期刊
FEBS OPEN BIO
卷 11, 期 7, 页码 1812-1813出版社
WILEY
DOI: 10.1002/2211-5463.13217
关键词
biomarker; gastric cancer; miRNA; miR-194; prognosis; the cancer genome atlas
The study identifies miR-194 as a potential biomarker for a more favorable prognosis in gastric cancer, due to its downregulation of CCND1, a key protein for cancer development. Early detection and accurate assessment of treatment options play a crucial role in improving survival rates for gastric cancer patients.
Important factors in combating cancer are early detection and accurate assessment of the best course of treatment. In a study published in this issue, Wang et al. identify possible miRNA biomarkers for improved determination of gastric cancer stage and prognosis. In particular, they show increased miR-194 levels are a predictor of more favourable gastric cancer prognosis, at least in part due to miR-194 downregulating production of a key protein for cancer development: CCND1.
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