4.7 Article

Elucidating the mechanism by which synthetic helper peptides sensitize Pseudomonas aeruginosa to multiple antibiotics

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Summary: Li, Cebrian et al. demonstrate that a combination of peptide D-11 and vancomycin shows potent antimicrobial activity against a panel of Gram-negative pathogens without apparent toxicity. They also find that this combination effectively clears Pseudomonas aeruginosa in mice, providing a potential antimicrobial therapy for humans.

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