期刊
NANOMATERIALS
卷 11, 期 6, 页码 -出版社
MDPI
DOI: 10.3390/nano11061448
关键词
carbon dots; carbon quantum dots; nanoparticles; fluorescence; bioimaging; sensing; super-resolution
类别
资金
- National Science Foundation [CBET 1849063]
Carbon dots are a type of fluorescent nanoparticle with biocompatibility and diversity, useful for biomedical applications such as fluorescence imaging and sensors, as well as for drug delivery and photodynamic therapy in other fields.
Carbon dots (CDs) are a particularly useful type of fluorescent nanoparticle that demonstrate biocompatibility, resistance to photobleaching, as well as diversity in composition and characteristics amongst the different types available. There are two main morphologies of CDs: Disk-shaped with 1-3 stacked sheets of aromatic carbon rings and quasi-spherical with a core-shell arrangement having crystalline and amorphous properties. They can be synthesized from various potentially environmentally friendly methods including hydrothermal carbonization, microwaving, pyrolysis or combustion, and are then purified via one or more methods. CDs can have either excitation wavelength-dependent or -independent emission with each having their own benefits in microscopic fluorescent imaging. Some CDs have an affinity for a particular cell type, organelle or chemical. This property allows the CDs to be used as sensors in a biological environment and can even provide quantitative information if the quenching or intensity of their fluorescence is dependent on the concentration of the analyte. In addition to fluorescent imaging, CDs can also be used for other applications including drug delivery, quality control, photodynamic therapy, and photocatalysis.
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