期刊
BRAIN AND BEHAVIOR
卷 11, 期 10, 页码 -出版社
WILEY
DOI: 10.1002/brb3.2302
关键词
experimental autoimmune encephalomyelitis; ganglion cell layer; multiple sclerosis; optical coherence tomography; retinal nerve fiber layer
资金
- National Natural Science Foundation of China [81873759]
The study demonstrates the potential of optical coherence tomography (OCT) in monitoring and diagnosing multiple sclerosis (MS) by showing changes in retinal structures that reflect the progression of the disease. OCT parameters serve as noninvasive and sensitive indicators for assessing neurodegeneration and inflammation in MS.
This study explores the use of optical coherence tomography (OCT) to monitor and diagnose multiple sclerosis (MS). The analysis of reduced total macular volume and peripapillary retinal nerve fiber layer thinning are shown. The severity of these defects increases as MS progresses, reflecting the progressive degeneration of nerve fibers and retinal ganglion cells. The OCT parameters are noninvasive, sensitive indicators that can be used to assess the progression of neurodegeneration and inflammation in MS.
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