期刊
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
卷 -, 期 172, 页码 -出版社
JOURNAL OF VISUALIZED EXPERIMENTS
DOI: 10.3791/62007
关键词
-
资金
- German Research Foundation (DFG) [HO2581/4-1]
- National Science Foundation of China (NSFC) [81760291]
The study presents a modified surgical technique for heterotopic abdominal heart transplantation in mice, using the intrathoracic inferior vena cava for anastomosis to improve success rates.
The surgical technique of heterotopic abdominal heart transplantation in mice is a standard model for research in transplantation immunology. Here, the established technique for a modified blood circuit reconstruction in a heterotopic abdominal heart transplantation model is presented. This method uses the intrathoracic inferior vena cava (IIVC) instead of the pulmonary artery of the donor heart for the anastomosis to the inferior vena cava of the recipient. It is facilitating and improving success rates for abdominal heart transplantation in mice.
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