相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。A Drosophila platform identifies a novel, personalized therapy for a patient with adenoid cystic carcinoma
Erdem Bangi et al.
ISCIENCE (2021)
Rethinking drug design in the artificial intelligence era
Petra Schneider et al.
NATURE REVIEWS DRUG DISCOVERY (2020)
ReSimNet: drug response similarity prediction using Siamese neural networks
Minji Jeon et al.
BIOINFORMATICS (2019)
Extended Multitarget Pharmacology of Anticancer Drugs
Da Shi et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2019)
Integrated computational and Drosophila cancer model platform captures previously unappreciated chemicals perturbing a kinase network
Peter M. U. Ung et al.
PLOS COMPUTATIONAL BIOLOGY (2019)
A personalized platform identifies trametinib plus zoledronate for a patient with KRAS-mutant metastatic colorectal cancer
Erdem Bangi et al.
SCIENCE ADVANCES (2019)
Deep learning enables rapid identification of potent DDR1 kinase inhibitors
Alex Zhavoronkov et al.
NATURE BIOTECHNOLOGY (2019)
Signatures of cell death and proliferation in perturbation transcriptomics data-from confounding factor to effective prediction
Bence Szalai et al.
NUCLEIC ACIDS RESEARCH (2019)
Comparison Study of Computational Prediction Tools for Drug-Target Binding Affinities
Maha Thafar et al.
FRONTIERS IN CHEMISTRY (2019)
KinaMetrix: a web resource to investigate kinase conformations and inhibitor space
Rayees Rahman et al.
NUCLEIC ACIDS RESEARCH (2019)
What Makes a Kinase Promiscuous for Inhibitors?
Sonya M. Hanson et al.
CELL CHEMICAL BIOLOGY (2019)
Estimation of the Percentage of US Patients With Cancer Who Benefit From Genome-Driven Oncology
John Marquart et al.
JAMA ONCOLOGY (2018)
Predicting protein targets for drug-like compounds using transcriptomics
Nicolas A. Pabon et al.
PLOS COMPUTATIONAL BIOLOGY (2018)
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
Antoine Daina et al.
SCIENTIFIC REPORTS (2017)
Multi-targeting Drug Community Challenge
Avner Schlessinger et al.
CELL CHEMICAL BIOLOGY (2017)
A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles
Aravind Subramanian et al.
CELL (2017)
A Landscape of Pharmacogenomic Interactions in Cancer
Francesco Iorio et al.
CELL (2016)
A new paradigm for navigating compound property related drug attrition
Patrick Barton et al.
DRUG DISCOVERY TODAY (2016)
ZINC 15-Ligand Discovery for Everyone
Teague Sterling et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2015)
Resistance to BRAF-targeted therapy in melanoma
Ryan J. Sullivan et al.
EUROPEAN JOURNAL OF CANCER (2013)
Expression of Alzheimer-Like Pathological Human Tau Induces a Behavioral Motor and Olfactory Learning Deficit in Drosophila melanogaster
Cindy Beharry et al.
JOURNAL OF ALZHEIMERS DISEASE (2013)
Chemical genetic discovery of targets and anti-targets for cancer polypharmacology
Arvin C. Dar et al.
NATURE (2012)
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
Jordi Barretina et al.
NATURE (2012)
The tyrosine kinase inhibitor ZD6474 blocks proliferation of RET mutant medullary thyroid carcinoma cells
Donata Vitagliano et al.
ENDOCRINE-RELATED CANCER (2011)
Comprehensive analysis of kinase inhibitor selectivity
Mindy I. Davis et al.
NATURE BIOTECHNOLOGY (2011)
Dysregulation of bone remodeling by imatinib mesylate
Kate Vandyke et al.
BLOOD (2010)
High-Content, Image-Based Screening for Drug Targets in Yeast
Shinsuke Ohnuki et al.
PLOS ONE (2010)
Cytoskeleton proteins are modulators of mutant tau-induced neurodegeneration in Drosophila
Olivier Blard et al.
HUMAN MOLECULAR GENETICS (2007)
A drosophila model of multiple endocrine neoplasia type 2
RD Read et al.
GENETICS (2005)
ZD6474 suppresses oncogenic RET isoforms in a Drosophila model for type 2 multiple endocrine neoplasia syndromes and papillary thyroid carcinoma
M Vidal et al.
CANCER RESEARCH (2005)