4.6 Review

Recent Progress in Catalytic Synthesis of 1,2,3-Triazoles

期刊

CATALYSTS
卷 11, 期 9, 页码 -

出版社

MDPI
DOI: 10.3390/catal11091120

关键词

1; 2; 3-triazoles; click chemistry; 1; 3-dipolar cycloaddition; Huisgen reactions; triazole synthesis

资金

  1. University of Calabria and Calabria Region [H28D19000040006]
  2. Italian Ministry of University and Research (MUR) [PON ARS01_00568, CONCESSIONE RNA-COR: 4646672 CUP: B29C20000360005]

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This review summarizes the progress achieved in the synthesis of 1,2,3-triazoles from 2015 to today, focusing particularly on the development of new catalytic and eco-compatible approaches. The report is subdivided based on the degree of functionalization of the molecules, with emphasis on the role of the catalyst employed for each specific approach.
1,2,3-triazoles represent a functional heterocyclic core that has been at the center of modern organic chemistry since the beginning of click chemistry. Being a versatile framework, such an aromatic ring can be observed in uncountable molecules useful in medicine and photochemistry, just to name a few. This review summarizes the progress achieved in their synthesis from 2015 to today, with particular emphasis on the development of new catalytic and eco-compatible approaches. In doing so, we subdivided the report based on their degree of functionalization and, for each subparagraph, we outlined the role of the catalyst employed.

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