相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure
Robert E. Turnbull et al.
NATURE COMMUNICATIONS (2020)
Synergistic Enhancement of Cancer Therapy Using HDAC Inhibitors: Opportunity for Clinical Trials
Lourdes Hontecillas-Prieto et al.
FRONTIERS IN GENETICS (2020)
Recent progress on HDAC inhibitors with dual targeting capabilities for cancer treatment
Xiaopeng Peng et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)
Design of Fluorescent Coumarin-Hydroxamic Acid Derivatives as Inhibitors of HDACs: Synthesis, Anti-Proliferative Evaluation and Docking Studies
Santiago Garcia et al.
MOLECULES (2020)
Emerging role of histone deacetylase inhibitors as anti-breast-cancer agents
Meran Keshawa Ediriweera et al.
DRUG DISCOVERY TODAY (2019)
Cell Cycle Arrest and Cytotoxic Effects of SAHA and RG7388 Mediated through p21WAF1/CIP1 and p27KIP1 in Cancer Cells
Umamaheswari Natarajan et al.
MEDICINA-LITHUANIA (2019)
Structural insight into substrate and inhibitor discrimination by human P-glycoprotein
Amer Alam et al.
SCIENCE (2019)
Chimeric HDAC inhibitors: Comprehensive review on the HDAC-based strategies developed to combat cancer
Heba M. Hesham et al.
MEDICINAL RESEARCH REVIEWS (2018)
Ricolinostat (ACY-1215) suppresses proliferation and promotes apoptosis in esophageal squamous cell carcinoma via miR-30d/PI3K/AKT/mTOR and ERK pathways
Jinlin Cao et al.
CELL DEATH & DISEASE (2018)
Perfluorinated HDAC inhibitors as selective anticancer agents
James W. Walton et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2017)
Breast Cancer Cell Line Classification and Its Relevance with Breast Tumor Subtyping
Xiaofeng Dai et al.
JOURNAL OF CANCER (2017)
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
Antoine Daina et al.
SCIENTIFIC REPORTS (2017)
At the crossroads of cancer stem cells and targeted therapy resistance
Anbang Wang et al.
CANCER LETTERS (2017)
Dissecting structure-activity-relationships of crebinostat: Brain penetrant HDAC inhibitors for neuroepigenetic regulation
Balaram Ghosh et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)
Histone deacetylase 6 structure and molecular basis of catalysis and inhibition
Yang Hai et al.
NATURE CHEMICAL BIOLOGY (2016)
Exploring the 7-oxo-thiazolo[5,4-d]pyrimidine core for the design of new human adenosine A3 receptor antagonists. Synthesis, molecular modeling studies and pharmacological evaluation
Flavia Varano et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)
Histone Deacetylase Inhibitors in Clinical Studies as Templates for New Anticancer Agents
Madhusoodanan Mottamal et al.
MOLECULES (2015)
Histone Deacetylases Positively Regulate Transcription through the Elongation Machinery
Celeste B. Greer et al.
CELL REPORTS (2015)
Synthesis and anticancer activities of thieno[3,2-d]pyrimidines as novel HDAC inhibitors
Qiu Tan et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2014)
New and emerging HDAC inhibitors for cancer treatment
Alison C. West et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
A novel histone deacetylase (HDAC) inhibitor MHY219 induces apoptosis via up-regulation of androgen receptor expression in human prostate cancer cells
Nabanita Patra et al.
BIOMEDICINE & PHARMACOTHERAPY (2013)
Synthesis, ex vivo and in silico studies of 3-cyano-2-pyridone derivatives with vasorelaxant activity
Fernando Hernandez et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
Coumarin-based dual fluorescent spin-probes
Janez Mravljak et al.
TETRAHEDRON LETTERS (2013)
CS055 (Chidamide/HBI-8000), a novel histone deacetylase inhibitor, induces G1 arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells
Ke Gong et al.
BIOCHEMICAL JOURNAL (2012)
Chidamide (CS055/HBI-8000): a new histone deacetylase inhibitor of the benzamide class with antitumor activity and the ability to enhance immune cell-mediated tumor cell cytotoxicity
Zhi-Qiang Ning et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2012)
Involvement of HDAC1 in E-cadherin expression in prostate cancer cells; its implication for cell motility and invasion
Nam Hyun Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Synthesis of N-Hydroxycinnamides Capped with a Naturally Occurring Moiety as Inhibitors of Histone Deacetylase
Wei-Jan Huang et al.
CHEMMEDCHEM (2010)
Modified Cap Group Suberoylanilide Hydroxamic Acid Histone Deacetylase Inhibitor Derivatives Reveal Improved Selective Antileukemic Activity
Chanaz Salmi-Smail et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Docking-enabled pharmacophore model for histone deacetylase 8 inhibitors and its application in anti-cancer drug discovery
Thangapandian Sundarapandian et al.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2010)
SYNTHESIS OF HYDROXAMIC ACIDS BY ACTIVATION OF CARBOXYLIC ACIDS WITH N,N '-CARBONYLDIIMIDAZOLE: EXPLORING THE EFFICIENCY OF THE METHOD
Natalija Usachova et al.
SYNTHETIC COMMUNICATIONS (2010)
N-Hydroxy-1,2-disubstituted-1H-benzimidazol-5-yl acrylamides as novel histone deacetylase inhibitors: Design, synthesis, SAR studies, and in vivo antitumor activity
Haishan Wang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Histone deacetylase inhibitors as a new weapon in the arsenal of differentiation therapies of cancer
Oronza Antonietta Botrugno et al.
CANCER LETTERS (2009)
Development of the pan-DAC inhibitor panobinostat (LBH589): Successes and challenges
Peter Atadja
CANCER LETTERS (2009)
Improved synthesis of histone deacetylase inhibitors (HDIs) (MS-275 and CI-994) and inhibitory effects of HDIs alone or in combination with RAMBAs or retinoids on growth of human LNCaP prostate cancer cells and tumor xenografts
Lalji K. Gediya et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2008)
Triazole-modified histone deacetylase inhibitors as a rapid route to drug discovery
Tracey Pirali et al.
JOURNAL OF COMBINATORIAL CHEMISTRY (2008)
MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo
Marielle Fournel et al.
MOLECULAR CANCER THERAPEUTICS (2008)
Histone deacetylase inhibitors: Overview and perspectives
Milos Dokmanovic et al.
MOLECULAR CANCER RESEARCH (2007)
Histone deacetylases and cancer
M. A. Glozak et al.
ONCOGENE (2007)
Histone deacetylase inhibitors: molecular mechanisms of action
W. S. Xu et al.
ONCOGENE (2007)
Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases
JR Somoza et al.
STRUCTURE (2004)
Epigenetics in human disease and prospects for epigenetic therapy
G Egger et al.
NATURE (2004)
Histone deacetylases and cancer: Causes and therapies
PA Marks et al.
NATURE REVIEWS CANCER (2001)
Suberoylanilide hydroxamic acid as a potential therapeutic agent for human breast cancer treatment
LL Huang et al.
MOLECULAR MEDICINE (2000)
Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation
VM Richon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)