期刊
POLYMERS
卷 13, 期 11, 页码 -出版社
MDPI
DOI: 10.3390/polym13111847
关键词
wear particle; dodecyl gallate; highly cross-linked polyethylene; bone resorption; wear rate; wear test; total knee arthroplasty; implant fixation
资金
- National Natural Science Foundation of China [2016YFC1101904]
The study evaluated the use of HXLPE supplemented with DG as tibial inserts in TKA, showing promising wear resistance and characteristics of wear particles. HXLPE-DG demonstrated advantages over commonly used materials and potential application in TKA.
Background: the wear of tibial insert is still one of primary factors leading to failure of total knee arthroplasty (TKA). Dodecyl gallate (DG) has shown improvements in the oxidation stability of highly cross-linked polyethylene (HXLPE). This study aimed to assess the application of HXLPE supplemented with DG (HXLPE-DG) on the tibial insert in TKA concerning the wear resistance and the potential impact on implant fixation; Methods: tibial inserts made of HXLPE-DG were subjected to a 3 million loading-cycle wear test following ISO 14243-1:2009. The loss of mass and wear rate of the tibial inserts were calculated. The quantity, size,- and shape of wear particles were recorded; Results: the test specimens lost an average mass of 16.00 mg +/- 0.94 mg, and were on an average wear rate of 3.92 mg/million cycles +/- 0.19 mg/million cycles. The content of wear particles in the calf serum medium was 3.94 x 10(8) particles/mL +/- 3.93 x 10(7) particles/mL, 96.66% +/- 0.77% of the particles had an equivalent circular diameter less than 0.5 mu m. The aspect ratio of wear particles was 1.40 (min: 1.01; max: 6.42). Conclusions: HXLPE-DG displayed advantages over the commonly used materials for tibial inserts and presented the potential of application in TKA.
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