Recent Advances in Selected Asymmetric Reactions Promoted by Chiral Catalysts: Cyclopropanations, Friedel-Crafts, Mannich, Michael and Other Zinc-Mediated Processes-An Update

The main purpose of this review article is to present selected asymmetric synthesis reactions in which chemical and stereochemical outcomes are dependent on the use of an appropriate chiral catalyst. Optically pure or enantiomerically enriched products of such transformations may find further applications in various fields. Among an extremely wide variety of asymmetric reactions catalyzed by chiral systems, we are interested in: asymmetric cyclopropanation, Friedel-Crafts reaction, Mannich and Michael reaction, and other stereoselective processes conducted in the presence of zinc ions. This paper describes the achievements of the above-mentioned asymmetric transformations in the last three years. The choice of reactions is related to the research that has been carried out in our laboratory for many years.

Automated summary

This review article presents the achievements of selected asymmetric synthesis reactions in the last three years, focusing on asymmetric cyclopropanation, Friedel-Crafts reaction, Mannich and Michael reaction, and other stereoselective processes catalyzed by chiral systems. These transformations rely on the use of appropriate chiral catalysts to control both the chemical and stereochemical outcomes, leading to optically pure or enantiomerically enriched products with potential applications in various fields.