相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Alzheimer's Disease and Diabetes: Insulin Signaling as the Bridge Linking Two Pathologies
Jonathan Chang-Cheng Shieh et al.
MOLECULAR NEUROBIOLOGY (2020)
Metformin and cognition from the perspectives of sex, age, and disease
Kiran Chaudhari et al.
GEROSCIENCE (2020)
Metformin treatment prevents amyloid plaque deposition and memory impairment in APP/PS1 mice
Zhenri Ou et al.
BRAIN BEHAVIOR AND IMMUNITY (2018)
Ethyl acetate fraction from Hibiscus sabdariffa L. attenuates diabetes-associated cognitive impairment in mice
Tae Wan Seung et al.
FOOD RESEARCH INTERNATIONAL (2018)
Targeting Insulin for Alzheimer's Disease: Mechanisms, Status and Potential Directions
Jung Hyun Lee et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
beta-Amyloid Induces Pathology-Related Patterns of Tau Hyperphosphorylation at Synaptic Terminals
Hsin-Yi Wu et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2018)
Mitochondrial dysfunction contribute to diabetic neurotoxicity induced by streptozocin in mice: protective effect of Urtica dioica and pioglitazone
Mohammad Shokrzadeh et al.
TOXICOLOGY MECHANISMS AND METHODS (2018)
Mitochondrial dysfunction contribute to diabetic neurotoxicity induced by streptozocin in mice: protective effect of Urtica dioica and pioglitazone
Mohammad Shokrzadeh et al.
TOXICOLOGY MECHANISMS AND METHODS (2018)
The Implication of the Brain Insulin Receptor in Late Onset Alzheimer's Disease Dementia
Jaume Folch et al.
PHARMACEUTICALS (2018)
Recent novel approaches to limit oxidative stress and inflammation in diabetic complications
Raelene J. Pickering et al.
CLINICAL & TRANSLATIONAL IMMUNOLOGY (2018)
Metformin activation of AMPK suppresses AGE-induced inflammatory response in hNSCs
Ming-Min Chung et al.
EXPERIMENTAL CELL RESEARCH (2017)
Insulin deficiency results in reversible protein kinase A activation and tau phosphorylation
Judith M. van der Harg et al.
NEUROBIOLOGY OF DISEASE (2017)
The role of astrocytes in amyloid production and Alzheimer's disease
Georgia R. Frost et al.
OPEN BIOLOGY (2017)
Effects of the Insulin Sensitizer Metformin in Alzheimer Disease: Pilot Data From a Randomized Placebo-controlled Crossover Study
Aaron M. Koenig et al.
ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2017)
Mitochondrial dysfunction associated with nitric oxide pathways in glutamate neurotoxicity
Walter Manucha
CLINICA E INVESTIGACION EN ARTERIOSCLEROSIS (2017)
Prolonged metformin treatment leads to reduced transcription of Nrf2 and neurotrophic factors without cognitive impairment in older C57BL/6J mice
Joanne S. Allard et al.
BEHAVIOURAL BRAIN RESEARCH (2016)
Effects of metformin on inflammation and short-term memory in streptozotocin-induced diabetic mice
Wilma Helena Oliveira et al.
BRAIN RESEARCH (2016)
Activation of the cAMP-PKA pathway Antagonizes Metformin Suppression of Hepatic Glucose Production
Ling He et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Mitochondrial dysfunction precedes depression of AMPK/AKT signaling in insulin resistance induced by high glucose in primary cortical neurons
Yunhua Peng et al.
JOURNAL OF NEUROCHEMISTRY (2016)
The rise and fall of insulin signaling in Alzheimer's disease
B. Chami et al.
METABOLIC BRAIN DISEASE (2016)
Conceptual convergence: increased inflammation is associated with increased basal ganglia glutamate in patients with major depression
E. Haroon et al.
MOLECULAR PSYCHIATRY (2016)
Differential metformin dose-dependent effects on cognition in rats: role of Akt
Dalia K. Mostafa et al.
PSYCHOPHARMACOLOGY (2016)
Metformin, besides exhibiting strong in vivo anti-inflammatory properties, increases mptp-induced damage to the nigrostriatal dopaminergic system
Afrah A. K. Ismaiel et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2016)
Metformin Prevents Cisplatin-Induced Cognitive Impairment and Brain Damage in Mice
Wenjun Zhou et al.
PLOS ONE (2016)
Metformin increases APP expression and processing via oxidative stress, mitochondrial dysfunction and NF-κB activation: Use of insulin to attenuate metformin's effect
Pasquale Picone et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2015)
Aberrant insulin signaling in Alzheimer's disease: current knowledge
Gaurav Bedse et al.
FRONTIERS IN NEUROSCIENCE (2015)
Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease
Amy M. Pooler et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2015)
Type 2 Diabetes and Antidiabetic Medications in Relation to Dementia Diagnosis
Chin Cheng et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2014)
Resveratrol and Endothelial Nitric Oxide
Ning Xia et al.
MOLECULES (2014)
Diethylcarbamazine Reduces Chronic Inflammation and Fibrosis in Carbon Tetrachloride- (CCl4-) Induced Liver Injury in Mice
Sura Wanessa Santos Rocha et al.
MEDIATORS OF INFLAMMATION (2014)
Reversal of neurobehavioral and neurochemical alterations in STZ-induced diabetic rats by FeTMPyP, a peroxynitrite decomposition catalyst and 1,5-Isoquinolinediol a poly(ADP-ribose) polymerase inhibitor
Ashok Jangra et al.
NEUROLOGICAL RESEARCH (2014)
Astrocytic and microglial response in experimentally induced diabetic rat brain
Aarti Nagayach et al.
METABOLIC BRAIN DISEASE (2014)
The dual role of astrocyte activation and reactive gliosis
Milos Pekny et al.
NEUROSCIENCE LETTERS (2014)
Metformin has adenosine-monophosphate activated protein kinase (AMPK)-independent effects on LPS-stimulated rat primary microglial cultures
Krzysztof Łabuzek et al.
Pharmacological Reports (2014)
Insulin in the brain: its pathophysiological implications for states related with central insulin resistance, type 2 diabetes and alzheimer's disease
Enrique Blazquez et al.
FRONTIERS IN ENDOCRINOLOGY (2014)
Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer's disease
Hwan-Ching Tai et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2014)
NMDA and AMPA receptor mediated excitotoxicity in cerebral cortex of streptozotocin induced diabetic rat: Ameliorating effects of curcumin
S. Jayanarayanan et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2013)
Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP
Russell A. Miller et al.
NATURE (2013)
Neurodegeneration in Streptozotocin-Induced Diabetic Rats Is Attenuated by Treatment with Resveratrol
Yu-Hong Jing et al.
NEUROENDOCRINOLOGY (2013)
Role of the eNOS-NO System in Regulating the Antiproteinuric Effects of VEGF Receptor 2 Inhibition in Diabetes
Andrew Advani et al.
BIOMED RESEARCH INTERNATIONAL (2013)
Inhibitory phosphorylation of GSK-3β by AKT, PKA, and PI3K contributes to high NaCl-induced activation of the transcription factor NFAT5 (TonEBP/OREBP)
Xiaoming Zhou et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2013)
The Synaptic Accumulation of Hyperphosphorylated Tau Oligomers in Alzheimer Disease Is Associated With Dysfunction of the Ubiquitin-Proteasome System
Hwan-Ching Tai et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
Metformin Activates an Atypical PKC-CBP Pathway to Promote Neurogenesis and Enhance Spatial Memory Formation
Jing Wang et al.
CELL STEM CELL (2012)
Mechanisms Underlying Insulin Deficiency-Induced Acceleration of β-Amyloidosis in a Mouse Model of Alzheimer's Disease
Latha Devi et al.
PLOS ONE (2012)
Signaling Mechanism of Poly(ADP-Ribose) Polymerase-1 (PARP-1) in Inflammatory Diseases
Xueqing Ba et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation
Mireille Belanger et al.
CELL METABOLISM (2011)
Metformin attenuates ventricular hypertrophy by activating the AMP-activated protein kinase-endothelial nitric oxide synthase pathway in rats
Cheng-Xi Zhang et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2011)
IDF Diabetes Atlas: Global estimates of the prevalence of diabetes for 2011 and 2030
David R. Whiting et al.
DIABETES RESEARCH AND CLINICAL PRACTICE (2011)
PARP inhibitors: New tools to protect from inflammation
Vincenzo Giansanti et al.
BIOCHEMICAL PHARMACOLOGY (2010)
Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models
Lars M. Ittner et al.
CELL (2010)
Amyloid beta oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors
Elena Alberdi et al.
CELL CALCIUM (2010)
Type 1 diabetes exaggerates features of Alzheimer's disease in APP transgenic mice
Corinne G. Jolivalt et al.
EXPERIMENTAL NEUROLOGY (2010)
Aβ Oligomers Cause Localized Ca2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines
Hans Zempel et al.
JOURNAL OF NEUROSCIENCE (2010)
Insulin deficiency exacerbates cerebral amyloidosis and behavioral deficits in an Alzheimer transgenic mouse model
Xu Wang et al.
MOLECULAR NEURODEGENERATION (2010)
Ambivalent effects of compound C (dorsomorphin) on inflammatory response in LPS-stimulated rat primary microglial cultures
Krzysztof Labuzek et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2010)
Transsynaptic Progression of Amyloid-β-Induced Neuronal Dysfunction within the Entorhinal-Hippocampal Network
Julie A. Harris et al.
NEURON (2010)
Endothelial dysfunction and vascular disease
P. M. Vanhoutte et al.
ACTA PHYSIOLOGICA (2009)
Cognitive dysfunction and hippocampal changes in experimental type 1 diabetes
Edgardo O. Alvarez et al.
BEHAVIOURAL BRAIN RESEARCH (2009)
Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription
Yaomin Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Shared principles in NF-κB signaling
Matthew S. Hayden et al.
CELL (2008)
Defective Insulin Signaling Pathway and Increased Glycogen Synthase Kinase-3 Activity in the Brain of Diabetic Mice: Parallels With Alzheimer's Disease and Correction by Insulin
C. G. Jolivalt et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2008)
Mechanisms of Action of Metformin in Type 2 Diabetes and Associated Complications: An Overview
Sonia Correia et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2008)
Insulin dysfunction induces in vivo tau hyperphosphorylation through distinct mechanisms
Emmanuel Planel et al.
JOURNAL OF NEUROSCIENCE (2007)
Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity
Vittorio Calabrese et al.
NATURE REVIEWS NEUROSCIENCE (2007)
Metformin restores the penile expression of nitric oxide synthase in high-fat-fed obese rats
Yong-Woon Kim et al.
JOURNAL OF ANDROLOGY (2007)
AMP-activated protein kinase mediates VEGF-stimulated endothelial NO production
James A. Reihill et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Diabetes-induced cerebrovascular dysfunction: Role of poly(ADP-ribose) polymerase
Denise M. Arrick et al.
MICROVASCULAR RESEARCH (2007)
Deadly conversations: Nuclear-mitochondrial cross-talk
VL Dawson et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2004)
Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction?
JL Evans et al.
DIABETES (2003)
Tyrosine phosphorylation of ionotropic glutamate receptors by Fyn or Src differentially modulates their susceptibility to calpain and enhances their binding to spectrin and PSD-95
YQ Rong et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Characterization of Fyn-mediated tyrosine phosphorylation sites on GluRε2 (NR2B) subunit of the N-methyl-D-aspartate receptor
T Nakazawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)