期刊
FRONTIERS IN PHYSIOLOGY
卷 12, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fphys.2021.700129
关键词
intestine; autonomic nerve system; enteric nervous system; cellular proliferation; intestinal disease
类别
资金
- Nationalnbsp
- Natural Science Foundation of China [81960104, 81860026]
- Keynbsp
- Ramp
- Dnbsp
- plan ofnbsp
- Jiangxinbsp
- Provincial Science and Technology Department [20192BBG70043, 20202ACB206009]
- Interdisciplinary Innovation Fund ofnbsp
- Natural Science,nbsp
- Nanchang University [9166-27060003-YB13, 202010403062]
- Project of Traditional Chinese Medicine innbsp
- Jiangxinbsp
- Province [2019A176]
- National undergradute innovation and entrepreneurship trainingnbsp
- program [202010403062]
The intestine is composed of various types of cells that play important roles in digestion, absorption, neuroendocrine, and immune functions. The autonomic nervous system regulates cellular proliferation and function in the intestine. Understanding the distribution and function of the autonomic nervous system in the intestine could be helpful in treating intestinal diseases.
Intestine is composed of various types of cells including absorptive epithelial cells, goblet cells, endocrine cells, Paneth cells, immunological cells, and so on, which play digestion, absorption, neuroendocrine, immunological function. Intestine is innervated with extrinsic autonomic nerves and intrinsic enteric nerves. The neurotransmitters and counterpart receptors are widely distributed in the different intestinal cells. Intestinal autonomic nerve system includes sympathetic and parasympathetic nervous systems, which regulate cellular proliferation and function in intestine under physiological and pathophysiological conditions. Presently, distribution and functional characteristics of autonomic nervous system in intestine were reviewed. How autonomic nervous system regulates intestinal cell proliferation was discussed. Function of autonomic nervous system on intestinal diseases was extensively reviewed. It might be helpful to properly manipulate autonomic nervous system during treating different intestinal diseases.
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