4.6 Review

ATM's Role in the Repair of DNA Double-Strand Breaks

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Multidisciplinary Sciences

Loop extrusion as a mechanism for formation of DNA damage repair foci

Coline Arnould et al.

Summary: The repair of DNA double-strand breaks is essential for maintaining genome integrity. This study demonstrates the functional role of topologically associating domains in establishing gamma H2AX-53BP1 chromatin domains, involving cohesin-mediated loop extrusion on both sides of the DSB.

NATURE (2021)

Article Multidisciplinary Sciences

ATM controls the extent of DNA end resection by eliciting sequential posttranslational modifications of CtIP

Jinhua Han et al.

Summary: This study identifies a novel regulatory mechanism that modulates the activity of CtIP at DSBs and the extent of end resection through ATM-dependent sequential posttranslational modification of CtIP.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

Review Cell Biology

53BP1: a DSB escort

Zachary Mirman et al.

GENES & DEVELOPMENT (2020)

Article Multidisciplinary Sciences

DNA double-strand breaks induce H2Ax phosphorylation domains in a contact-dependent manner

Patrick L. Collins et al.

NATURE COMMUNICATIONS (2020)

Article Biochemistry & Molecular Biology

ATM antagonizes NHEJ proteins assembly and DNA-ends synapsis at single-ended DNA double strand breaks

Sebastien Britton et al.

NUCLEIC ACIDS RESEARCH (2020)

Article Biochemistry & Molecular Biology

NBS1 promotes the endonuclease activity of the MRE11-RAD50 complex by sensing CtIP phosphorylation

Roopesh Anand et al.

EMBO JOURNAL (2019)

Review Biochemistry & Molecular Biology

Shieldin - the protector of DNA ends

Dheva Setiaputra et al.

EMBO REPORTS (2019)

Letter Cell Biology

Structural insights into the activation of ATM kinase

Jianxiong Xiao et al.

CELL RESEARCH (2019)

Article Biochemistry & Molecular Biology

UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors

Ron D. Jachimowicz et al.

Article Biochemistry & Molecular Biology

Repression of Transcription at DNA Breaks Requires Cohesin throughout Interphase and Prevents Genome Instability

Cornelia Meisenberg et al.

MOLECULAR CELL (2019)

Article Biochemistry & Molecular Biology

ATM directs DNA damage responses and proteostasis via genetically separable pathways

Ji-Hoon Lee et al.

SCIENCE SIGNALING (2018)

Article Biochemistry & Molecular Biology

ATM directs DNA damage responses and proteostasis via genetically separable pathways

Ji-Hoon Lee et al.

SCIENCE SIGNALING (2018)

Article Biochemistry & Molecular Biology

Regulation of the DNA Damage Response by DNA-PKcs Inhibitory Phosphorylation of ATM

Yi Zhou et al.

MOLECULAR CELL (2017)

Review Biotechnology & Applied Microbiology

Regulation of repair pathway choice at two-ended DNA double-strand breaks

Atsushi Shibata

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2017)

Article Multidisciplinary Sciences

Structures of closed and open conformations of dimeric human ATM

Domagoj Baretic et al.

SCIENCE ADVANCES (2017)

Article Cell Biology

Structure of the human dimeric ATM kinase

Wilson C. Y. Lau et al.

CELL CYCLE (2016)

Article Biochemistry & Molecular Biology

Phosphorylated CtIP Functions as a Co-factor of the MRE11-RAD50-NBS1 Endonuclease in DNA End Resection

Roopesh Anand et al.

MOLECULAR CELL (2016)

Article Cell Biology

SCAI promotes DNA double-strand break repair in distinct chromosomal contexts

Rebecca Kring Hansen et al.

NATURE CELL BIOLOGY (2016)

Article Multidisciplinary Sciences

Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks

Pauline Chanut et al.

NATURE COMMUNICATIONS (2016)

Article Biochemistry & Molecular Biology

Involvement of ATM in homologous recombination after end resection and RAD51 nucleofilament formation

A. Bakr et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Oncology

DNA Double-strand Break Repair in a Cellular Context

A. Shibata et al.

CLINICAL ONCOLOGY (2014)

Article Biochemistry & Molecular Biology

DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities

Atsushi Shibata et al.

MOLECULAR CELL (2014)

Article Biochemistry & Molecular Biology

Co-operation of BRCA1 and POH1 relieves the barriers posed by 53BP1 and RAP80 to resection

Andreas Kakarougkas et al.

NUCLEIC ACIDS RESEARCH (2013)

Article Biochemistry & Molecular Biology

Opposing roles for 53BP1 during homologous recombination

Andreas Kakarougkas et al.

NUCLEIC ACIDS RESEARCH (2013)

Review Biochemistry & Molecular Biology

The Heterochromatic Barrier to DNA Double Strand Break Repair: How to Get the Entry Visa

Aaron A. Goodarzi et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2012)

Review Biochemistry & Molecular Biology

Understanding the limitations of radiation-induced cell cycle checkpoints

Dorothee Deckbar et al.

CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Factors determining DNA double-strand break repair pathway choice in G2 phase

Atsushi Shibata et al.

EMBO JOURNAL (2011)

Article Biochemistry & Molecular Biology

KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response

Aaron A. Goodarzi et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Signals from the Nucleus: Activation of NF-κB by Cytosolic ATM in the DNA Damage Response

Kamyar Hadian et al.

SCIENCE SIGNALING (2011)

Article Biochemistry & Molecular Biology

ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks

Niraj M. Shanbhag et al.

Article Biochemistry & Molecular Biology

53BP1 promotes ATM activity through direct interactions with the MRN complex

Ji-Hoon Lee et al.

EMBO JOURNAL (2010)

Article Multidisciplinary Sciences

ATM Activation by Oxidative Stress

Zhi Guo et al.

SCIENCE (2010)

Article Biochemistry & Molecular Biology

ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2

Andrea Beucher et al.

EMBO JOURNAL (2009)

Article Biochemistry & Molecular Biology

Human CtIP Mediates Cell Cycle Control of DNA End Resection and Double Strand Break Repair

Pablo Huertas et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Single-Stranded DNA Orchestrates an ATM-to-ATR Switch at DNA Breaks

Bunsyo Shiotani et al.

MOLECULAR CELL (2009)

Article Biochemistry & Molecular Biology

ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin

Aaron A. Goodarzi et al.

MOLECULAR CELL (2008)

Article Multidisciplinary Sciences

Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase

Nadine K. Kolas et al.

SCIENCE (2007)

Article Biochemistry & Molecular Biology

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

Michael S. Y. Huen et al.

Article Multidisciplinary Sciences

Human CtIP promotes DNA end resection

Alessandro A. Sartori et al.

NATURE (2007)

Article Cell Biology

DNA damage checkpoints: from initiation to recovery or adaptation

Jiri Bartek et al.

CURRENT OPINION IN CELL BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Requirement of the MRN complex for ATM activation by DNA damage

T Uziel et al.

EMBO JOURNAL (2003)

Article Cell Biology

DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1

O Fernandez-Capetillo et al.

NATURE CELL BIOLOGY (2002)