期刊
POLYMERS
卷 13, 期 12, 页码 -出版社
MDPI
DOI: 10.3390/polym13121929
关键词
antifouling; surface plasmon resonance; clinical diagnosis; food safety; biosensing
资金
- MUR Prin 2017 [2017RHX2E4]
- European Union's Horizon 2020 research and innovation programme [764281]
- Universita degli Studi di Catania, STARTING GRANT 2020, project PATmiREC
Strategies for developing antifouling surface coatings are essential for surface plasmon resonance (SPR) sensing in various analytical fields, such as clinical diagnostics and food quality control. This review emphasizes the importance of using appropriate antifouling materials to achieve excellent biosensing performance and highlights progress in overcoming challenges related to target detection in complex samples.
Strategies to develop antifouling surface coatings are crucial for surface plasmon resonance (SPR) sensing in many analytical application fields, such as detecting human disease biomarkers for clinical diagnostics and monitoring foodborne pathogens and toxins involved in food quality control. In this review, firstly, we provide a brief discussion with considerations about the importance of adopting appropriate antifouling materials for achieving excellent performances in biosensing for food safety and clinical diagnosis. Secondly, a non-exhaustive landscape of polymeric layers is given in the context of surface modification and the mechanism of fouling resistance. Finally, we present an overview of some selected developments in SPR sensing, emphasizing applications of antifouling materials and progress to overcome the challenges related to the detection of targets in complex matrices relevant for diagnosis and food biosensing.
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