相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types
Jin Li et al.
EMBO REPORTS (2016)
Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function
H. Efsun Arda et al.
CELL METABOLISM (2016)
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes
Asa Segerstolpe et al.
CELL METABOLISM (2016)
Single-Cell Transcriptomics of the Human Endocrine Pancreas
Yue J. Wang et al.
DIABETES (2016)
β-Cell Deficit in Obese Type 2 Diabetes, a Minor Role of β-Cell Dedifferentiation and Degranulation
Alexandra E. Butler et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2016)
Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes
Francesca Cinti et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2016)
Identification of proliferative and mature β-cells in the islets of Langerhans
Erik Bader et al.
NATURE (2016)
Use of the Fluidigm C1 platform for RNA sequencing of single mouse pancreatic islet cells
Yurong Xin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Human islets contain four distinct subtypes of β cells
Craig Dorrell et al.
NATURE COMMUNICATIONS (2016)
Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets
Michael R. DiGruccio et al.
MOLECULAR METABOLISM (2016)
Classification of low quality cells from single-cell RNA-seq data
Tomislav Ilicic et al.
GENOME BIOLOGY (2016)
dendextend: an R package for visualizing, adjusting and comparing trees of hierarchical clustering
Tal Galili
BIOINFORMATICS (2015)
TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic β-Cells
Laura Marroqui et al.
DIABETES (2015)
Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets
David M. Blodgett et al.
DIABETES (2015)
DLK1 Regulates Whole-Body Glucose Metabolism: A Negative Feedback Regulation of the Osteocalcin-Insulin Loop
Basem M. Abdallah et al.
DIABETES (2015)
Defining cell types and states with single-cell genomics
Cole Trapnell
GENOME RESEARCH (2015)
Recent advances in understanding the genetic architecture of type 2 diabetes
Karen L. Mohlke et al.
HUMAN MOLECULAR GENETICS (2015)
A cis-eQTL in PFKFB2 is associated with diabetic nephropathy, adiposity and insulin secretion in American Indians
Yunhua L. Muller et al.
HUMAN MOLECULAR GENETICS (2015)
Soluble CD36 in plasma and urine: A plausible prognostic marker for diabetic nephropathy
Thomas Michael Shiju et al.
JOURNAL OF DIABETES AND ITS COMPLICATIONS (2015)
The role of pancreatic polypeptide in the regulation of energy homeostasis
Neeta Khandekar et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2015)
Epigenetic Regulation of the lncRNA MEG3 and Its Target c-MET in Pancreatic Neuroendocrine Tumors
Sita D. Modali et al.
MOLECULAR ENDOCRINOLOGY (2015)
Plasma butyrylcholinesterase regulates ghrelin to control aggression
Vicky Ping Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors
Martijn van de Bunt et al.
PLOS GENETICS (2015)
A Common Functional Regulatory Variant at a Type 2 Diabetes Locus Upregulates ARAP1 Expression in the Pancreatic Beta Cell
Jennifer R. Kulzer et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2014)
Pancreatic β Cell Dedifferentiation in Diabetes and Redifferentiation following Insulin Therapy
Zhiyu Wang et al.
CELL METABOLISM (2014)
Epigenetic Regulation of the DLK1-MEG3 MicroRNA Cluster in Human Type 2 Diabetic Islets
Vasumathi Kameswaran et al.
CELL METABOLISM (2014)
Pancreatic Polypeptide Controls Energy Homeostasis via Npy6r Signaling in the Suprachiasmatic Nucleus in Mice
Ernie Yulyaningsih et al.
CELL METABOLISM (2014)
Control of Insulin Secretion by Cholinergic Signaling in the Human Pancreatic Islet
Judith Molina et al.
DIABETES (2014)
β-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment
Philippe A. Halban et al.
DIABETES CARE (2014)
The diabetes gene Hhex maintains δ-cell differentiation and islet function
Jia Zhang et al.
GENES & DEVELOPMENT (2014)
MARIS: Method for Analyzing RNA following Intracellular Sorting
Sinisa Hrvatin et al.
PLOS ONE (2014)
Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism
Joao Fadista et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Many faces of monogenic diabetes
Valerie M. Schwitzgebel
JOURNAL OF DIABETES INVESTIGATION (2014)
Genome-Wide DNA Methylation Analysis of Human Pancreatic Islets from Type 2 Diabetic and Non-Diabetic Donors Identifies Candidate Genes That Influence Insulin Secretion
Tasnim Dayeh et al.
PLOS GENETICS (2014)
Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets
T. A. Dayeh et al.
DIABETOLOGIA (2013)
Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome
Alexandra C. Nica et al.
GENOME RESEARCH (2013)
Epigenomic plasticity enables human pancreatic α to β cell reprogramming
Nuria C. Bramswig et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation
Frederick J. Sheedy et al.
NATURE IMMUNOLOGY (2013)
Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants
Stephen C. J. Parker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
The origin of circulating CD36 in type 2 diabetes
M. J. Alkhatatbeh et al.
NUTRITION & DIABETES (2013)
Genes Involved in Type 1 Diabetes: An Update
Marina Bakay et al.
GENES (2013)
Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure
Chutima Talchai et al.
CELL (2012)
A Systems Genetics Approach Identifies Genes and Pathways for Type 2 Diabetes in Human Islets
Jalal Taneera et al.
CELL METABOLISM (2012)
Transient Neonatal Diabetes Mellitus Gene Zac1 Impairs Insulin Secretion in Mice through Rasgrf1
Anke Hoffmann et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes
Sofia A. Andersson et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2012)
Fast gapped-read alignment with Bowtie 2
Ben Langmead et al.
NATURE METHODS (2012)
RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
Bo Li et al.
BMC BIOINFORMATICS (2011)
Convergence of the Insulin and Serotonin Programs in the Pancreatic β-Cell
Yasuharu Ohta et al.
DIABETES (2011)
Transcriptomes of the major human pancreatic cell types
C. Dorrell et al.
DIABETOLOGIA (2011)
Islet-1 Regulates Arx Transcription during Pancreatic Islet α-Cell Development
Jingxuan Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Differences between Human and Rodent Pancreatic Islets LOW PYRUVATE CARBOXYLASE, ATP CITRATE LYASE, AND PYRUVATE CARBOXYLATION AND HIGH GLUCOSE-STIMULATED ACETOACETATE IN HUMAN PANCREATIC ISLETS
Michael J. MacDonald et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Pancreatic ductal cells in development, regeneration, and neoplasia
Maximilian Reichert et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Isolation of mouse pancreatic alpha, beta, duct and acinar populations with cell surface markers
Craig Dorrell et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2011)
ISLET AMYLOID POLYPEPTIDE, ISLET AMYLOID, AND DIABETES MELLITUS
Per Westermark et al.
PHYSIOLOGICAL REVIEWS (2011)
The pyruvate carboxylase-pyruvate dehydrogenase axis in islet pyruvate metabolism Going round in circles?
Mary C. Sugden et al.
ISLETS (2011)
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
Mark D. Robinson et al.
BIOINFORMATICS (2010)
Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
Sven Heinz et al.
MOLECULAR CELL (2010)
The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes
Chris Wallace et al.
NATURE GENETICS (2010)
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
Josee Dupuis et al.
NATURE GENETICS (2010)
Genomewide Association Studies and Assessment of the Risk of Disease
Teri A. Manolio
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Pancreatic Stellate Cell Models for Transcriptional Studies of Desmoplasia-Associated Genes
Angela Mathison et al.
PANCREATOLOGY (2010)
Gene Expression Profiles of Beta-Cell Enriched Tissue Obtained by Laser Capture Microdissection from Subjects with Type 2 Diabetes
Lorella Marselli et al.
PLOS ONE (2010)
Congenital Hyperinsulinism due to mutations in HNF4A and HADH
Ritika R. Kapoor et al.
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS (2010)
Glucose sensing in the pancreatic beta cell: a computational systems analysis
Leonid E. Fridlyand et al.
THEORETICAL BIOLOGY AND MEDICAL MODELLING (2010)
Short-chain 3-hydroxyacyl-CoA dehydrogenase is a negative regulator of insulin secretion in response to fuel and non-fuel stimuli in INS832/13 β-cells
Emilie Pepin et al.
JOURNAL OF DIABETES (2010)
GAGE: generally applicable gene set enrichment for pathway analysis
Weijun Luo et al.
BMC BIOINFORMATICS (2009)
Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion
Valeriya Lyssenko et al.
NATURE GENETICS (2009)
Intracellular Serotonin Modulates Insulin Secretion from Pancreatic β-Cells by Protein Serotonylation
Nils Paulmann et al.
PLOS BIOLOGY (2009)
Topographical associations between islet endocrine cells and duct epithelial cells in the adult human pancreas
Hai-Lu Zhao et al.
CLINICAL ENDOCRINOLOGY (2008)
Human serum levels of fetal antigen 1 (FA1/Dlk1) increase with obesity, are negatively associated with insulin sensitivity and modulate inflammation in vitro
M. R. Chacon et al.
INTERNATIONAL JOURNAL OF OBESITY (2008)
How to interpret a genome-wide association study
Thomas A. Pearson et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2008)
α-isopropylmalate, a leucine biosynthesis intermediate in yeast, is transported by the mitochondrial oxalacetate carrier
Carlo M. T. Marobbio et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Mutations in UCP2 in Congenital Hyperinsulinism Reveal a Role for Regulation of Insulin Secretion
M. Mar Gonzalez-Barroso et al.
PLOS ONE (2008)
Isolation of major pancreatic cell types and long-term culture-initiating cells using novel human surface markers
Craig Dorrell et al.
STEM CELL RESEARCH (2008)
Embryonic endocrine pancreas and mature β cells acquire α and PP cell phenotypes upon Arx misexpression
Patrick Collombat et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Islet β cell failure in type 2 diabetes
Marc Prentki et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Antibody inhibition of synaptosomal protein of 25 kDa (SNAP-25) and syntaxin 1 reduces rapid exocytosis in insulin-secreting cells
Jenny Vikman et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2006)
The unique cytoarchitecture of human pancreatic islets has implications for islet cell function
O Cabrera et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Glucose-sensing mechanisms in pancreatic β-cells
PE MacDonald et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2005)
Mechanisms of β-cell death in type 2 diabetes
MY Donath et al.
DIABETES (2005)
Mechanisms of pancreatic β-cell death in type 1 and type 2 diabetes -: Many differences, few similarities
M Cnop et al.
DIABETES (2005)
Loss of ARNT/HIF1β mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes
JE Gunton et al.
CELL (2005)
Cholinergic stimulation of amylase secretion from pancreatic acinar cells studied with muscarinic acetylcholine receptor mutant mice
D Gautam et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy
M Brissova et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2005)
APE: Analyses of Phylogenetics and Evolution in R language
E Paradis et al.
BIOINFORMATICS (2004)
Superoxide-mediated activation of uncoupling protein 2 causes pancreatic beta cell dysfunction
S Krauss et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
AE Butler et al.
DIABETES (2003)
Glucose sensing in pancreatic beta-cells - A model for the study of other glucose-regulated cells in gut, pancreas, and hypothalamus
FC Schuit et al.
DIABETES (2001)
分享论文
