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NATURE REVIEWS NEPHROLOGY (2010)
The mTOR pathway is highly activated in diabetic nephropathy and rapamycin has a strong therapeutic potential
Hiroyuki Mori et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Angiotensin II Induces Connective Tissue Growth Factor and Collagen I Expression via Transforming Growth Factor-β-Dependent and -Independent Smad Pathways The Role of Smad3
Fuye Yang et al.
HYPERTENSION (2009)
Fully Human Monoclonal Antibodies Antagonizing the Glucagon Receptor Improve Glucose Homeostasis in Mice and Monkeys
Hai Yan et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)
The activation of NF-κB and AP-1 in peripheral blood mononuclear cells isolated from patients with diabetic nephropathy
Ji Sun Nam et al.
DIABETES RESEARCH AND CLINICAL PRACTICE (2008)
Role of TSC-mTOR pathway in diabetic nephropathy
Ken Inoki
DIABETES RESEARCH AND CLINICAL PRACTICE (2008)
Long-term follow-up after tight control of blood pressure in type 2 diabetes
Rury R. Holman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Effect of a multifactorial intervention on mortality in type 2 diabetes
Peter Gaede et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
10-year follow-up of intensive glucose control in type 2 diabetes
Rury R. Holman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Peripheral disruption of the grb10 gene enhances insulin signaling and sensitivity in vivo
Lixin Wang et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Glucagon receptor knockout mice are resistant to diet-induced obesity and streptozotocin-mediated beta cell loss and hyperglycaemia
S. L. Conarello et al.
DIABETOLOGIA (2007)
Peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α) regulates triglyceride metabolism by activation of the nuclear receptor FXR
YQ Zhang et al.
GENES & DEVELOPMENT (2004)
Microvascular complications at time of diagnosis of type 2 diabetes are similar among diabetic patients detected by targeted screening and patients newly diagnosed in general practice - The Hoorn Screening Study
AMW Spijkerman et al.
DIABETES CARE (2003)
Substrate specificities of mouse heparan sulphate glucosaminyl 6-O-sulphotransferases
E Smeds et al.
BIOCHEMICAL JOURNAL (2003)
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1α interaction
P Puigserver et al.
NATURE (2003)
Regulation of hepatic fasting response by PPARγ coactivator-1α (PGC-1):: Requirement for hepatocyte nuclear factor 4α in gluconeogenesis
J Rhee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Potentiation of liver X receptor transcriptional activity by peroxisome-proliferator-activated receptor γ co-activator 1α
H Oberkofler et al.
BIOCHEMICAL JOURNAL (2003)
Lower blood glucose, hyperglucagonemia, and pancreatic α cell hyperplasia in glucagon receptor knockout mice
RW Gelling et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes
P Gaede et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Glycemic control in mice with targeted disruption of the glucagon receptor gene
JC Parker et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Biochemistry and molecular cell biology of diabetic complications
M Brownlee
NATURE (2001)
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
S Herzig et al.
NATURE (2001)
UKPDS 50: Risk factors for incidence and progression of retinopathy in Type II diabetes over 6 years from diagnosis
IM Stratton et al.
DIABETOLOGIA (2001)
Insulin/IGF-1 and TNF-alpha stimulate phosphorylation of IRS-1 at inhibitory Ser(307) via distinct pathways
LY Rui et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study
IM Stratton et al.
BMJ-BRITISH MEDICAL JOURNAL (2000)
The functional significance of Shc in insulin signaling as a substrate of the insulin receptor
T Sasaoka et al.
ENDOCRINE JOURNAL (2000)
The c-Jun NH2-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser307
V Aguirre et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)