastric Bypass Surgery Recruits a Gut PPAR-α-Striatal D1R Pathway to Reduce Fat Appetite in Obese Rats
Mohammed K. Hankir et al.
CELL METABOLISM (2017)
Gut-Brain Cross-Talk in Metabolic Control
Christoffer Clemmensen et al.
CELL (2017)
Heterogeneous vascular permeability and alternative diffusion barrier in sensory circumventricular organs of adult mouse brain
Shoko Morita et al.
CELL AND TISSUE RESEARCH (2016)
Gastric Bypass Surgery but not Caloric Restriction Improves Reproductive Function in Obese Mice
Aaron P. Frank et al.
OBESITY SURGERY (2016)
Persistent microbiome alterations modulate the rate of post-dieting weight regain
Christoph A. Thaiss et al.
NATURE (2016)
Withaferin A is a leptin sensitizer with strong antidiabetic properties in mice
Jaemin Lee et al.
NATURE MEDICINE (2016)
Treatment of Obesity with Celastrol
Junli Liu et al.
CELL (2015)
Diet-Induced Obese Mice Retain Endogenous Leptin Action
Nickki Ottaway et al.
CELL METABOLISM (2015)
Roux-en-Y Gastric Bypass and Vertical Banded Gastroplasty InduceLong-Term Changes on the Human Gut Microbiome Contributing to Fat Mass Regulation
Valentina Tremaroli et al.
CELL METABOLISM (2015)
Liraglutide, leptin and their combined effects on feeding: additive intake reduction through common intracellular signalling mechanisms
S. E. Kanoski et al.
DIABETES OBESITY & METABOLISM (2015)
Weight Loss After RYGB Is Independent of and Complementary to Serotonin 2C Receptor Signaling in Male Mice
Jill S. Carmody et al.
ENDOCRINOLOGY (2015)
Astrocytic TLR4 expression and LPS-induced nuclear translocation of STAT3 in the sensory circumventricular organs of adult mouse brain
Yousuke Nakano et al.
JOURNAL OF NEUROIMMUNOLOGY (2015)
Chronic exposure to Low dose bacterial lipopolysaccharide inhibits leptin signaling in vagal afferent neurons
Claire B. de La Serre et al.
PHYSIOLOGY & BEHAVIOR (2015)
Phytonutrient diet supplementation promotes beneficial Clostridia species and intestinal mucus secretion resulting in protection against enteric infection
Marta Wlodarska et al.
SCIENTIFIC REPORTS (2015)
Leptin deficient ob/ob mice and diet-induced obese mice responded differently to Roux-en-Y bypass surgery
Z. Hao et al.
INTERNATIONAL JOURNAL OF OBESITY (2015)
Impaired Cognition after Stimulation of P2Y1 Receptors in the Rat Medial Prefrontal Cortex
Holger Koch et al.
NEUROPSYCHOPHARMACOLOGY (2015)
A Missing Link in Body Weight Homeostasis: The Catabolic Signal of the Overfed State
Yann Ravussin et al.
CELL METABOLISM (2014)
Hormones and Diet, but Not Body Weight, Control Hypothalamic Microglial Activity
Yuanqing Gao et al.
GLIA (2014)
Cellular insulin resistance disrupts hypothalamic mHypoA-POMC/GFP neuronal signaling pathways
Anaies Nazarians-Armavil et al.
JOURNAL OF ENDOCRINOLOGY (2014)
Connecting leptin signaling to biological function
Margaret B. Allison et al.
JOURNAL OF ENDOCRINOLOGY (2014)
Microglia Dictate the Impact of Saturated Fat Consumption on Hypothalamic Inflammation and Neuronal Function
Martin Valdearcos et al.
CELL REPORTS (2014)
Characterization of the 17 strains of regulatory T cell-inducing human-derived Clostridia
Seiko Narushima et al.
GUT MICROBES (2014)
Plasma Lipopolysaccharide Is Closely Associated With Glycemic Control and Abdominal Obesity Evidence from bariatric surgery
Marius Troseid et al.
DIABETES CARE (2013)
Weight-Independent Effects of Roux-en-Y Gastric Bypass on Glucose Homeostasis via Melanocortin-4 Receptors in Mice and Humans
Juliet F. Zechner et al.
GASTROENTEROLOGY (2013)
Obesity Induces Hypothalamic Endoplasmic Reticulum Stress and Impairs Proopiomelanocortin (POMC) Post-translational Processing
Isin Cakir et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota
Koji Atarashi et al.
NATURE (2013)
Conserved Shifts in the Gut Microbiota Due to Gastric Bypass Reduce Host Weight and Adiposity
Alice P. Liou et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
Commensal Clostridia: leading players in the maintenance of gut homeostasis
Loris R. Lopetuso et al.
GUT PATHOGENS (2013)
Recognition of lipopolysaccharide pattern by TLR4 complexes
Beom Seok Park et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2013)
Saturated fatty acids activate microglia via Toll-like receptor 4/NF-κB signalling
Zhen Wang et al.
BRITISH JOURNAL OF NUTRITION (2012)
Bariatric Surgery and Long-term Cardiovascular Events
Lars Sjostrom et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2012)
Melanocortin-4 Receptor Signaling Is Required for Weight Loss after Gastric Bypass Surgery
Ida J. Hatoum et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)
Obesity is associated with hypothalamic injury in rodents and humans
Joshua P. Thaler et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21
Timo D. Mueller et al.
JOURNAL OF PEPTIDE SCIENCE (2012)
A metagenome-wide association study of gut microbiota in type 2 diabetes
Junjie Qin et al.
NATURE (2012)
Reduction in endotoxemia, oxidative and inflammatory stress, and insulin resistance after Roux-en-Y gastric bypass surgery in patients with morbid obesity and type 2 diabetes mellitus
Scott V. Monte et al.
SURGERY (2012)
Involvement of gut microbiota in the development of low-grade inflammation and type 2 diabetes associated with obesity
Patrice D. Cani et al.
GUT MICROBES (2012)
Responses of Gut Microbiota and Glucose and Lipid Metabolism to Prebiotics in Genetic Obese and Diet-Induced Leptin-Resistant Mice
Amandine Everard et al.
DIABETES (2011)
TAK-242 (Resatorvid), a Small-Molecule Inhibitor of Toll-Like Receptor (TLR) 4 Signaling, Binds Selectively to TLR4 and Interferes with Interactions between TLR4 and Its Adaptor Molecules
Naoko Matsunaga et al.
MOLECULAR PHARMACOLOGY (2011)
Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species
Koji Atarashi et al.
SCIENCE (2011)
Sleeve Gastrectomy Induces Loss of Weight and Fat Mass in Obese Rats, but Does Not Affect Leptin Sensitivity
Margaret A. Stefater et al.
GASTROENTEROLOGY (2010)
IL-6 and IL-10 Anti-Inflammatory Activity Links Exercise to Hypothalamic Insulin and Leptin Sensitivity through IKKβ and ER Stress Inhibition
Eduardo R. Ropelle et al.
PLOS BIOLOGY (2010)
MyD88 Signaling in the CNS Is Required for Development of Fatty Acid-Induced Leptin Resistance and Diet-Induced Obesity
Andre Kleinridders et al.
CELL METABOLISM (2009)
Endoplasmic Reticulum Stress Plays a Central Role in Development of Leptin Resistance
Lale Ozcan et al.
CELL METABOLISM (2009)
Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability
P. D. Cani et al.
GUT (2009)
Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity
Marciane Milanski et al.
JOURNAL OF NEUROSCIENCE (2009)
Central Administration of an Endoplasmic Reticulum Stress Inducer Inhibits the Anorexigenic Effects of Leptin and Insulin
Jong Chul Won et al.
OBESITY (2009)
Hypothalamic IKKβ/NF-κB and ER stress link overnutrition to energy imbalance and obesity
Xiaoqing Zhang et al.
CELL (2008)
Shared principles in NF-κB signaling
Matthew S. Hayden et al.
CELL (2008)
Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
Patrice D. Cani et al.
DIABETES (2008)
Lifestyle and Pharmacological Approaches to Weight Loss: Efficacy and Safety
George A. Bray
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
Umut Oezcan et al.
SCIENCE (2006)
Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2
J Deng et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
U Özcan et al.
SCIENCE (2004)
Lipopolysaccharide (LPS)-binding protein mediates LPS detoxification by chylomicrons
ACE Vreugdenhil et al.
JOURNAL OF IMMUNOLOGY (2003)