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A consensus integrated care pathway for patients with primary biliary cholangitis: a guideline-based approach to clinical care of patients

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出版社

TAYLOR & FRANCIS LTD
DOI: 10.1080/17474124.2021.1945919

关键词

American association for the study of liver diseases (aasld); european association for the study of the liver (easl); obeticholic acid (oca); patient care pathway; primary biliary cholangitis (pbc); ursodeoxycholic acid (udca)

资金

  1. Intercept Pharma Europe Ltd.

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The development of a 'PBC Integrated Patient Care Pathway' by expert consensus simplifies and standardizes the management of PBC for clinicians based on current practice. This tool complements the EASL Clinical Practice Guidelines for the diagnosis and management of PBC patients, providing a practical decision tree and supporting the adoption of varied care provision models for patients with PBC.
Introduction Primary biliary cholangitis (PBC) is an infrequent, immune-mediated cholestatic liver disease, which can lead to liver fibrosis, cirrhosis and complications of end-stage liver disease. The established goals of treatment of PBC are prevention of end-stage liver disease and amelioration of associated symptoms. The European Association for the Study of the Liver (EASL) management guidelines provide extensive recommendations on the diagnosis and management of PBC. Areas covered This article describes the development by expert consensus of a 'PBC Integrated Patient Care Pathway' to simplify and standardize the management of PBC for clinicians based on current practice. Expert opinion Guideline adoption is potentially poor in practice since most patients with PBC in the community are seen by general gastroenterologists or hepatologists without a special interest in autoimmune liver disease. The PBC Integrated Patient Care Pathway is a best practice tool for clinicians designed to complement the EASL Clinical Practice Guidelines for the diagnosis and management of PBC patients. It gives clinicians a practical decision tree of the key steps in PBC management, thereby providing a simplified framework and an opportunity for more uniform practice that supports the safe and timely adoption of varied models of care provision to patients with PBC.

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