Systemic Corticosteroid Administration in Coronavirus Disease 2019 Outcomes: An Umbrella Meta-Analysis Incorporating Both Mild and Pulmonary Fibrosis-Manifested Severe Disease

Editorial Material Emergency Medicine

The influence of corticosteroid on patients with COVID-19 infection: A meta-analysis

Yushu Wang et al.

AMERICAN JOURNAL OF EMERGENCY MEDICINE (2021)

添加到收藏夹

Editorial Material Medicine, General & Internal

The RECOVERY Platform

Sharon-Lise T. Normand

NEW ENGLAND JOURNAL OF MEDICINE (2021)

添加到收藏夹

Review Virology

Are the steroids a blanket solution for COVID-19? A systematic review and meta-analysis

Soumya Sarkar et al.

Summary: Studies on the impact of systemic glucocorticoids in COVID-19 patients showed no significant reduction in mortality, duration of hospital stay, or period of viral shedding. The results are heterogeneous and further randomized controlled trials are needed to confirm the effectiveness of systemic steroid therapy in COVID-19 patients.

JOURNAL OF MEDICAL VIROLOGY (2021)

添加到收藏夹

Article Respiratory System

Early Use of Corticosteroid May Prolong SARS-CoV-2 Shedding in Non-Intensive Care Unit Patients with COVID-19 Pneumonia: A Multicenter, Single-Blind, Randomized Control Trial

Xiao Tang et al.

Summary: The study did not find a benefit of short-term early use of corticosteroids in treating patients with COVID-19 pneumonia in terms of clinical deterioration, but it may prolong the shedding of the virus. The number of immune cells was significantly reduced in the treatment group.

RESPIRATION (2021)

添加到收藏夹

Article Critical Care Medicine

Impact of Corticosteroids in Coronavirus Disease 2019 Outcomes Systematic Review and Meta-analysis

Edison J. Cano et al.

Summary: A systematic review of literature on corticosteroids and COVID-19 found evidence of mortality benefit in severely ill COVID-19 patients treated with corticosteroids. However, there were no significant differences in outcomes between high-dose and low-dose corticosteroid regimens. Low-dose corticosteroids do not appear to significantly impact the duration of SARS-CoV-2 viral shedding based on emerging evidence. Further high-quality clinical trials are needed to determine the most beneficial timing and dosing for corticosteroids in the rapidly evolving global pandemic.

CHEST (2021)

添加到收藏夹

Article Anesthesiology

Corticosteroids for Patients With Coronavirus Disease 2019 (COVID-19) With Different Disease Severity: A Meta-Analysis of Randomized Clinical Trials

Laura Pasin et al.

Summary: The efficacy and safety of corticosteroids in patients with COVID-19 are still debated. Recent trials have shown that corticosteroids may be beneficial for severely ill patients but should be discouraged in those not requiring oxygen therapy. Further clinical trials are needed before widespread implementation of this treatment.

JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA (2021)

添加到收藏夹

Article Infectious Diseases

Methylprednisolone or dexamethasone, which one is superior corticosteroid in the treatment of hospitalized COVID-19 patients: a triple-blinded randomized controlled trial

Keivan Ranjbar et al.

Summary: The study demonstrated that methylprednisolone was more effective than dexamethasone in hospitalized hypoxic COVID-19 patients, with better clinical status, shorter hospital stay, and lower need for a ventilator in the intervention group.

BMC INFECTIOUS DISEASES (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

No clinical benefit of high dose corticosteroid administration in patients with COVID-19: A preliminary report of a randomized clinical trial

Hamidreza Jamaati et al.

Summary: The study evaluated the clinical effects of dexamethasone administration in patients with mild to moderate ARDS due to COVID-19. Results showed no significant clinical benefit of corticosteroid administration in these patients.

EUROPEAN JOURNAL OF PHARMACOLOGY (2021)

添加到收藏夹

Article Multidisciplinary Sciences

A pneumonia outbreak associated with a new coronavirus of probable bat origin

Peng Zhou et al.

NATURE (2020)

添加到收藏夹

Review Allergy

Immune response to SARS-CoV-2 and mechanisms of immunopathological changes in COVID-19

Ahmet Kursat Azkur et al.

ALLERGY (2020)

添加到收藏夹

Article Medicine, General & Internal

Efficacy and safety of corticosteroids in COVID-19 based on evidence for COVID-19, other coronavirus infections, influenza, community-acquired pneumonia and acute respiratory distress syndrome: a systematic review and meta-analysis

Zhikang Ye et al.

CANADIAN MEDICAL ASSOCIATION JOURNAL (2020)

添加到收藏夹

Letter Respiratory System

Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2: a prospective cohort study

Rong-Hui Du et al.

EUROPEAN RESPIRATORY JOURNAL (2020)

添加到收藏夹

Article Critical Care Medicine

Dexamethasone treatment for the acute respiratory distress syndrome: a multicentre, randomised controlled trial

Jesus Villar et al.

LANCET RESPIRATORY MEDICINE (2020)

添加到收藏夹

Article Medicine, General & Internal

Features of 20133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study

Annemarie B. Docherty et al.

BMJ-BRITISH MEDICAL JOURNAL (2020)

添加到收藏夹

Review Oncology

Effectiveness and safety of glucocorticoids to treat COVID-19: a rapid review and meta-analysis

Shuya Lu et al.

ANNALS OF TRANSLATIONAL MEDICINE (2020)

添加到收藏夹

Review Immunology

COVID-19: Immunology and treatment options

Susanna Felsenstein et al.

CLINICAL IMMUNOLOGY (2020)

添加到收藏夹

Review Medicine, General & Internal

Drug treatments for covid-19: living systematic review and network meta-analysis

Reed A. C. Siemieniuk et al.

BMJ-BRITISH MEDICAL JOURNAL (2020)

添加到收藏夹

Article Medicine, General & Internal

Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19 A Meta-analysis

Jonathan A. C. Sterne et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

添加到收藏夹

Review Pharmacology & Pharmacy

Efficacy and Safety of Corticosteroid Treatment in Patients With COVID-19: A Systematic Review and Meta-Analysis

Wenwen Cheng et al.

FRONTIERS IN PHARMACOLOGY (2020)

添加到收藏夹

Review Public, Environmental & Occupational Health

Association of corticosteroids use and outcomes in COVID-19 patients: A systematic review and meta-analysis

Haytham Tlayjeh et al.

JOURNAL OF INFECTION AND PUBLIC HEALTH (2020)

添加到收藏夹

Article Pharmacology & Pharmacy

A Retrospective Study on the Use of Chinese Patent Medicine in 24 Medical Institutions for COVID-19 in China

Nan Zhang et al.

FRONTIERS IN PHARMACOLOGY (2020)

添加到收藏夹

Review Critical Care Medicine

Corticosteroid use in COVID-19 patients: a systematic review and meta-analysis on clinical outcomes

Judith van Paassen et al.

CRITICAL CARE (2020)

添加到收藏夹

Review Medicine, General & Internal

Antiviral agents, glucocorticoids, antibiotics, and intravenous immunoglobulin in 1142 patients with coronavirus disease 2019: a systematic review and meta-analysis

Lei Pei et al.

POLISH ARCHIVES OF INTERNAL MEDICINE-POLSKIE ARCHIWUM MEDYCYNY WEWNETRZNEJ (2020)

添加到收藏夹

Review Immunology

The trinity of COVID-19: immunity, inflammation and intervention

Matthew Zirui Tay et al.

NATURE REVIEWS IMMUNOLOGY (2020)

添加到收藏夹

Article Critical Care Medicine

Prolonged low-dose methylprednisolone treatment is highly effective in reducing duration of mechanical ventilation and mortality in patients with ARDS

Gianfranco Umberto Meduri et al.

JOURNAL OF INTENSIVE CARE (2018)

添加到收藏夹

Article Critical Care Medicine

Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017

Djillali Annane et al.

INTENSIVE CARE MEDICINE (2017)

添加到收藏夹

Review Critical Care Medicine

Critical illness-related corticosteroid insufficiency (CIRCI): a narrative review from a Multispecialty Task Force of the Society of Critical Care Medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM)

Djillali Annane et al.

INTENSIVE CARE MEDICINE (2017)

添加到收藏夹

Review Medicine, General & Internal

Obesity and gynaecological and obstetric conditions: umbrella review of the literature

Ilkka Kalliala et al.

BMJ-BRITISH MEDICAL JOURNAL (2017)

添加到收藏夹

Review Medicine, General & Internal

Obesity and gynaecological and obstetric conditions: umbrella review of the literature

Ilkka Kalliala et al.

BMJ-BRITISH MEDICAL JOURNAL (2017)

添加到收藏夹

Article Critical Care Medicine

The clinical practice guideline for the management of ARDS in Japan

Satoru Hashimoto et al.

JOURNAL OF INTENSIVE CARE (2017)

添加到收藏夹

Review Critical Care Medicine

Prolonged glucocorticoid treatment is associated with improved ARDS outcomes: analysis of individual patients' data from four randomized trials and trial-level meta-analysis of the updated literature

G. Umberto Meduri et al.

INTENSIVE CARE MEDICINE (2016)

添加到收藏夹

Editorial Material Mathematics, Interdisciplinary Applications

Clarifications on the application and interpretation of the test for excess significance and its extensions

John P. A. Ioannidis

JOURNAL OF MATHEMATICAL PSYCHOLOGY (2013)

添加到收藏夹

Article Medicine, General & Internal

Interpretation of random effects meta-analyses

Richard D. Riley et al.

BMJ-BRITISH MEDICAL JOURNAL (2011)

添加到收藏夹

Article Medicine, General & Internal

Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials

Jonathan A. C. Sterne et al.

BMJ-BRITISH MEDICAL JOURNAL (2011)

添加到收藏夹

Article Medicine, Research & Experimental

An exploratory test for an excess of significant findings

John P. A. Ioannidis et al.

CLINICAL TRIALS (2007)

添加到收藏夹

Systemic Corticosteroid Administration in Coronavirus Disease 2019 Outcomes: An Umbrella Meta-Analysis Incorporating Both Mild and Pulmonary Fibrosis-Manifested Severe Disease

相关参考文献

导出引文

分享论文