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Alexander S. Krois et al.
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Eileen E. M. Furlong et al.
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Joseph G. Azofeifa et al.
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Zdenek Andrysik et al.
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Darren J. Baker et al.
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BEDTools: a flexible suite of utilities for comparing genomic features
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The Sequence Alignment/Map format and SAMtools
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M. D. Wyatt et al.
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Multiple conformations of full-length p53 detected with single-molecule fluorescence resonance energy transfer
Fang Huang et al.
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A Subramanian et al.
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JC Bourdon et al.
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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
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